Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara, Nejat"'
Autor:
Bethany L. MacLeod, W. Xu, Giselle Boukhaled, Sabelo Lukhele, Diala Abd-Rabbo, Mengdi Guo, Laura M. Snell, Sara Nejat, Heidi Elsaesser, Tracy L. McGaha, Slava Epelman, Kebria Hezaveh, David G. Brooks, Ramanandan Prabhakaran, Nirmin Alsahafi
Publikováno v:
Nature Immunology. 22:1524-1537
Inhibiting PD-1:PD-L1 signaling has transformed therapeutic immune restoration. CD4+ T cells sustain immunity in chronic infections and cancer, yet little is known about how PD-1 signaling modulates CD4+ helper T (TH) cell responses or the ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4003e48e6cfcf2bf99d001784cba3781
https://doi.org/10.1038/s41590-021-01060-7
https://doi.org/10.1038/s41590-021-01060-7
Autor:
Sarah A. Dick, Anthony Wong, Homaira Hamidzada, Sara Nejat, Robert Nechanitzky, Shabana Vohra, Brigitte Mueller, Rysa Zaman, Crystal Kantores, Laura Aronoff, Abdul Momen, Duygu Nechanitzky, Wanda Y. Li, Parameswaran Ramachandran, Sarah Q. Crome, Burkhard Becher, Myron I. Cybulsky, Filio Billia, Shaf Keshavjee, Seema Mital, Clint S. Robbins, Tak W. Mak, Slava Epelman
Publikováno v:
Science Immunology. 7
Resident macrophages orchestrate homeostatic, inflammatory, and reparative activities. It is appreciated that different tissues instruct specialized macrophage functions. However, individual tissues contain heterogeneous subpopulations, and how these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3020bfb5ad90e5f99c75ec08329283af
https://doi.org/10.1126/sciimmunol.abf7777
https://doi.org/10.1126/sciimmunol.abf7777
Autor:
Michael H Ngo, Joanna Borowska-Fielding, Godfrey Heathcote, Sara Nejat, Melanie E Kelly, Christopher R McMaster, Johane M Robitaille
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0158320 (2016)
Mutations in genes that code for components of the Norrin-FZD4 ligand-receptor complex cause the inherited childhood blinding disorder familial exudative vitreoretinopathy (FEVR). Statistical evidence from studies of patients at risk for the acquired
Externí odkaz:
https://doaj.org/article/2c02dad2af0b47a1b2910246e0a0dc0e
Autor:
Laura M, Snell, Wenxi, Xu, Diala, Abd-Rabbo, Giselle, Boukhaled, Mengdi, Guo, Bethany L, Macleod, Heidi J, Elsaesser, Kebria, Hezaveh, Nirmin, Alsahafi, Sabelo, Lukhele, Sara, Nejat, Ramanandan, Prabhakaran, Slava, Epelman, Tracy L, McGaha, David G, Brooks
Publikováno v:
Nat Immunol
Inhibiting PD-1:PD-L1 signaling has transformed therapeutic immune restoration. CD4(+) T cells sustain immunity in chronic infections and cancer, yet little is known about how PD-1 signaling modulates CD4(+) helper T (T(H)) cell responses or the abil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::828b63e1cb80f691d1a66c712b315fa5
https://pubmed.ncbi.nlm.nih.gov/34795443
https://pubmed.ncbi.nlm.nih.gov/34795443
Autor:
Myron I. Cybulsky, Xavier Clemente-Casares, Rickvinder Besla, Sarah A. Dick, Jinmiao Chen, Sara Nejat, Rysa Zaman, Jillian A. Macklin, Abdul Momen, Anthony Wong, Siyavash Hosseinzadeh, Laura Aronoff, Slava Epelman, Crystal Kantores, Marwan G. Althagafi, Florent Ginhoux, Kory J. Lavine, Babak Razani, Mansoor Husain, Clinton S. Robbins, Iulia Barbu
Publikováno v:
Nature immunology
Macrophages promote both injury and repair after myocardial infarction, but discriminating functions within mixed populations remains challenging. Here we used fate mapping, parabiosis and single-cell transcriptomics to demonstrate that at steady sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa50154c1df0e7800bb991f4815f21a
http://europepmc.org/articles/PMC6565365
http://europepmc.org/articles/PMC6565365
Autor:
Sara Nejat, Sarah A. Dick, Crystal Kantores, Abdul Momen, Kory J. Lavine, Filio Billia, Laura Aronoff, Yiming Wang, Seema Mital, Homaira Hamidzada, Anthony Wong, Babak Razani, Slava Epelman, Rysa Zaman, Julia Lin
Publikováno v:
Xenotransplantation
Post-transplantation cardiac xenograft growth in an orthotopic pig to baboon model is a life-limiting phenomenon that is poorly understood. Possible causes of growth include both intrinsic and extrinsic etiologies. Extrinsic causes are thought to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1aad161fc1aa36da529e5730c917f1
https://doi.org/10.1016/j.immuni.2021.07.006
https://doi.org/10.1016/j.immuni.2021.07.006
Autor:
Siyavash Hosseinzadeh, Anthony Wong, Laura Aronoff, Myron I. Cybulsky, Babak Razani, Abdul Momen, Rysa Zaman, Crystal Kantores, Sarah A. Dick, Clinton S. Robbins, Mansoor Husain, Florent Ginhoux, Jinmiao Chen, Iulia Barbu, Slava Epelman, Kory J. Lavine, Sara Nejat, Rickvinder Besla, Marwan G. Althagafi, Jillian A. Macklin, Xavier Clemente-Casares
Publikováno v:
Nature Immunology. 20:664-664
In the version of this article initially published, the equal contribution of the third author was omitted. The footnote links for that author should be "Sara Nejat1,11" and the correct statement is as follows: "11These authors contributed equally: S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62fc3ad15f56d0e19c0a4126de3e87e2
https://doi.org/10.1038/s41590-019-0363-8
https://doi.org/10.1038/s41590-019-0363-8
Publikováno v:
Transplant Immunology. 19:103-111
We have developed a model of aortic allograft vasculopathy (AV) that uses mouse strains that are fully disparate at Class I, Class II and minor histocompatibility antigens. Acute rejection is ablated with therapeutic doses of the calcineurin inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7992e6616cfdaca316d6c1f32c519ab
https://doi.org/10.1016/j.trim.2008.03.003
https://doi.org/10.1016/j.trim.2008.03.003
Publikováno v:
Transplant Immunology. 19:120-126
The respective roles of the endothelium and the media as allo-immune targets in the generation of allograft vasculopathy (AV) have yet to be clearly defined. Although endothelial damage has been implicated in the progression of AV, evidence from mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28465dc54df0839ef98751f2c669efe1
https://doi.org/10.1016/j.trim.2008.03.002
https://doi.org/10.1016/j.trim.2008.03.002
Publikováno v:
International Congress Series. 1262:486-489
Collagens in the extracellular matrix play important roles modulating the vascular response to injury during the progression of atherosclerosis and restenosis. Collagen can regulate smooth muscle cell (SMC) proliferation, and SMC and macrophage migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3207b2b537772b4b6b9e2433243203
https://doi.org/10.1016/j.ics.2003.12.021
https://doi.org/10.1016/j.ics.2003.12.021