Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Sara, Eyal"'
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 6965-6975 (2024)
Externí odkaz:
https://doaj.org/article/bc41978bd5df41cfb2a13184282eba65
Autor:
Odelia Tepper-Shimshon, Nino Tetro, Roa’a Hamed, Natalia Erenburg, Emmanuelle Merquiol, Gourab Dey, Agam Haim, Tali Dee, Noa Duvdevani, Talin Kevorkian, Galia Blum, Eylon Yavin, Sara Eyal
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1211 (2024)
The space environment can affect the function of all physiological systems, including the properties of cell membranes. Our goal in this study was to explore the effect of simulated microgravity (SMG) on the cellular uptake of small molecules based o
Externí odkaz:
https://doaj.org/article/a437c92619c2452886187536e3081d90
Autor:
Mahmood Mahajna, Rami Abu Fanne, Mahmoud Odeh, Matitiahu Berkovitch, Elias Tannous, Sara Eyal, Shlomo Vinker, Ilan Green, Ilan Matok
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Tramadol is primarily metabolized by the highly polymorphic CYP2D6 enzyme, leading to a large spectrum of adverse events and clinical response. Ample evidence pointed a reduced CYPD26 activity score in individuals harboring the CYP2D6*10/
Externí odkaz:
https://doaj.org/article/c56970b747b94bb2a7a140022bc32584
Autor:
Avital Granit Mizrahi, Ahinoam Gugenheim, Haneen Hamad, Roa’a Hamed, Nino Tetro, Ofra Maimon, Salome Khutsurauli, Hovav Nechushtan, Benjamin Nisman, Deborah Duran, Widad Samman, Liron Birimberg-Schwartz, Myriam Grunewald, Sara Eyal, Tamar Peretz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
We recently demonstrated that the histone deacetylase inhibitor valproic acid (VPA) reprograms the cisplatin-induced metabolome of triple-negative breast cancer (TNBC) cells, including a shift in hexose levels. Accordingly, here, we tested the hypoth
Externí odkaz:
https://doaj.org/article/5c2f7c8cf790418bbeab010b21580f0d
Autor:
Avital Granit, Kumudesh Mishra, Dinorah Barasch, Tamar Peretz-Yablonsky, Sara Eyal, Or Kakhlon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cisplatin is an effective chemotherapeutic agent for treating triple negative breast cancer (TNBC). Nevertheless, cisplatin-resistance might develop during the course of treatment, allegedly by metabolic reprograming, which might influence epigenetic
Externí odkaz:
https://doaj.org/article/58963cd8425e4136b4a995fe953342f3
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/708561af42b84a8c9a5c70c8eb8656bc
Autor:
Angel Aledo-Serrano, Giulia Battaglia, Stephen Blenkinsop, Norman Delanty, Hasnaa M Elbendary, Sara Eyal, Alla Guekht, Medine I Gulcebi, David C Henshall, Michael S. Hildebrand, Bernadette Macrohon, Priyanka Madaan, Janet Mifsud, James D. Mills, Kathryn Hodgson Neill, Alessia Romagnolo, Annamaria Vezzani, Sanjay M Sisodiya
Publikováno v:
Seizure. 106:68-75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f25d71bebb8534c5bac55d36924cd6
https://doi.org/10.1016/j.seizure.2023.02.003
https://doi.org/10.1016/j.seizure.2023.02.003
Publikováno v:
Epilepsia. 64:311-319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba636cd41678cdafcb4287b7f5e0ea7b
https://doi.org/10.1111/epi.17479
https://doi.org/10.1111/epi.17479
Autor:
Emma Grabarnick (Portnoy), Alexander V. Andriyanov, Hadas Han, Sara Eyal, Yechezkel Barenholz
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2181 (2021)
Multidrug resistance (MDR) of cancer cells remains a major obstacle to favorable outcomes of treatment with many drugs, including doxorubicin. Most of the clinical trials failed to demonstrate the benefit of the drug efflux transporter P-glycoprotein
Externí odkaz:
https://doaj.org/article/eabeaa5a778f413688ce59b3a374319b
Publikováno v:
Epilepsia. 63:2949-2957
Lacosamide is increasingly being prescribed to pregnant women, although its effects on the developing fetus have not been fully clarified yet. Previously, we have shown that several antiseizure medications, particularly valproate, can affect the expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b89c44edba0de7989abc9713958bb9
https://doi.org/10.1111/epi.17395
https://doi.org/10.1111/epi.17395