Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Sara, Pagani"'
Autor:
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E. Church, Briana M. Hudson, Frances Humby, Michele Bombardieri, Myles J. Lewis, Costantino Pitzalis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with RA matched for disease stage and treatment exposure, we assessed how Axl and MerT
Externí odkaz:
https://doaj.org/article/479b8ed47d1c4eb09e9de80de7cc33ef
Autor:
Sara Pagani, Valeria Calcaterra, Gloria Acquafredda, Chiara Montalbano, Elena Bozzola, Pietro Ferrara, Manuela Gasparri, Alberto Villani, Mauro Bozzola
Publikováno v:
Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-6 (2020)
Abstract Background Pubertal timing is known to be influenced by interactions among various genetic, nutritional, environmental and socio-economic factors, although the ultimate mechanisms underlying the increase in pulsatile GnRH secretion at pubert
Externí odkaz:
https://doaj.org/article/ff986b8f444d4d8cad34a3d9d483c3c1
Autor:
Mathieu Ferrari, Shimobi C. Onuoha, Liliane Fossati-Jimack, Alessandra Nerviani, Pedro L. Alves, Sara Pagani, Cecilia Deantonio, Federico Colombo, Claudio Santoro, Daniele Sblattero, Costantino Pitzalis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Biologic drugs, especially anti-TNF, are considered as the gold standard therapy in rheumatoid arthritis. However, non-uniform efficacy, incidence of infections, and high costs are major concerns. Novel tissue-specific agents may overcome the current
Externí odkaz:
https://doaj.org/article/8e51988c2b5b4d63861b2b90547439fa
Publikováno v:
Italian Journal of Pediatrics, Vol 43, Iss 1, Pp 1-8 (2017)
Abstract Referral for an assessment of tall stature is less common than for short stature. Tall stature is defined as a height more than two standard deviations above the mean for age. The majority of subjects with tall stature show a familial tall s
Externí odkaz:
https://doaj.org/article/9c1e36b19bd64f2eb26ed0c28f669368
Autor:
Mauro Bozzola, Cristina Meazza, Chiara Gertosio, Sara Pagani, Daniela Larizza, Valeria Calcaterra, Ombretta Luinetti, Giovanni Farello, Carmine Tinelli, Lorenzo Iughetti
Publikováno v:
Italian Journal of Pediatrics, Vol 43, Iss 1, Pp 1-5 (2017)
Abstract Background The aim of our study is to evaluate if in children with highly positive serology and HLA-DQ2/DQ8 (triple test, TT) and only extra-intestinal symptoms, it is possible to omit performing an intestinal biopsy for celiac disease (CD)
Externí odkaz:
https://doaj.org/article/1fada2fc574d415196421bc58985781c
Autor:
Daniele Mauro, Sotiria Manou-Stathopoulou, Felice Rivellese, Elisabetta Sciacca, Katriona Goldmann, Victoria Tsang, Isabelle Lucey-Clayton, Sara Pagani, Farah Alam, Debasish Pyne, Ravindra Rajakariar, Patrick A. Gordon, James Whiteford, Michele Bombardieri, Costantino Pitzalis, Myles J. Lewis
Both TLR7 and NF-κB hyperactivity are known to contribute to pathogenesis in Systemic Lupus Erythematosus (SLE), driving a pro-interferon response, autoreactive B cell expansion and autoantibody production. UBE2L3 is an SLE susceptibility gene which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9bdde59abad2b159ae116918180b785
https://hdl.handle.net/11591/499910
https://hdl.handle.net/11591/499910
Autor:
Sara Pagani, Elena Bozzola, Caterina Strisciuglio, Cristina Meazza, Erasmo Miele, M. Malamisura, Paola De Angelis, Mauro Bozzola
Publikováno v:
Frontiers in Pediatrics, Vol 6 (2018)
Background: We proposed to verify the role of growth hormone receptor gene expression in growth failure of children with Crohn's disease (CD).Methods: We measured serum levels of growth hormone binding protein (GHBP) and insulin-like growth factor-I
Externí odkaz:
https://doaj.org/article/9248ca7db7734e4caaaa938123e426c7
Autor:
Alberto Villani, Gloria Acquafredda, Manuela Gasparri, Chiara Montalbano, Sara Pagani, Pietro Ferrara, Mauro Bozzola, Valeria Calcaterra, Elena Bozzola
Publikováno v:
Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-6 (2020)
Italian Journal of Pediatrics
Italian Journal of Pediatrics
Background Pubertal timing is known to be influenced by interactions among various genetic, nutritional, environmental and socio-economic factors, although the ultimate mechanisms underlying the increase in pulsatile GnRH secretion at puberty have ye
Growth hormone receptor polymorphisms and growth hormone response to stimulation test: a pilot study
Autor:
Giulia Genoni, Gianpaolo De Filippo, Cristina Meazza, Sara Pagani, Mauro Bozzola, Gianni Bona, Domenico Rendina, Elena Bozzola
Publikováno v:
Minerva Pediatrics. 73
BACKGROUND No gold standard pharmacological stimulation test exists for the diagnosis of growth hormone deficiency (GHD). In addition, the genetic factors that influence growth hormone (GH) responses remain unclear. This study aimed to determine whet
Autor:
Elena Bozzola, Sara Pagani, Valeria Raia, Fabio Majo, Mauro Bozzola, Vito Terlizzi, Gloria Acquafredda, Alberto Villani
Publikováno v:
Clinical Medicine & Research. 17:82-89
OBJECTIVE: To verify whether growth hormone receptor (GHR) gene expression plays a role in growth of children with cystic fibrosis (CF), as a consequence of the chronic inflammatory condition and malnutrition. DESIGN: We enrolled 49 prepubertal patie