Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sara, Sharifpoor"'
Autor:
Amy Huei-Yi Lee, D. Patrick Bastedo, Ji-Young Youn, Timothy Lo, Maggie A. Middleton, Inga Kireeva, Jee Yeon Lee, Sara Sharifpoor, Anastasia Baryshnikova, Jianfeng Zhang, Pauline W. Wang, Sergio G. Peisajovich, Michael Constanzo, Brenda J. Andrews, Charles M. Boone, Darrell Desveaux, David S. Guttman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 2, Pp 535-547 (2019)
Gram-negative bacterial pathogens inject type III secreted effectors (T3SEs) directly into host cells to promote pathogen fitness by manipulating host cellular processes. Despite their crucial role in promoting virulence, relatively few T3SEs have we
Externí odkaz:
https://doaj.org/article/1b9e884404934edc985db608a85c9aac
Autor:
Amy Huei-Yi, Lee, D Patrick, Bastedo, Ji-Young, Youn, Timothy, Lo, Maggie A, Middleton, Inga, Kireeva, Jee Yeon, Lee, Sara, Sharifpoor, Anastasia, Baryshnikova, Jianfeng, Zhang, Pauline W, Wang, Sergio G, Peisajovich, Michael, Constanzo, Brenda J, Andrews, Charles M, Boone, Darrell, Desveaux, David S, Guttman
Publikováno v:
G3: Genes|Genomes|Genetics
Gram-negative bacterial pathogens inject type III secreted effectors (T3SEs) directly into host cells to promote pathogen fitness by manipulating host cellular processes. Despite their crucial role in promoting virulence, relatively few T3SEs have we
Autor:
D. Patrick Bastedo, David S. Guttman, Inga Kireeva, Charles Boone, Brenda J. Andrews, Michael Constanzo, Jee Yeon Lee, Timothy Lo, Pauline W. Wang, M A Middleton, Darrell Desveaux, Sergio G. Peisajovich, Amy S. Lee, Sara Sharifpoor, Jianfeng Zhang, Ji-Young Youn, Anastasia Baryshnikova
Gram-negative bacterial pathogens inject type III secreted effectors (T3SEs) directly into host cells to promote pathogen fitness by manipulating host cellular processes. Despite their crucial role in promoting virulence, relatively few T3SEs have we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1153c138e16589bfbdf924090dc208a6
Autor:
Carles Pons, Julia Hanchard, Hongwei Zhu, Daniel I. Bolnick, Brenda J. Andrews, Bryan Joseph San Luis, Elena Kuzmin, Matej Usaj, Michael Costanzo, Robbie Loewith, Wen Wang, Kaicong Xu, Amy A. Caudy, Michael Pryszlak, Chad L. Myers, Sara Sharifpoor, Yiqun Chen, Elizabeth N. Koch, Andrius J. Dagilis, Nydia Van Dyk, Benjamin VanderSluis, Margot Riggi, Guihong Tan, Ermira Shuteriqi, Mojca Mattiazzi Usaj, Raamesh Deshpande, Hamed Heydari, Attila Balint, Jason Zi Yang Wang, Charles Boone, Jolanda van Leeuwen, Grant W. Brown
Publikováno v:
Science (New York, N.Y.). 360(6386)
INTRODUCTION Genetic interactions occur when mutations in different genes combine to result in a phenotype that is different from expectation based on those of the individual mutations. Negative genetic interactions occur when a combination of mutati
Autor:
Anu Surendra, Brenda J. Andrews, Lawrence E. Heisler, Alison C Douglas, Zhun Yan, Guri Giaever, Andrew M. Smith, Sara Sharifpoor, Owen Ryan, Dewald van Dyk, Anna Y. Lee, Tanja Durbic, Corey Nislow, Charles Boone, Hendrikje Göttert
Publikováno v:
G3: Genes|Genomes|Genetics
Systematic analysis of gene overexpression phenotypes provides an insight into gene function, enzyme targets, and biological pathways. Here, we describe a novel functional genomics platform that enables a highly parallel and systematic assessment of
Autor:
Brenda J. Andrews, Michael Costanzo, Anastasia Baryshnikova, Charles Boone, Benjamin VanderSluis, Alison C Douglas, Helena Friesen, Chad L. Myers, Balázs Papp, Dewald van Dyk, Ji-Young Youn, Sara Sharifpoor
Publikováno v:
Genome Research. 22:791-801
A combinatorial genetic perturbation strategy was applied to interrogate the yeast kinome on a genome-wide scale. We assessed the global effects of gene overexpression or gene deletion to map an integrated genetic interaction network of synthetic dos
Autor:
Elena, Kuzmin, Sara, Sharifpoor, Anastasia, Baryshnikova, Michael, Costanzo, Chad L, Myers, Brenda J, Andrews, Charles, Boone
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1205
Genetic interactions occur when mutant alleles of two or more genes collaborate to generate an unusual composite phenotype, one that would not be predicted based on the expected combined effects of the individual mutant alleles. Synthetic Genetic Arr
Autor:
Sara Sharifpoor, Brenda J. Andrews, Charles Boone, Anastasia Baryshnikova, Chad L. Myers, Michael Costanzo, Elena Kuzmin
Publikováno v:
Methods in Molecular Biology ISBN: 9781493913626
Genetic interactions occur when mutant alleles of two or more genes collaborate to generate an unusual composite phenotype, one that would not be predicted based on the expected combined effects of the individual mutant alleles. Synthetic Genetic Arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b536a05697cbaf3175050362ebd22bcf
https://doi.org/10.1007/978-1-4939-1363-3_10
https://doi.org/10.1007/978-1-4939-1363-3_10
Autor:
Norbert Perrimon, Ralph A. Neumüller, Anastasia Samsonova, Yanhui Hu, Karen Founk, Brenda J. Andrews, Michael Buckner, Sara Sharifpoor, Fred Winston, Arunachalam Vinayagam, Adam P. Rosebrock, Thomas Gross
Publikováno v:
Science Signaling. 6
Regulation of cell growth is a fundamental process in development and disease that integrates a vast array of extra- and intracellular information. A central player in this process is RNA polymerase I (Pol I), which transcribes ribosomal RNA (rRNA) g
Autor:
Yizhao Tan, Natasha Pascoe, Elena Kuzmin, Carles Pons, Scott W. Simpkins, Maximilian Billmann, Matej Usaj, Jolanda van Leeuwen, Olga G. Troyanskaya, Zhen Yuan Lin, Erin B. Styles, Sara Sharifpoor, Bryan Joseph San Luis, Noël Malod-Dognin, Julia Hanchard, Claire Moore, Brenda J. Andrews, Igor Stagljar, Vuk Janjić, Anastasia Baryshnikova, Michael Costanzo, Susan D. Lee, Anne-Claude Gingras, Yiqun Chen, Chad L. Myers, Charles Boone, Sondra Bahr, Harsha Garadi Suresh, Benjamin VanderSluis, Jeff S. Piotrowski, Guihong Tan, Natasa Przulj, Jamie Snider, Emira Shuteriqi, Michael Boutros, Raamesh Deshpande, Adam P. Rosebrock, Christoph F. Kurat, Lars M. Steinmetz, Tharan Srikumar, Brian Raught, Wen Wang, Hiroki Okada, Justin Nelson, Sheena C. Li, Hongwei Zhu, Yoshikazu Ohya, Tian Xia, Zhijian Li, Nydia Van Dyk, Elizabeth N. Koch, Vicent Pelechano, Amy A. Caudy, Mojca Mattiazzi Usaj
Publikováno v:
Scopus-Elsevier
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic interaction occurs when two mutations, neither lethal individually, combine to ca