Zobrazeno 1 - 10 of 44 pro vyhledávání: '"Sara, Sattin"'
1
Akademický článek
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist.
Autor: Michel Thépaut, Joanna Luczkowiak, Corinne Vivès, Nuria Labiod, Isabelle Bally, Fátima Lasala, Yasmina Grimoire, Daphna Fenel, Sara Sattin, Nicole Thielens, Guy Schoehn, Anna Bernardi, Rafael Delgado, Franck Fieschi
Publikováno v: PLoS Pathogens, Vol 17, Iss 5, p e1009576 (2021)
The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history. Despite early identification of ACE2 as the receptor for viral spike protein, much remains to be understood about the molecular events behind viral dissemination. We
Externí odkaz: https://doaj.org/article/2dab28ce226f4cd4ba786236d8f23229
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2
Akademický článek
Homology Model of a Catalytically Competent Bifunctional Rel Protein
Autor: Monica Civera, Sara Sattin
Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)
Bacteria have developed different bet hedging strategies to survive hostile environments and stressful conditions with persistency being maybe the most elegant yet still poorly understood one. Persisters’ temporary tolerance to antibiotic treatment
Externí odkaz: https://doaj.org/article/665d90d587ae4aa5863d3a7ee26b0124
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3
Akademický článek
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Autor: Crescenzo Coppa, Luca Sorrentino, Monica Civera, Marco Minneci, Francesca Vasile, Sara Sattin
Publikováno v: Molecules, Vol 27, Iss 10, p 3097 (2022)
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such
Externí odkaz: https://doaj.org/article/1f1274a59fe44197b3929f2e7386b8a6
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4
Akademický článek
Behavior of glycolylated sialoglycans in the binding pockets of murine and human CD22
Autor: Cristina Di Carluccio, Rosa Ester Forgione, Marco Montefiori, Monica Civera, Sara Sattin, Giovanni Smaldone, K. Fukase, Y. Manabe, Paul R. Crocker, Antonio Molinaro, Roberta Marchetti, Alba Silipo
Publikováno v: iScience, Vol 24, Iss 1, Pp 101998- (2021)
Summary: Siglecs (sialic acid binding immunoglobulin (Ig)-like lectins) constitute a group of 15 human and 9 murine cell-surface transmembrane receptors belonging to the I-type lectin family, mostly expressed on innate immune cells and characterized
Externí odkaz: https://doaj.org/article/a235801d51084937ad1d3362512574e7
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5
Akademický článek
Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell
Autor: Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G. Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M. Apaja, Sara Sattin, Lenore K. Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C. Young, Gergely L. Lukacs
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The F508 deletion (F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR) is the most common CF causing mutation. Here the authors show that cytosolic chaperones shift the F508del channel conformation to the native fold by kinetic
Externí odkaz: https://doaj.org/article/e14a35b0276c400f88eedbb10dd40d9d
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6
Chemical and Biophysical Approaches to Allosteric Modulation
Autor: Francesca Vasile, Monica Civera, Sara Sattin, Luca Sorrentino, Elisabetta Moroni
Publikováno v: European journal of organic chemistry (Online) 2021 (2021): 4245–4259. doi:10.1002/ejoc.202100506
info:cnr-pdr/source/autori:Civera M.; Moroni E.; Sorrentino L.; Vasile F.; Sattin S./titolo:Chemical and Biophysical Approaches to Allosteric Modulation/doi:10.1002%2Fejoc.202100506/rivista:European journal of organic chemistry (Online)/anno:2021/pagina_da:4245/pagina_a:4259/intervallo_pagine:4245–4259/volume:2021
Allosteric regulation, i. e. the control exerted on an orthosteric site by an effector interacting at a distinct and distant site, represents a prime example of a precise tuning system of several key biological processes like gene transcription, cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31790f55ca57c384672215f8df7d846
https://doi.org/10.1002/ejoc.202100506
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7
Akademický článek
Pseudo-Mannosylated DC-SIGN Ligands as Potential Adjuvants for HIV Vaccines
Autor: Angela Berzi, Norbert Varga, Sara Sattin, Patrizio Antonazzo, Mara Biasin, Irene Cetin, Daria Trabattoni, Anna Bernardi, Mario Clerici
Publikováno v: Viruses, Vol 6, Iss 2, Pp 391-403 (2014)
The development of new and effective adjuvants may play a fundamental role in improving HIV vaccine efficacy. New classes of vaccine adjuvants activate innate immunity receptors, notably toll like receptors (TLRs). Adjuvants targeting the C-Type lect
Externí odkaz: https://doaj.org/article/0934852c1147432aa83ee498bb1f9729
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10
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
Autor: Daphna Fenel, Fátima Lasala, Anna Bernardi, Guy Schoehn, Michel Thépaut, Joanna Luczkowiak, Rafael L. Delgado, Isabelle Bally, Sara Sattin, Franck Fieschi, Nicole M. Thielens, Corinne Vivès, Yasmina Grimoire, Nuria Labiod
Publikováno v: PLoS Pathogens
PLoS Pathogens, 2021, 17 (5), pp.e1009576. ⟨10.1101/2020.08.09.242917⟩
PLoS Pathogens, Public Library of Science, 2021, 17 (5), pp.e1009576. ⟨10.1101/2020.08.09.242917⟩
PLoS Pathogens, Vol 17, Iss 5, p e1009576 (2021)
bioRxiv
The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history. Despite early identification of ACE2 as the receptor for viral spike protein, much remains to be understood about the molecular events behind viral dissemination. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240adde67db87a73f1f9c9340a1dfc2d
https://hal.univ-grenoble-alpes.fr/hal-02947771
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