Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sara, Szabo"'
MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ
Autor:
Sandra Schrenk, Lindsay J. Bischoff, Jillian Goines, Yuqi Cai, Shruti Vemaraju, Yoshinobu Odaka, Samantha R. Good, Joseph S. Palumbo, Sara Szabo, Damien Reynaud, Catherine D. Van Raamsdonk, Richard A. Lang, Elisa Boscolo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Life-threatening vascular tumors can be associated with uncontrolled activity of the guanine nucleotide-binding protein subunit alpha (Gαq). Here, the authors develop a murine model for these tumors and show that MEK inhibition prevents formation of
Externí odkaz:
https://doaj.org/article/7cad600490c342d6b140a087bcb306ca
Autor:
Jarren R. Oates, Keisuke Sawada, Daniel A. Giles, Pablo C. Alarcon, Michelle S.M.A. Damen, Sara Szabo, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Senad Divanovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammation is a common unifying factor in experimental models of non-alcoholic fatty liver disease (NAFLD) progression. Recent evidence suggests that housing temperature-driven alterations in hepatic inflammation correlate with exacerba
Externí odkaz:
https://doaj.org/article/1f1bb9be755e44ee861e3cade70d99e3
Autor:
Margot A. Lazow, Christine Fuller, Andrew T. Trout, Joseph R. Stanek, Jaime Reuss, Brian K. Turpin, Sara Szabo, Ralph Salloum
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Introduction177Lu-DOTATATE, a radionuclide therapy that binds somatostatin type-2A receptors (SST2A), has demonstrated efficacy in neuroendocrine tumors and evidence of central nervous system (CNS) penetration, supporting potential expansion within p
Externí odkaz:
https://doaj.org/article/60242f28506e4ece8ba94e9bad7c3235
Autor:
Abraham P. Campbell, Lisa Qiu, Jonathan R. Dillman, Andrew T. Trout, Sara Szabo, Oscar F. Lopez–Nunez, Brian S. Pugmire, Andrew H. Schapiro
Publikováno v:
Pediatric Radiology. 53:984-1004
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d690a282b88422e0c040ac7a231f3d8
https://doi.org/10.1007/s00247-023-05636-3
https://doi.org/10.1007/s00247-023-05636-3
Autor:
Youjin Na, Ashley Hall, Yanan Yu, Liang Hu, Kwangmin Choi, Jake A. Burgard, Sara Szabo, Gang Huang, Nancy Ratner, Jianqiang Wu
Publikováno v:
Oncogene
Neurofibromatosis type 1 (NF1) patients are predisposed to develop plexiform neurofibromas (PNFs). Three endoplasmic reticulum (ER) stress response pathways restore cellular homeostasis. The unfolded protein response (UPR) sensors contribute to tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2615e8ed010ab41e6ebba61f8262c57f
https://doi.org/10.1038/s41388-023-02620-x
https://doi.org/10.1038/s41388-023-02620-x
Autor:
Jo Cooke-Barber, Joseph G. Brungardt, Michael Sorger, Joseph G. Pressey, Brian Turpin, Rajaram Nagarajan, Sara Szabo, Joel Sorger, Neil Johnson, Roshni Dasgupta
Publikováno v:
Annals of Surgical Oncology. 30:3658-3665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04b9bf1ea081160cbd4a9e5e320bfabf
https://doi.org/10.1245/s10434-023-13097-z
https://doi.org/10.1245/s10434-023-13097-z
Autor:
Laura Conforti, Laura Agresta, Maria Lehn, Kristin Lampe, Rachel Cantrell, Cassandra Hennies, Sara Szabo, Trisha Wise-Draper, Kasper Hoebe, Edith M Janssen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Developing novel strategies to overcome the immunosuppressive tumor microenvironment is a critically important area of cancer therapy research. Here, we assess the therapeutic potential of CD244 (2B4/signaling lymphocyte activation molecul
Externí odkaz:
https://doaj.org/article/399509727da14162bd5e3fe439ed4134
Publikováno v:
Pediatric Radiology. 53:28-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb908bc8a5ea486f82753524eb851203
https://doi.org/10.1007/s00247-022-05450-3
https://doi.org/10.1007/s00247-022-05450-3
Autor:
Rashmi S. Hegde, Joseph G. Pressey, Sara Szabo, Tanya V. Kalin, David Milewski, Kaushik Roychoudhury, Ram Naresh Pandey, Yuhua Wang
Figure S3 documents how loss of Eya3 or BZ treatment affects multicellular tumor spheroids generated with A673 and RD-ES cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e94d198ec96e9ff91b49bb355f263f0
https://doi.org/10.1158/1535-7163.22522564.v1
https://doi.org/10.1158/1535-7163.22522564.v1
Autor:
Rashmi S. Hegde, Joseph G. Pressey, Sara Szabo, Tanya V. Kalin, David Milewski, Kaushik Roychoudhury, Ram Naresh Pandey, Yuhua Wang
EWSR1/FLI1, the most common fusion gene in Ewing sarcoma, upregulates expression of the Eyes Absent 3 (EYA3) transactivator–phosphatase protein. The purpose of this study was to investigate molecular and cellular mechanisms through which EYA3 might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b437ac795ba27d24d211c13a3719b8
https://doi.org/10.1158/1535-7163.c.6543436
https://doi.org/10.1158/1535-7163.c.6543436