Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sara, Ek"'
Autor:
Renée Daams, Thi Thu Phuong Tran, Mohamed Jemaà, Wondossen Sime, Ruta Mickeviciute, Sara Ek, Lars Rönnstrand, Julhash U. Kazi, Ramin Massoumi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-13 (2024)
Abstract The t(14;19)(q32;q13) is a rare recurring translocation found in B-cell lymphoproliferative malignancies, involving the Bcl-3 gene. This chromosomal translocation is often found in patients under the age of 50 and causes a more progressive d
Externí odkaz:
https://doaj.org/article/061a1aa27f0b4b8fa80ec99036ace4ae
Autor:
Claudia Mateiou, Lavanya Lokhande, Lan Hoa Diep, Mattis Knulst, Elias Carlsson, Sara Ek, Karin Sundfeldt, Anna Gerdtsson
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Immunotherapy has largely failed in ovarian carcinoma (OC), likely due to that the vast tumor heterogeneity and variation in immune response have hampered clinical trial outcomes. Tumor-immune microenvironment (TIME) profiling may aid in str
Externí odkaz:
https://doaj.org/article/3658ecb2591d44c98b7843782a179bb7
Publikováno v:
JMIR Research Protocols, Vol 13, p e55723 (2024)
BackgroundCutaneous T-cell lymphoma (CTCL) is a rare group of lymphomas that primarily affects the skin. Mycosis fungoides (MF) is the most common form of CTCL and Sézary syndrome (SS) is more infrequent. Early stages (IA-IIA) have a favorable progn
Externí odkaz:
https://doaj.org/article/880bd14d6928439fbb4b1f421387d944
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In Mantle Cell Lymphoma (MCL), the role of macrophages within the tumour microenvironment (TME) has recently gained attention due to their impact on prognosis and response to therapy. Despite their low absolute number in MCL tumour tissue, recent fin
Externí odkaz:
https://doaj.org/article/3a7278a0a0e7476d87eafe1a29abce44
Autor:
Anna Sandström Gerdtsson, Mattis Knulst, Johan Botling, Artur Mezheyeuski, Patrick Micke, Sara Ek
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe immune microenvironment of non-small cell lung cancer (NSCLC) is heterogeneous, which impedes the prediction of response to immune checkpoint inhibitors. We have mapped the expression of 49 proteins to spatial immune niches in 33 NSCLC tu
Externí odkaz:
https://doaj.org/article/741394138eef44ecae9ba7ccc63aed84
Autor:
Bieke Decaesteker, Amber Louwagie, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D’haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S. Roberts, Johannes Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark Zimmerman, Katleen De Preter, Frank Speleman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The development of neuroblastoma (NB) is regulated by multiple core transcription factors. Here, SOX11 is identified as a potential epigenetic master regulator upstream of the core regulatory circuitry in adrenergic high-risk neuroblastoma.
Externí odkaz:
https://doaj.org/article/c5e038d1e2b747e4b27f9e8e90add70c
Autor:
Karin Sundfeldt, Lavanya Lokhande, Anna S Gerdtsson, Sara Ek, Constantina Mateoiu, Asger M Frank, Elias Carlsson, Huaqiang Ouyang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/5dfbec4a607b4364a5754e27c2020ae4
Autor:
Joana Rodrigues, Lina Olsson, Daniel Nilsson, Lavanya Lokhande, May Hassan, Anna Porwit, Anna S Gerdtsson, Mats Jerkeman, Sara Ek
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/062c284851cf4dae849817b5577585e0
Autor:
Joana M. Rodrigues, Peter Hollander, Lina Schmidt, Eirinaios Gkika, Masoud Razmara, Darshan Kumar, Christian Geisler, Kirsten Grønbæk, Christian W. Eskelund, Riikka Räty, Arne Kolstad, Christer Sundström, Ingrid Glimelius, Anna Porwit, Mats Jerkeman, Sara Ek
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
The transcription factor MYC is a well-described oncogene with an important role in lymphomagenesis, but its significance for clinical outcome in mantle cell lymphoma (MCL) remains to be determined. We performed an investigation of the expression of
Externí odkaz:
https://doaj.org/article/39c05dfdcc6f46b984fdbc58d95a8e72
Autor:
Anna Sandström Gerdtsson, Joana de Matos Rodrigues, Christian Winther Eskelund, Simon Husby, Kirsten Grønbæk, Riikka Räty, Arne Kolstad, Christian Geisler, Anna Porwit, Mats Jerkeman, Sara Ek
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
The variable outcome to standard immunochemotherapy for mantle cell lymphoma (MCL) patients is a clinical challenge. Established risk factors, including high MCL International Prognostic Index (MIPI), high proliferation (Ki-67), non-classic (blastoid
Externí odkaz:
https://doaj.org/article/fd3814cc49814ec6ad284198f9418857