Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sara A. Abdulla"'
Autor:
Nuha T. Swaidan, Nada H. Soliman, Ahmed T. Aboughalia, Toqa Darwish, Ruba O. Almeshal, Azhar A. Al-Khulaifi, Rowaida Z. Taha, Rania Alanany, Ahmed Y. Hussein, Salam Salloum-Asfar, Sara A. Abdulla, Abdallah M. Abdallah, Mohamed M. Emara
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM factors are a robust reprogr
Externí odkaz:
https://doaj.org/article/3afa19d27b0f491590abfc71c2b647a5
Autor:
Areej Mesleh, Hanan Ehtewish, Katie Lennard, Houari B. Abdesselem, Fouad Al-Shaban, Julie Decock, Nehad M. Alajez, Abdelilah Arredouani, Mohamed M. Emara, Omar Albagha, Lawrence W. Stanton, Sara A. Abdulla, Jonathan M. Blackburnand, Omar M. A. El-Agnaf
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionAutism spectrum disorder (ASD) is a neurodevelopmental condition characterized by defects in two core domains, social/communication skills and restricted/repetitive behaviors or interests. There is no approved biomarker for ASD diagnosis,
Externí odkaz:
https://doaj.org/article/65e4406e67b549829aa37557b1ed0528
Autor:
Parisa Moridian, Navid Ghassemi, Mahboobeh Jafari, Salam Salloum-Asfar, Delaram Sadeghi, Marjane Khodatars, Afshin Shoeibi, Abbas Khosravi, Sai Ho Ling, Abdulhamit Subasi, Roohallah Alizadehsani, Juan M. Gorriz, Sara A. Abdulla, U. Rajendra Acharya
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Autism spectrum disorder (ASD) is a brain condition characterized by diverse signs and symptoms that appear in early childhood. ASD is also associated with communication deficits and repetitive behavior in affected individuals. Various ASD detection
Externí odkaz:
https://doaj.org/article/dbd6ea6f07ef4193a238307abd39999d
Autor:
Areej Mesleh, Hanan Ehtewish, Alberto de la Fuente, Hawra Al-shamari, Iman Ghazal, Fatema Al-Faraj, Fouad Al-Shaban, Houari B. Abdesselem, Mohamed Emara, Nehad M. Alajez, Abdelilah Arredouani, Julie Decock, Omar Albagha, Lawrence W. Stanton, Sara A. Abdulla, Omar M. A. El-Agnaf
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7443 (2023)
Autism spectrum disorder (ASD) is an umbrella term that encompasses several disabling neurodevelopmental conditions. These conditions are characterized by impaired manifestation in social and communication skills with repetitive and restrictive behav
Externí odkaz:
https://doaj.org/article/55e4b8813e26462890ee5e681a32c555
Autor:
Nuha T. Swaidan, Salam Salloum-Asfar, Freshteh Palangi, Khaoula Errafii, Nada H. Soliman, Ahmed T. Aboughalia, Abdul Haseeb S. Wali, Sara A. Abdulla, Mohamed M. Emara
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Abstract Although many factors have been identified and used to enhance the iPSC reprogramming process, its efficiency remains quite low. In addition, reprogramming efficacy has been evidenced to be affected by disease mutations that are present in p
Externí odkaz:
https://doaj.org/article/7ae603a437084f20abc470cc1eac7cb6
Autor:
Houda Yasmine Ali Moussa, Nimshitha Manaph, Gowher Ali, Selma Maacha, Kyung Chul Shin, Samia M. Ltaief, Vijay Gupta, Yongfeng Tong, Janarthanan Ponraj, Salam Salloum-Asfar, Said Mansour, Fouad A. Al-Shaban, Hyung-Goo Kim, Lawrence W. Stanton, Jean-Charles Grivel, Sara A. Abdulla, Abeer R. Al-Shammari, Yongsoo Park
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Extracellular vesicles (EVs) are membrane vesicles released from cells to the extracellular space, involved in cell-to-cell communication by the horizontal transfer of biomolecules such as proteins and RNA. Because EVs can cross the blood-brain barri
Externí odkaz:
https://doaj.org/article/f7807d86e65542a59f1dad50f74540a1
Autor:
Mustafa T. Ardah, Simona S. Ghanem, Sara A. Abdulla, Guohua Lv, Mohamed M. Emara, Katerina E. Paleologou, Nishant N. Vaikath, Jia-Hong Lu, Min Li, Konstantinos Vekrellis, David Eliezer, Omar M. A. El-Agnaf
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-21 (2020)
Abstract Background Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with
Externí odkaz:
https://doaj.org/article/20d1bd5274794f01b0343a5862a81e46
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102500- (2021)
Autism spectrum disorder (ASD) is a childhood-onset neurodevelopmental disorder characterized by social interaction, behavior, and communication challenges. Here, we generated an induced pluripotent stem cell (iPSC) line, QBRIi013-A using a non-integ
Externí odkaz:
https://doaj.org/article/77c154abc38a443aab3d0ad47216e0d4
Publikováno v:
Cells, Vol 11, Iss 23, p 3833 (2022)
Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. However, this process
Externí odkaz:
https://doaj.org/article/39c4c427f4f94eb58e7f671008663588
Autor:
Salam Salloum-Asfar, Rudolf Engelke, Hanaa Mousa, Neha Goswami, I. Richard Thompson, Freshteh Palangi, Kamal Kamal, Muna N. Al-Noubi, Frank Schmidt, Sara A. Abdulla, Mohamed M. Emara
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates that different types of ce
Externí odkaz:
https://doaj.org/article/1205d84d15c8408f8cc7c6e129328464