Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sara, Shum"'
Autor:
Tomoki Imaoka, Weize Huang, Sara Shum, Dale W. Hailey, Shih-Yu Chang, Alenka Chapron, Catherine K. Yeung, Jonathan Himmelfarb, Nina Isoherranen, Edward J. Kelly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Opioid overdose, dependence, and addiction are a major public health crisis. Patients with chronic kidney disease (CKD) are at high risk of opioid overdose, therefore novel methods that provide accurate prediction of renal clearance (CLr) an
Externí odkaz:
https://doaj.org/article/db5ac2fbd58248ce8a1251ee6b9e7c7a
Autor:
Sara Shum, Jay S. Kirkwood, Jing Jing, Rebekah Petroff, Brenda Crouthamel, Kimberly S. Grant, Thomas M. Burbacher, Wendel L. Nelson, Nina Isoherranen
Publikováno v:
ACS Omega, Vol 3, Iss 9, Pp 12079-12088 (2018)
Externí odkaz:
https://doaj.org/article/4be5f743fea1463b99e6f4e78a051575
Autor:
Ogochukwu U, Amaeze, Lindsay C, Czuba, Aprajita S, Yadav, Emily E, Fay, Jeffrey, LaFrance, Sara, Shum, Sue L, Moreni, Jennie, Mao, Weize, Huang, Nina, Isoherranen, Mary F, Hebert
Publikováno v:
J Clin Pharmacol
The mechanism of cytochrome P450 2D6 (CYP2D6) induction during pregnancy has not been evaluated in humans. This study assessed the changes in CYP2D6 and CYP3A activities during pregnancy and postpartum, and the effect of vitamin A administration on C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e79fc90530165de4c9a35f2d815d41
https://doi.org/10.1002/jcph.2169
https://doi.org/10.1002/jcph.2169
Autor:
Andrea Bauer, Philippe Berben, Sudhir S. Chakravarthi, Sayantan Chattorraj, Ashish Garg, Betty Gourdon, Tycho Heimbach, Ye Huang, Christopher Morrison, Deepak Mundhra, Ramesh Palaparthy, Pratik Saha, Maxime Siemons, Naveed A. Shaik, Yi Shi, Sara Shum, Naveen K. Thakral, Shweta Urva, Ryan Vargo, Venkat R. Koganti, Stephanie E. Barrett
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3930deded7f88a1948c914b914796267
https://doi.org/10.1007/s11095-022-03391-y
https://doi.org/10.1007/s11095-022-03391-y
Autor:
Rebekah L. Petroff, Christopher Williams, Jian-Liang Li, James W. MacDonald, Theo K. Bammler, Todd Richards, Christopher N. English, Audrey Baldessari, Sara Shum, Jing Jing, Nina Isoherranen, Brenda Crouthamel, Noelle McKain, Kimberly S. Grant, Thomas M. Burbacher, G. Jean Harry
Publikováno v:
Environmental Health Perspectives. 130
The excitotoxic molecule, domoic acid (DA), is a marine algal toxin known to induce overt hippocampal neurotoxicity. Recent experimental and epidemiological studies suggest adverse neurological effects at exposure levels near the current regulatory l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c73527b2ffb4e5f6af9458d83cd786
https://doi.org/10.1289/ehp10923
https://doi.org/10.1289/ehp10923
Autor:
Kathi A. Lefebvre, Betsy Jean Yakes, Elizabeth Frame, Preston Kendrick, Sara Shum, Nina Isoherranen, Bridget E. Ferriss, Alison Robertson, Alicia Hendrix, David J. Marcinek, Lynn Grattan
Publikováno v:
Toxins, Vol 11, Iss 5, p 293 (2019)
Domoic acid (DA)-producing harmful algal blooms (HABs) have been present at unprecedented geographic extent and duration in recent years causing an increase in contamination of seafood by this common environmental neurotoxin. The toxin is responsible
Externí odkaz:
https://doaj.org/article/0264d3a45d4b439b892c469426d26c7b
Autor:
Lindsay C. Czuba, Emily E. Fay, Jeffrey LaFrance, Chase K. Smith, Sara Shum, Sue L. Moreni, Jennie Mao, Nina Isoherranen, Mary F. Hebert
Publikováno v:
Nutrients; Volume 14; Issue 7; Pages: 1365
Vitamin A is vital to maternal–fetal health and pregnancy outcomes. However, little is known about pregnancy associated changes in maternal vitamin A homeostasis and concentrations of circulating retinol metabolites. The goal of this study was to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af792d152b54ff3020df2ae4a57b2b3e
https://pubmed.ncbi.nlm.nih.gov/35405978
https://pubmed.ncbi.nlm.nih.gov/35405978
Autor:
Alyssa Stephenson-Famy, Lindsay C. Czuba, Emily E. Fay, Sara Shum, Nina Isoherranen, Jennifer E Sager
Publikováno v:
Ther Drug Monit
Background Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP (OH-BUP), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf6258f094689ecf6723b8333cb7286
https://europepmc.org/articles/PMC8426418/
https://europepmc.org/articles/PMC8426418/
Autor:
Shih-Yu Chang, Jonathan Himmelfarb, Edward J. Kelly, Weize Huang, Tomoki Imaoka, Dale W. Hailey, Catherine K. Yeung, Sara Shum, Nina Isoherranen, Alenka Chapron
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Opioid overdose, dependence, and addiction are a major public health crisis. Patients with chronic kidney disease (CKD) are at high risk of opioid overdose, therefore novel methods that provide accurate prediction of renal clearance (CLr) and systemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd08bedf8417b6ead725ec357fd98b1c
https://doi.org/10.1038/s41598-021-00338-y
https://doi.org/10.1038/s41598-021-00338-y
Autor:
Courtney Stanley, Kimberly S. Grant, Nina Isoherranen, Brenda Crouthamel, Rebekah Petroff, Sara Shum, Jing Jing, Noelle McKain, Thomas M. Burbacher
Publikováno v:
Neurotoxicology and Teratology. 72:10-21
Domoic Acid (DA) is a naturally-occurring excitotoxin, produced by marine algae, which can bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is associated with gastrointestinal illness that, in the case of high D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474b438929067a9ad24c15011e1d9753
https://doi.org/10.1016/j.ntt.2019.01.001
https://doi.org/10.1016/j.ntt.2019.01.001