Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sara, Costi"'
Autor:
Jacek R Lindner, Ashkan Ebrahimi, Julian F Kochanowicz, Justyna Szczupak, Timothy Paris, Ahmed Abdelsamie, Sagar V Parikh, Rupert McShane, Sara Costi
Publikováno v:
JMIR Medical Education, Vol 9, p e46158 (2023)
BackgroundThe use of novel rapid-acting antidepressants for psychiatric disorders is expanding. The web-based Ketamine and Related Compounds International Journal Club (KIJC) was created during the COVID-19 pandemic by UK academic psychiatrists and t
Externí odkaz:
https://doaj.org/article/ada3d9d2c25045018329a374180a894e
Autor:
Flurin Cathomas, Laura Bevilacqua, Aarthi Ramakrishnan, Hope Kronman, Sara Costi, Molly Schneider, Kenny L. Chan, Long Li, Eric J. Nestler, Li Shen, Dennis S. Charney, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Ketamine has rapid and sustained antidepressant effects in patients with treatment-resistant depression (TRD). However, the underlying mechanisms of action are not well understood. There is increasing evidence that TRD is associated with a p
Externí odkaz:
https://doaj.org/article/9578aab04ada4803bcc382d8a0f3d527
Autor:
Sara Costi, Audrey Evers, Manish K. Jha, Matthew Klein, Jessica R. Overbey, Ki A. Goosens, JoColl Burgess, Kelvin Alvarez, Adriana Feder, Dennis S. Charney, James W. Murrough
Publikováno v:
Neurobiology of Stress, Vol 22, Iss , Pp 100505- (2023)
Background: Stress exposure is a key risk factor for the development of major depressive disorder and posttraumatic stress disorder. Enhancing stress resilience in at-risk populations could potentially protect against stress-induced disorders. The ad
Externí odkaz:
https://doaj.org/article/2793ed9c99cb4a19aeb654f275053d32
Autor:
Sara Costi, Laurel S. Morris, Abigail Collins, Nicolas F. Fernandez, Manishkumar Patel, Hui Xie, Seunghee Kim-Schulze, Emily R. Stern, Katherine A. Collins, Flurin Cathomas, Michael K. Parides, Alexis E. Whitton, Diego A. Pizzagalli, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Increased levels of peripheral cytokines have been previously associated with depression in preclinical and clinical research. Although the precise nature of peripheral immune dysfunction in depression remains unclear, evidence from animal s
Externí odkaz:
https://doaj.org/article/ba742c5afe7d476aa19d67c3d88c7bb5
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Stress exposure is one of the greatest risk factors for psychiatric illnesses, including major depressive disorder (MDD) and posttraumatic stress disorder (PTSD). Enhancing stress resilience could potentially protect against the development of stress
Externí odkaz:
https://doaj.org/article/4adadd6440e24654bd752e50f38128bc
Autor:
Sarah Boukezzi, Sara Costi, Lisa M. Shin, Seunghee Kim-Schulze, Flurin Cathomas, Abigail Collins, Scott J. Russo, Laurel S. Morris, James W. Murrough
Publikováno v:
Brain, Behavior, and Immunity. 104:205-212
Depression is characterized by altered neurobiological responses to threat and inflammation may be involved in the development and maintenance of symptoms. However, the mechanistic pathways underlying the relationship between the neural underpinnings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3b16a0992aed304763b384c6584869
https://doi.org/10.1016/j.bbi.2022.05.015
https://doi.org/10.1016/j.bbi.2022.05.015
Autor:
Amit Anand, Sanjay J. Mathew, Gerard Sanacora, James W. Murrough, Fernando S. Goes, Murat Altinay, Amy S. Aloysi, Ali A. Asghar-Ali, Brian S. Barnett, Lee C. Chang, Katherine A. Collins, Sara Costi, Sidra Iqbal, Manish K. Jha, Kamini Krishnan, Donald A. Malone, Sina Nikayin, Steven E. Nissen, Robert B. Ostroff, Irving M. Reti, Samuel T. Wilkinson, Kathy Wolski, Bo Hu
Publikováno v:
New England Journal of Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1004300a18618ff4d944d59b16804fb1
https://doi.org/10.1056/nejmoa2302399
https://doi.org/10.1056/nejmoa2302399
Publikováno v:
CNS Drugs. 36:207-216
Major depressive disorder (MDD) is a leading cause of disability worldwide and less than one-third of patients with MDD achieve stable remission of symptoms, despite currently available treatments. Although MDD represents a serious health problem, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f187cdac2b3f2c8cada37d5ad2ce4cc
https://doi.org/10.1007/s40263-021-00885-y
https://doi.org/10.1007/s40263-021-00885-y
Autor:
Jacek Lindner, Ashkan Ebrahimi, Julian Kochanowicz, Justyna Szczupak, Timothy Paris, Sagar Parikh, Rupert McShane, Sara Costi
BACKGROUND Improving clinical outcomes in mental health disorders involves both identifying and disseminating new treatments. Interest in the uptake of novel rapid acting antidepressants, like ketamine and related compounds, for psychiatric disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef551510da26aae6be49f75e005db4ff
https://doi.org/10.2196/preprints.46158
https://doi.org/10.2196/preprints.46158
Autor:
Scott Russo, Flurin Cathomas, Hsiao-yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murrough
Psychosocial stress has profound effects on the body, including the peripheral immune system and the brain1,2. Although a large number of pre-clinical and clinical studies have linked peripheral immune system alterations to stress-related disorders s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c4c5f4f941779901d8849faeb60f52
https://doi.org/10.21203/rs.3.rs-1647827/v1
https://doi.org/10.21203/rs.3.rs-1647827/v1