Zobrazeno 1 - 10 of 61 pro vyhledávání: '"Sara, Llames"'
1
Akademický článek
In-stent restenosis is associated with proliferative skin healing and specific immune and endothelial cell profiles: results from the RACHEL trial
Autor: Íñigo Lozano, Roi Bangueses, Isabel Rodríguez, Marta Pevida, Raúl Rodríguez-Aguilar, Diana Rodríguez, Martina Espasandín-Arias, Sara Llames, Álvaro Meana, Ana Suárez, Javier Rodríguez-Carrio
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionIn-stent restenosis (ISR) is a major challenge in interventional cardiology. Both ISR and excessive skin healing are aberrant hyperplasic responses, which may be functionally related. However, the cellular component underlying ISR remains
Externí odkaz: https://doaj.org/article/24210e6e02c44c00978215714655d77a
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2
Akademický článek
Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome
Autor: Victoria Gálvez, Esteban Chacón-Solano, Jose Bonafont, Ángeles Mencía, Wei-Li Di, Rodolfo Murillas, Sara Llames, Asunción Vicente, Marcela Del Rio, Marta Carretero, Fernando Larcher
Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 280-290 (2020)
Current efforts to find specific genodermatoses treatments and define precise pathogenesis mechanisms require appropriate surrogate models with human cells. Although transgenic and gene knockout mouse models for several of these disorders exist, they
Externí odkaz: https://doaj.org/article/d75b071d40cb45b5b8edf78f7f767001
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3
Akademický článek
Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy
Autor: Manuel Chacón, Natalia Vázquez, Sergio Alonso-Alonso, Mairobi Persinal-Medina, Sara Llames, Marta Pevida, Ignacio Alcalde, Jesús Merayo-Lloves, Álvaro Meana
Publikováno v: Biosensors, Vol 13, Iss 2, p 162 (2023)
The rabbit skin irritation test has been the standard for evaluating the irritation potential of chemicals; however, alternative methods that do not use animal testing are actively encouraged. Reconstructed human epidermis (RhE) models mimic the bioc
Externí odkaz: https://doaj.org/article/88f241f30a1f453191ffbd05790260ff
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4
Akademický článek
DNA Repair and Immune Response Pathways Are Deregulated in Melanocyte-Keratinocyte Co-cultures Derived From the Healthy Skin of Familial Melanoma Patients
Autor: Miriam Potrony, Tariq Sami Haddad, Gemma Tell-Martí, Pol Gimenez-Xavier, Carlos Leon, Marta Pevida, Judit Mateu, Celia Badenas, Cristina Carrera, Josep Malvehy, Paula Aguilera, Sara Llames, Maria José Escámez, Joan A. Puig-Butillé, Marcela del Río, Susana Puig
Publikováno v: Frontiers in Medicine, Vol 8 (2021)
Familial melanoma accounts for 10% of cases, being CDKN2A the main high-risk gene. However, the mechanisms underlying melanomagenesis in these cases remain poorly understood. Our aim was to analyze the transcriptome of melanocyte-keratinocyte co-cult
Externí odkaz: https://doaj.org/article/a850c7da79184016a1d494670bb72606
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7
Polymerizable Skin Hydrogel for Full Thickness Wound Healing
Autor: Mairobi Persinal-Medina, Sara Llames, Manuel Chacón, Natalia Vázquez, Marta Pevida, Ignacio Alcalde, Sergio Alonso-Alonso, Laura María Martínez-López, Jesús Merayo-Lloves, Álvaro Meana
Publikováno v: Scopus
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4837
The skin is the largest organ in the human body, comprising the main barrier against the environment. When the skin loses its integrity, it is critical to replace it to prevent water loss and the proliferation of opportunistic infections. For more th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ae8cc04c24aea90936324832d8c8e2
https://pubmed.ncbi.nlm.nih.gov/35563225
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8
Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome
Autor: Sara Llames, E. Chacón-Solano, Jose Bonafont, Asunción Vicente, Marcela Del Rio, Victoria Galvez, Ángeles Mencía, Fernando Larcher, Marta Carretero, Wei-Li Di, Rodolfo Murillas
Publikováno v: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 280-290 (2020)
Current efforts to find specific genodermatoses treatments and define precise pathogenesis mechanisms require appropriate surrogate models with human cells. Although transgenic and gene knockout mouse models for several of these disorders exist, they
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006262ecb44587ad6941dcceb52e50a0
https://doi.org/10.1016/j.omtm.2020.05.031
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9
Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer‐prone genodermatoses
Autor: Marta Pevida, R. de Lucas, F. Díaz, Eulalia Baselga, Joaquín Dopazo, Carlos León, E. Chacón-Solano, M. Del Rio, Francisco García-García, Marta García, Sara Guerrero-Aspizua, Susana Puig, Sara Llames, José Carbonell-Caballero, Fernando Larcher, Ángeles Mencía, Claudio J. Conti, Lucía Martínez-Santamaría, J.A. Puig-Butillé, María José Escámez, R. Maseda
Publikováno v: British Journal of Dermatology
BRITISH JOURNAL OF DERMATOLOGY
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Chacón-Solano, E, León, C, Díaz, F, García-García, F, García, M, Escámez, M J, Guerrero-Aspizua, S, Conti, C J, Mencía, Á, Martínez-Santamaría, L, Llames, S, Pévida, M, Carbonell-Caballero, J, Puig-Butillé, J A, Maseda, R, Puig, S, de Lucas, R, Baselga, E, Larcher, F, Dopazo, J & Del Río, M 2019, ' Fibroblasts activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer-prone genodermatoses ', British journal of dermatology . https://doi.org/10.1111/bjd.17698
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
The British Journal of Dermatology
Summary Background Recessive dystrophic epidermolysis bullosa (RDEB), Kindler syndrome (KS) and xeroderma pigmentosum complementation group C (XPC) are three cancer‐prone genodermatoses whose causal genetic mutations cannot fully explain, on their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f6dfb9b88cfbfad017c17020b0becf
https://doi.org/10.1111/bjd.17698
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10
Human plasma gels: Their preparation and rheological characterization for cell culture applications in tissue engineering
Autor: Marta Pevida, Mario Díaz, Sara Llames, Alvaro Meana, Manuel Rendueles, Eva García-Pérez, Ismael Marcet, Lucía Barreda
Publikováno v: Journal of the Mechanical Behavior of Biomedical Materials. 89:107-113
Tissue engineering is one of the fields of clinical medicine that has forged ahead in recent years, especially because of its role as a potential alternative to organ transplantation. The main aim of this study has been the development of biocompatib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3988cb93fc28a154f35cbad30e64b8c1
https://doi.org/10.1016/j.jmbbm.2018.09.015
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