Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sara A. Rubin"'
Autor:
Sara A. Rubin, Chloé S. Baron, Cecilia Pessoa Rodrigues, Madeleine Duran, Alexandra F. Corbin, Song P. Yang, Cole Trapnell, Leonard I. Zon
Publikováno v:
Journal of Experimental Medicine. 219
The zebrafish has proven to be a valuable model organism for studying hematopoiesis, but relatively little is known about zebrafish immune cell development and functional diversity. Elucidating key aspects of zebrafish lymphocyte development and expl
Autor:
Ondrej Stepanek, Veronika Horkova, Arthur Weiss, Ian R Fallahee, Wan-Lin Lo, Leonard I. Zon, Weiguo Zhang, Neel H. Shah, John Kuriyan, Sara A. Rubin
Publikováno v:
Nature immunology, vol 20, iss 11
Nature immunology
Nature immunology
Self/non-self discrimination is central to T cell-mediated immunity. The kinetic proofreading model can explain T cell antigen receptor (TCR) ligand discrimination; however, the rate-limiting steps have not been identified. Here, we show that tyrosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec73b1c944a01e34a12cdcf3c78025fa
https://escholarship.org/uc/item/7863s7bx
https://escholarship.org/uc/item/7863s7bx
Publikováno v:
Blood. 138:4294-4294
The advent of single-cell RNA sequencing (scRNA-seq) has greatly expanded our appreciation for cell state diversity beyond classical developmental hierarchies and simple population subsets. In particular, rich transcriptional heterogeneity has been o
Autor:
Tyler B. Jacobson, Sophia Hsin-Jung Li, Joshua D. Rabinowitz, Zheyun Zhang, Sara A. Rubin, Meytal B. Higgins, Monica H. Wei, Junyoung O. Park, David M. Stevenson, Daniel Amador-Noguez, Lukas B. Tanner, Daven B. Khana
Publikováno v:
Nat Chem Biol
Glycolysis plays a central role in producing ATP and biomass. Its control principles, however, remain incompletely understood. Here, we develop a method that combines (2)H and (13)C tracers to determine glycolytic thermodynamics. Using this method, w
Publikováno v:
Blood. 136:32-32
Developmental hematopoietic stem and progenitor cells (HSPCs) have been thought to be largely replaced by adult hematopoietic stem cells (HSCs) after birth. Here, we performed simultaneous genetic lineage tracing by cellular barcoding and transcripti
Autor:
Jack Herrmann, Lisa M. Koonin, Sara E. Rubin, Anita Patel, Andrew R. Roszak, Rachel M Schulman
Publikováno v:
Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science. 12:76-84
Response to public health emergencies requires coordination across multiple sectors and effective use of existing resources in communities. With the expanded role of community pharmacists in public health during the past decade, their participation i
Publikováno v:
Journal of Public Health Management and Practice. 20:259-263
Publikováno v:
Journal of Public Health Management and Practice. 21:413-415
Autor:
Jing Fan, Sara A. Rubin, Yi-Fan Xu, Junyoung O. Park, Joshua D. Rabinowitz, Daniel Amador-Noguez, Tomer Shlomi
Publikováno v:
Nature chemical biology, vol 12, iss 7
Nature chemical biology
Nature chemical biology
In metabolism, available free energy is limited and must be divided across pathway steps to maintain a negative ΔG throughout. For each reaction, ΔG is log proportional both to a concentration ratio (reaction quotient to equilibrium constant) and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342f38afcf84b4a4911ccf625e512669
https://escholarship.org/uc/item/2gn8c7x5
https://escholarship.org/uc/item/2gn8c7x5
Autor:
Sara E. Rubin, Andrew R. Roszak
Publikováno v:
Journal of Public Health Management and Practice. 19:388-390