Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sara, Violante"'
Autor:
Ana Romarowski, Jasna Fejzo, Saman Nayyab, David Martin-Hidalgo, Maria G. Gervasi, Melanie Balbach, Sara Violante, Ana M. Salicioni, Justin Cross, Lonny R. Levin, Jochen Buck, Pablo E. Visconti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Mammalian sperm must undergo capacitation to become fertilization-competent. While working on mice, we recently developed a new methodology for treating sperm in vitro, which results in higher rates of fertilization and embryo development after in vi
Externí odkaz:
https://doaj.org/article/6ffc929c917e44778766d6d8e9c7d9a5
Autor:
Melanie Balbach, Lubna Ghanem, Sara Violante, Aye Kyaw, Ana Romarowski, Justin R. Cross, Pablo E. Visconti, Lonny R. Levin, Jochen Buck
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Mammalian sperm require sufficient energy to support motility and capacitation for successful fertilization. Previous studies cataloging the changes to metabolism in sperm explored ejaculated human sperm or dormant mouse sperm surgically extracted fr
Externí odkaz:
https://doaj.org/article/bf9504cd7458481db05ef83880ae9942
Autor:
Natalya N Pavlova, Bryan King, Rachel H Josselsohn, Sara Violante, Victoria L Macera, Santosha A Vardhana, Justin R Cross, Craig B Thompson
Publikováno v:
eLife, Vol 9 (2020)
An inadequate supply of amino acids leads to accumulation of uncharged tRNAs, which can bind and activate GCN2 kinase to reduce translation. Here, we show that glutamine-specific tRNAs selectively become uncharged when extracellular amino acid availa
Externí odkaz:
https://doaj.org/article/c0e10590233a43bb8289ff88a95f070b
Autor:
Mina L. Heacock, Evana N. Abdulaziz, Xingxiu Pan, Austin L. Zuckerman, Sara Violante, Canglin Yao, Justin R. Cross, Valentin Cracan
Impaired reduction/oxidation (redox) metabolism is a key contributor to the etiology of many diseases, including primary mitochondrial disorders, cancer, neurodegeneration, and aging. However, mechanistic studies of redox imbalance remain challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3c0aea0d5c0f08b3a09f25f9977e6c
https://doi.org/10.1101/2022.09.20.508785
https://doi.org/10.1101/2022.09.20.508785
Autor:
Hana Andrlová, Oriana Miltiadous, Anastasia I. Kousa, Anqi Dai, Susan DeWolf, Sara Violante, Hee-Yon Park, Sudha Janaki-Raman, Rui Gardner, Sary El Daker, John Slingerland, Paul Giardina, Annelie Clurman, Antonio L. C. Gomes, Chi Nguyen, Marina Burgos da Silva, Gabriel K. Armijo, Nicole Lee, Roberta Zappasodi, Ronan Chaligne, Ignas Masilionis, Emily Fontana, Doris Ponce, Christina Cho, Amy Bush, Lauren Hill, Nelson Chao, Anthony D. Sung, Sergio Giralt, Esther H. Vidal, Kinga K. Hosszu, Sean M. Devlin, Jonathan U. Peled, Justin R. Cross, Miguel-Angel Perales, Dale I. Godfrey, Marcel R. M. van den Brink, Kate A. Markey
Publikováno v:
Sci Transl Med
Microbial diversity is associated with improved outcomes in recipients of allogeneic hematopoietic cell transplantation (allo-HCT), but the mechanism underlying this observation is unclear. In a cohort of 174 patients who underwent allo-HCT, we demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ba4e8238db708b8a855188874d6859
https://doi.org/10.1126/scitranslmed.abj2829
https://doi.org/10.1126/scitranslmed.abj2829
Autor:
Krishna Kadaveru, John Hambor, Clarissa Campbell, Alexander Y. Rudensky, Cheryl Mai, Daniel Konstantinovsky, Peter T. McKenney, Ruben J. Ramos, Olga I Isaeva, Chun-Jun Guo, Michail Schizas, Justin R. Cross, Jacob Verter, Wen-Bing Jin, Sara Violante
Publikováno v:
Nature. 581:475-479
Intestinal health relies on the immunosuppressive activity of CD4+ regulatory T (Treg) cells1. Expression of the transcription factor Foxp3 defines this lineage, and can be induced extrathymically by dietary or commensal-derived antigens in a process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba5447a9b51cd120c59b91735e0d748
https://doi.org/10.1038/s41586-020-2193-0
https://doi.org/10.1038/s41586-020-2193-0
Autor:
Carmen Argmann, Hongjie Chen, Chunli Yu, Tetyana Dodatko, Sander M. Houten, Michelle Puchowicz, Dipankar Bhattacharya, Sara Violante, Scott L. Friedman, Pablo Ranea-Robles
Publikováno v:
Cell Mol Life Sci
Peroxisomes play an essential role in the β-oxidation of dicarboxylic acids (DCAs), which are metabolites formed upon ω-oxidation of fatty acids. Genetic evidence linking transporters and enzymes to specific DCA β-oxidation steps is generally lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754c093387caecb52b1699e91f3ef013
https://europepmc.org/articles/PMC8263512/
https://europepmc.org/articles/PMC8263512/
Autor:
Craig B. Thompson, Sara Violante, Rachel H Josselsohn, Santosha Vardhana, Bryan King, Natalya N. Pavlova, Victoria L Macera, Justin R. Cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0ff34257b0628c7acc89d3760a3c41c
https://doi.org/10.7554/elife.62307.sa2
https://doi.org/10.7554/elife.62307.sa2
Autor:
Craig B. Thompson, Rachel H Josselsohn, Justin R. Cross, Santosha Vardhana, Bryan King, Victoria L Macera, Natalya N. Pavlova, Sara Violante
Publikováno v:
eLife, Vol 9 (2020)
An inadequate supply of amino acids leads to accumulation of uncharged tRNAs, which can bind and activate GCN2 kinase to reduce translation. Here, we show that glutamine-specific tRNAs selectively become uncharged when extracellular amino acid availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166e9c5d526fc99e56ff786cd5f6818e
https://elifesciences.org/articles/62307
https://elifesciences.org/articles/62307
Autor:
Colleen M. Lau, Paolo Giovanelli, Sam Sheppard, Joseph C. Sun, Hyunu Kim, Sara Violante, Endi K. Santosa, Ming Li, Justin R. Cross
Publikováno v:
Cell reports
SUMMARY Natural killer (NK) cells are cytotoxic lymphocytes capable of rapid cytotoxicity, cytokine secretion, and clonal expansion. To sustain such energetically demanding processes, NK cells must increase their metabolic capacity upon activation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798759e86ffc327a750f7637f87a9cec
https://pubmed.ncbi.nlm.nih.gov/34077737
https://pubmed.ncbi.nlm.nih.gov/34077737