Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sara A. Healy"'
Autor:
Thomas L. Richie, L.W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei-Chun Chen, Yonas Abebe, Natasha KC, Sumana Chakravarty, David Dolberg, Sara A. Healy, Halimatou Diawara, Mahamadou S. Sissoko, Issaka Sagara, David M. Cook, Judith E. Epstein, Benjamin Mordmüller, Melissa Kapulu, Andrea Kreidenweiss, Blandine Franke-Fayard, Selidji T. Agnandji, María-Silvia A. López Mikue, Matthew B.B. McCall, Laura Steinhardt, Martina Oneko, Ally Olotu, Ashley M. Vaughan, James G. Kublin, Sean C. Murphy, Said Jongo, Marcel Tanner, Sodiomon B. Sirima, Matthew B. Laurens, Claudia Daubenberger, Joana C. Silva, Kirsten E. Lyke, Chris J. Janse, Meta Roestenberg, Robert W. Sauerwein, Salim Abdulla, Alassane Dicko, Stefan H. I. Kappe, B. Kim Lee Sim, Patrick E. Duffy, Peter G. Kremsner, Stephen L. Hoffman
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especi
Externí odkaz:
https://doaj.org/article/64ccc130995e4fbda0570808ef7ca47d
Autor:
Niharika Shukla, Wai Kwan Tang, Camila H. Coelho, Carole A. Long, Sara A. Healy, Issaka Sagara, Kazutoyo Miura, Patrick E. Duffy, Niraj H. Tolia
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Pfs25 is a leading antigen for a malaria transmission-blocking vaccine and shows moderate transmission-blocking activity and induction of rapidly decreasing antibody titers in clinical trials. A comprehensive definition of all transmission-r
Externí odkaz:
https://doaj.org/article/2b2a9cc4c3a14a22b8a2355e8bb81d9f
Autor:
Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vacc
Externí odkaz:
https://doaj.org/article/8adef3faef374367ad0d7275f5f65245
Autor:
Derrick Hau, Kathryn J. Pflughoeft, Marcellene A. Gates-Hollingsworth, Simranjit Kaur, Haydon J. Hill, Jose Arias-Umana, Chelsea C. Chung, Valerie L. Smith, Mark S. Riddle, Sara A. Healy, David P. AuCoin
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/21d64eeff2c54eb3a0cf9f0146a90caa
Autor:
Emily N. Reichert, Jen C. C. Hume, Issaka Sagara, Sara A. Healy, Mahamadoun H. Assadou, Merepen A. Guindo, Rebecca Barney, Andy Rashid, Ihn Kyung Yang, Allison Golden, Gonzalo J. Domingo, Patrick E. Duffy, Hannah C. Slater
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The recent expansion of tools designed to accurately quantify malaria parasite-produced antigens has enabled us to evaluate the performance of rapid diagnostic tests (RDTs) as a function of the antigens they detect—typically his
Externí odkaz:
https://doaj.org/article/7a3eed462c0d4a12ada01d94910993fb
Autor:
Camila H. Coelho, Wai Kwan Tang, Martin Burkhardt, Jacob D. Galson, Olga Muratova, Nichole D. Salinas, Thiago Luiz Alves e Silva, Karine Reiter, Nicholas J. MacDonald, Vu Nguyen, Raul Herrera, Richard Shimp, David L. Narum, Miranda Byrne-Steele, Wenjing Pan, Xiaohong Hou, Brittany Brown, Mary Eisenhower, Jian Han, Bethany J. Jenkins, Justin Y. A. Doritchamou, Margery G. Smelkinson, Joel Vega-Rodríguez, Johannes Trück, Justin J. Taylor, Issaka Sagara, Sara A. Healy, Jonathan P. Renn, Niraj H. Tolia, Patrick E. Duffy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/6d340eb64ddc42069695455873c33002
Autor:
Hama Diallo, Abdoulaye Katile, Jennifer L. Kwan, Mahamadou S. Sissoko, Sara A. Healy, Ogobara K. Doumbo, Patrick E. Duffy, Irfan Zaidi
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-10 (2019)
Abstract Background Immunity that limits malarial disease is acquired over time, but adults living in endemic areas continue to become infected and can require treatment for clinical illness. Gamma delta (γδ) T cells, particularly the Vδ2+ subset,
Externí odkaz:
https://doaj.org/article/28103ce5b4f6436899791be9d9303956
Autor:
Jacquelyn Lane, Thomas L. Richie, Bourama Kamate, Tooba Murshedkar, Patrick E. Duffy, Fanta Koita, Natasha Kc, Abdoulaye Katile, Ismaila Thera, Agnes Mwakingwe-Omari, Peter F. Billingsley, Stephen L. Hoffman, Anita Manoj, Cheick Oumar Guindo, Amagana Dolo, Merepen A Guindo, Eric R. James, Yacouba Samake, Kelly M. Rausch, Rathy Mohan, Karamoko Niare, B. Kim Lee Sim, Yonas Abebe, Kourane Sissoko, Alemush Imeru, Sara A. Healy, Zonghui Hu, Amadou Niangaly, Ogobara K. Doumbo, Aissatou Bah, Amatigue Zeguime, Mahamadou S Sissoko, Irfan Zaidi
Publikováno v:
Lancet Infect Dis
Summary Background WHO recently approved a partially effective vaccine that reduces clinical malaria in children, but increased vaccine activity is required to pursue malaria elimination. A phase 1 clinical trial was done in Mali, west Africa, to ass
Publikováno v:
Healy, S R, Morgan, E R, Prada, J M & Betson, M 2023, ' From fox to fork? Toxocara contamination of spinach grown in the south of England, UK ', Parasites and Vectors, vol. 16, 49 . https://doi.org/10.1186/s13071-023-05674-8
Background Toxocara canis and Toxocara cati are intestinal parasites of dogs, cats and foxes, with infected animals shedding eggs of the parasite in their faeces. If humans accidentally ingest embryonated Toxocara spp. eggs from the environment, seve
Autor:
Kassoum, Kayentao, Aissata, Ongoiba, Anne C, Preston, Sara A, Healy, Safiatou, Doumbo, Didier, Doumtabe, Abdrahamane, Traore, Hamadi, Traore, Adama, Djiguiba, Shanping, Li, Mary E, Peterson, Shinyi, Telscher, Azza H, Idris, Neville K, Kisalu, Kevin, Carlton, Leonid, Serebryannyy, Sandeep, Narpala, Adrian B, McDermott, Martin, Gaudinski, Siriman, Traore, Hamidou, Cisse, Mamadou, Keita, Jeff, Skinner, Zonghui, Hu, Amatigué, Zéguimé, Adama, Ouattara, M'Bouye, Doucoure, Amagana, Dolo, Abdoulaye, Djimdé, Boubacar, Traore, Robert A, Seder, Peter D, Crompton
Publikováno v:
The New England journal of medicine. 387(20)
CIS43LS is a monoclonal antibody that was shown to protect against controlledWe conducted a phase 2 trial to assess the safety and efficacy of a single intravenous infusion of CIS43LS againstIn Part B, 330 adults underwent randomization; 110 were ass