Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara A. Guasch"'
Autor:
Scott M. Krummey, Anna B. Morris, Jesica R. Jacobs, Donald J. McGuire, Satomi Ando, Katherine P. Tong, Weiwen Zhang, Jennifer Robertson, Sara A. Guasch, Koichi Araki, Christian P. Larsen, Brian D. Evavold, Haydn T. Kissick, Mandy L. Ford
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1282-1291.e5 (2020)
Summary: The identity of CD45 isoforms on the T cell surface changes following the activation of naive T cells and impacts intracellular signaling. In this study, we find that the anti-viral memory CD8+ T pool is unexpectedly comprised of both CD45RB
Externí odkaz:
https://doaj.org/article/d69652ad5ff041889716115077fdfc7b
Autor:
Christian P. Larsen, Sara A. Guasch, Maylene E. Wagener, Scott M. Krummey, Ching wen Chen, Danya Liu, Mandy L. Ford
Publikováno v:
The Journal of Immunology. 197:2009-2015
The affinity of a TCR binding to peptide:MHC profoundly impacts the phenotype and function of effector and memory cell differentiation. Little is known about the effect of low-affinity priming on memory cell generation and function, which is particul