Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Sara A. Gibson"'
Autor:
Etty N. Benveniste, Zhaoqi Yan, Hongwei Qin, Sara A. Gibson, Wei Yang, Hairong Wei, Jiahui Tao, Bingdong Sha
Publikováno v:
Mucosal immunology
Crohn's disease (CD), one of the major forms of inflammatory bowel disease (IBD), is characterized by chronic inflammation of the gastrointestinal tract and associated with aberrant CD4+ T-helper type 1 (Th1) and Th17 responses. Protein kinase 2 (CK2
Autor:
Matthew D. Gallovic, Sara A. Gibson, Brandon M. Johnson, Kristy M. Ainslie, Jonathan W. Williams, Wei-Chun Chou, Cole J. Batty, Jenny P.-Y. Ting, Glenn K. Matsushima, Eric M. Bachelder, Meng Deng, Jason W. Tam, Toru Uchimura, Silva Markovic-Plese, Madhan Thamilarasan
Publikováno v:
J Immunol
The cGAS–cyclic GMP–AMP (cGAMP)–stimulator of IFN genes (STING) pathway induces a powerful type I IFN (IFN-I) response and is a prime candidate for augmenting immunity in cancer immunotherapy and vaccines. IFN-I also has immune-regulatory funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c282d3bd55213316e3585e70877c11c5
https://europepmc.org/articles/PMC8406342/
https://europepmc.org/articles/PMC8406342/
Autor:
W. June Brickey, Leslie Freeman, Wei-Chun Chou, Liang Chen, Ge Zhang, Xianming Tan, Maureen A. Su, Kaixin Liang, Xian Chen, Sara A. Gibson, Ling Xie, Hao Guo, Yan Wang, Jenny P.-Y. Ting, Zengli Guo, Meng Deng, Yisong Y. Wan, Song Zhang, Stephanie A. Montgomery, Elena Rampanelli
Publikováno v:
Nature, vol 591, iss 7849
Nature, 591(7849), 300-305. Nature Publishing Group
Nature
Nature, 591(7849), 300-305. Nature Publishing Group
Nature
The inflammasome initiates innate defense and inflammatory response by activating caspase-1 and pyroptotic cell death in myeloid cells1,2. It is comprised of an innate immune receptor/sensor, pro-caspase-1, and a common adaptor molecule, ASC (apoptot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd34f70638e24ac3e9bfc31ae2d5f38
Publikováno v:
The Journal of Experimental Medicine
An extensive crosstalk between host and intestinal microbiota contributes to the development and maturation of intestinal epithelium and immune system. This review details the interplay between nucleotide-binding domain leucine-rich repeat containing
Publikováno v:
The Journal of Immunology. 201:383-392
Growing evidence demonstrates that the highly conserved serine/threonine kinase CK2 promotes Th17 cell differentiation while suppressing the generation of Foxp3+ regulatory T cells (Tregs); however, the exact mechanism by which CK2 regulates the Th17
Publikováno v:
Clinical Immunology. 189:4-13
The Janus Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) signaling pathway is utilized by numerous cytokines and interferons, and is essential for the development and function of both innate and adaptive immunity. Aberrant activ
Autor:
Stephanie A. Montgomery, Leslie Freeman, W. June Brickey, Ge Zhang, Hao Guo, Yan Wang, Meng Deng, Song Zhang, Elena Rampanelli, Sara A. Gibson, Wei-Chun Chou, Liang Chen, Ling Xie, Yisong Y. Wan, Xian Chen, Xianming Tan, Maureen A. Su, Jenny P.-Y. Ting, Kaixin Liang, Zengli Guo
Publikováno v:
Nature. 592:E29-E29
Autor:
Xin Xu, Amit Gaggar, Shi Wei, Hongwei Qin, Jiping Zhao, Sara A. Gibson, Chenglong Li, Hao Yu, Etty N. Benveniste, Yudong Liu, Pui-Kai Li, Zhaoqi Yan
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 311:L868-L880
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are diseases with high mortality. Macrophages and neutrophils are responsible for inflammatory responses in ALI and ARDS, which are characterized by excessive production of proinf
Autor:
Hairong Wei, Wei Yang, Luke Parkitny, Forrest Collins, Amy S. Weinmann, Kevin S. Lee, Sara A. Gibson, Etty N. Benveniste, Jessy S. Deshane, Zhaoqi Yan, Hongwei Qin, Wayne Cheng
Publikováno v:
JCI Insight. 4
Dysregulation of the JAK/STAT signaling pathway is associated with Multiple Sclerosis (MS) and its mouse model, Experimental Autoimmune Encephalomyelitis (EAE). Suppressors Of Cytokine Signaling (SOCS) negatively regulate the JAK/STAT pathway. We pre
Autor:
Zhaoqi, Yan, Wei, Yang, Luke, Parkitny, Sara A, Gibson, Kevin S, Lee, Forrest, Collins, Jessy S, Deshane, Wayne, Cheng, Amy S, Weinmann, Hairong, Wei, Hongwei, Qin, Etty N, Benveniste
Publikováno v:
JCI insight. 5
Dysregulation of the JAK/STAT signaling pathway is associated with multiple sclerosis (MS) and its mouse model, experimental autoimmune encephalomyelitis (EAE). Suppressors of cytokine signaling (SOCS) negatively regulate the JAK/STAT pathway. We pre