Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sara Abouelasrar Salama"'
Autor:
Marfa Blanter, Maaike Cockx, Liesel Wittebols, Sara Abouelasrar Salama, Mirre De Bondt, Nele Berghmans, Noëmie Pörtner, Lotte Vanbrabant, Natalie Lorent, Mieke Gouwy, Mieke Boon, Sofie Struyf
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for PCD and to date there are no specific treatments available. Neutrophils are a crucial part o
Externí odkaz:
https://doaj.org/article/f1f7b798d1e747da96aade424115f043
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Originally, it was thought that a single serum amyloid A (SAA) protein was involved in amyloid A amyloidosis, but in fact, SAA represents a four‐membered family wherein SAA1 and SAA2 are acute phase proteins (A-SAA). SAA is highly conserved through
Externí odkaz:
https://doaj.org/article/f89a0274955148a2a1992a8dbe679d81
Autor:
Marfa Blanter, Seppe Cambier, Mirre De Bondt, Lotte Vanbrabant, Noëmie Pörtner, Sara Abouelasrar Salama, Mieke Metzemaekers, Pedro Elias Marques, Sofie Struyf, Paul Proost, Mieke Gouwy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils are the most abundant leukocytes in human blood and the first cells responding to infection and injury. Due to their limited ex vivo lifespan and the impossibility to cryopreserve or expand them in vitro, neutrophils need to be purified f
Externí odkaz:
https://doaj.org/article/22b2a53576ab4daf8896b0c851e25066
Autor:
Mieke Metzemaekers, Sara Abouelasrar Salama, Jennifer Vandooren, Anneleen Mortier, Rik Janssens, Sofie Vandendriessche, Eva Ganseman, Erik Martens, Mieke Gouwy, Barbara Neerinckx, Patrick Verschueren, Lien De Somer, Carine Wouters, Sofie Struyf, Ghislain Opdenakker, Jo Van Damme, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
With ELISAs one detects the ensemble of immunoreactive molecules in biological samples. For biomolecules undergoing proteolysis for activation, potentiation or inhibition, other techniques are necessary to study biology. Here we develop methodology t
Externí odkaz:
https://doaj.org/article/98eedf5312eb4a159a82972e990bd062
Autor:
Sara Abouelasrar Salama, Mirre De Bondt, Mieke De Buck, Nele Berghmans, Paul Proost, Vivian Louise Soares Oliveira, Flavio A. Amaral, Mieke Gouwy, Jo Van Damme, Sofie Struyf
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Infection, sterile injury, and chronic inflammation trigger the acute phase response in order to re-establish homeostasis. This response includes production of positive acute phase proteins in the liver, such as members of the serum amyloid A (SAA) f
Externí odkaz:
https://doaj.org/article/8f543bb649f0453ea4a489ed95253619
Autor:
Sara Abouelasrar Salama, Mirre De Bondt, Nele Berghmans, Mieke Gouwy, Vivian Louise Soares de Oliveira, Sergio C. Oliveira, Flavio A. Amaral, Paul Proost, Jo Van Damme, Sofie Struyf, Mieke De Buck
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the years, a considerable amount of literature has been published attributing a wide range of b
Externí odkaz:
https://doaj.org/article/9d98eb1390c849428a2061beef83c39f
Autor:
Mieke Gouwy, Mieke De Buck, Sara Abouelasrar Salama, Jennifer Vandooren, Sofie Knoops, Noëmie Pörtner, Lotte Vanbrabant, Nele Berghmans, Ghislain Opdenakker, Paul Proost, Jo Van Damme, Sofie Struyf
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Serum amyloid A1 (SAA1) is a prototypic acute phase protein, induced to extremely high levels by physical insults, including inflammation and infection. Human SAA and its NH2-terminal part have been studied extensively in the context of amyloidosis.
Externí odkaz:
https://doaj.org/article/3129ec7921ea4eacb9e54df00eeefb16
Publikováno v:
Immunology
Serum amyloid A (SAA) is an acute-phase protein (APP) to which multiple immunological functions have been attributed. Regardless, the true biological role of SAA remains poorly understood. SAA is remarkably conserved in mammalian evolution, thereby s
Autor:
Noëmie Pörtner, Jo Van Damme, Sofie Struyf, Nele Berghmans, Alexandra De Zutter, Mieke Gouwy, Sara Abouelasrar Salama, Lotte Vanbrabant, Mieke De Buck
Publikováno v:
Journal of Interferon & Cytokine Research. 40:195-206
Chronic hepatitis C virus (HCV) infection accounts for a large proportion of hepatic fibrosis and carcinoma cases observed worldwide. Mechanisms involved in HCV-induced hepatic injury have yet to be fully elucidated. Of particular interest is the cap
Autor:
Sofie Struyf, Noëmie Pörtner, Maaike Cockx, Sofie Knoops, Pieter Ruytinx, Lotte Vanbrabant, Mieke Gouwy, Marfa Blanter, Natalie Lorent, Mieke Boon, Sara Abouelasrar Salama
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6172, p 6172 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6172, p 6172 (2021)
The airways of patients with primary ciliary dyskinesia (PCD) contain persistently elevated neutrophil numbers and CXCL8 levels. Despite their abundance, neutrophils fail to clear the airways from bacterial infections. We investigated whether neutrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c70725f535d260b3b9b9b08e608ba9b
https://lirias.kuleuven.be/handle/123456789/678077
https://lirias.kuleuven.be/handle/123456789/678077