Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sara, Caratelli"'
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Ingrid Cifola, Sara Caratelli, Giuseppe Sconocchia, Igea D’Agnano, Carlo Cenciarelli
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas a
Externí odkaz:
https://doaj.org/article/e4a8f209c4104b86b08c0037bf0c96a9
Autor:
Giuseppe Sconocchia, Giulia Lanzilli, Valeriana Cesarini, Domenico A Silvestris, Katayoun Rezvani, Roberto Arriga, Sara Caratelli, Ken Chen, Jinzhuang Dou, Carlo Cenciarelli, Gabriele Toietta, Silvia Baldari, Tommaso Sconocchia, Francesca De Paolis, Anna Aureli, Giandomenica Iezzi, Maria Irno Consalvo, Francesco Buccisano, Maria I del Principe, Luca Maurillo, Adriano Venditti, Alessio Ottaviani, Giulio C Spagnoli
The FcγRII (CD32) ligands are IgFc fragments and pentraxins. The existence of additional ligands is unknown. We engineered T cells with human chimeric receptors resulting from the fusion between CD32 extracellular portion and transmembrane CD8α lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d94e7643368932ed25648cf607c3be
https://hdl.handle.net/2108/307175
https://hdl.handle.net/2108/307175
Autor:
Giuseppe Sconocchia, Sara Caratelli, Tommaso Sconocchia, Roberto Arriga, Andrea Coppola, Giulia Lanzilli, Davide Lauro, Adriano Venditti, Maria Ilaria Del Principe, Francesco Buccisano, Luca Maurillo, Soldano Ferrone
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
For many years, disappointing results have been generated by many investigations, which have utilized a variety of immunologic strategies to enhance the ability of a patient’s immune system to recognize and eliminate malignant cells. However, in re
Externí odkaz:
https://doaj.org/article/1d258a6762934cae8ffb083a304d583f
Autor:
Giuseppe Sconocchia, Serenella Eppenberger-Castori, Inti Zlobec, Eva Karamitopoulou, Roberto Arriga, Andrea Coppola, Sara Caratelli, Giulio Cesare Spagnoli, Davide Lauro, Alessandro Lugli, Junyi Han#, Giandomenica Iezzi, Cristina Ferrone, Amedeo Ferlosio, Luigi Tornillo, Raoul Droeser, Piero Rossi, Antonio Attanasio, Soldano Ferrone, Luigi Terracciano
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 1, Pp 31-42 (2014)
The goal of this study was to determine the frequency of HLA class II antigen expression in colorectal carcinoma (CRC) tumors, its association with the clinical course of the disease, and the underlying mechanism(s). Two tissue microarrays constructe
Externí odkaz:
https://doaj.org/article/b1b1b96da2874fa2a0833dfda078018f
Autor:
Valentina Tassinari, Piergiorgio La Rosa, Eugenia Guida, Ambra Colopi, Sara Caratelli, Francesca De Paolis, Angela Gallo, Carlo Cenciarelli, Giuseppe Sconocchia, Susanna Dolci, Valeriana Cesarini
Publikováno v:
Mechanisms of Ageing and Development. 212:111807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::955695ef216eabd6cdfc8146c88512a8
https://doi.org/10.1016/j.mad.2023.111807
https://doi.org/10.1016/j.mad.2023.111807
Autor:
Giuseppe Sconocchia, Giulia Lanzilli, Valeriana Cesarini, Domenico Alessandro Silvestris, Roberto Arriga, Katayoun Rezvani, Sara Caratelli, Ken Chen, Jinzhuang Dou, Carlo Cenciarelli, Gabriele Toietta, Silvia Baldari, Tommaso Sconocchia, Francesca De Paolis, Anna Aureli, Giandomenica Iezzi, Maria Ilaria del Principe, Adriano Venditti, Alessio Ottaviani, Giulio Cesare Spagnoli
Fcγ RIIA (CD32A) and their ligands, including the immunoglobulin Fc fragment and pentraxins, are key players in a variety of innate immune responses. Still unclear is whether additional ligands of CD32A do exist. The objective of this study is to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c23d5afee5c8403df473be3871f31a
https://doi.org/10.1101/2021.12.22.473841
https://doi.org/10.1101/2021.12.22.473841
Autor:
Giuseppe Sconocchia, Davide Lauro, Roberto Arriga, Soldano Ferrone, Sara Caratelli, Giandomenica Iezzi, Mario Roselli, Tommaso Sconocchia, Alessio Ottaviani, Gianpietro Dotti, Giulio C. Spagnoli, Andrea Coppola, Giulia Lanzilli, Carlo Cenciarelli
Publikováno v:
Int J Cancer
International journal of cancer (Online) (2019). doi:10.1002/ijc.32618
info:cnr-pdr/source/autori:1 Arriga, Roberto; 2 Caratelli, Sara; 2 Lanzilli, Giulia; 2 Ottaviani, Alessio; 2 Cenciarelli, Carlo; 3 Sconocchia, Tommaso; 2 Spagnoli, Giulio C.; 4 Iezzi, Giandomenica; 1 Roselli, Mario; 1 Lauro, Davide; 1 Coppola, Andrea; 5 Dotti, Gianpietro; 6 Ferrone, Soldano; 2 Sconocchia, Giuseppe/titolo:CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab/doi:10.1002%2Fijc.32618/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
International journal of cancer (Online) (2019). doi:10.1002/ijc.32618
info:cnr-pdr/source/autori:1 Arriga, Roberto; 2 Caratelli, Sara; 2 Lanzilli, Giulia; 2 Ottaviani, Alessio; 2 Cenciarelli, Carlo; 3 Sconocchia, Tommaso; 2 Spagnoli, Giulio C.; 4 Iezzi, Giandomenica; 1 Roselli, Mario; 1 Lauro, Davide; 1 Coppola, Andrea; 5 Dotti, Gianpietro; 6 Ferrone, Soldano; 2 Sconocchia, Giuseppe/titolo:CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab/doi:10.1002%2Fijc.32618/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
KRAS mutations hinder therapeutic efficacy of epidermal growth factor receptor (EGFR)-specific monoclonal antibodies cetuximab and panitumumab-based immunotherapy of EGFR+ cancers. Although cetuximab inhibits KRAS-mutated cancer cell growth in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc87c65724ea6b261df04062aa3098c3
Autor:
Carlo Cenciarelli, Giuseppe Sconocchia, Giulia Lanzilli, Thomas Caceci, Roberto Arriga, Hany E. Marei, Asma Althani, Alessio Ottaviani, Mario Roselli, Tommaso Sconocchia, Sara Caratelli
Publikováno v:
Biochemical pharmacology 166 (2019): 335–346. doi:10.1016/j.bcp.2019.06.002
info:cnr-pdr/source/autori:Hany E. Marei 1, Asma Althani 2, Thomas Caceci 3, Roberto Arriga 4, Tommaso Sconocchia 5, Alessio Ottaviani 6, Giulia Lanzilli 6, Mario Roselli 4, Sara Caratelli 6, Carlo Cenciarelli 6*, Giuseppe Sconocchia 6*/titolo:Recent perspective on CAR and Fcgamma-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes/doi:10.1016%2Fj.bcp.2019.06.002/rivista:Biochemical pharmacology/anno:2019/pagina_da:335/pagina_a:346/intervallo_pagine:335–346/volume:166
info:cnr-pdr/source/autori:Hany E. Marei 1, Asma Althani 2, Thomas Caceci 3, Roberto Arriga 4, Tommaso Sconocchia 5, Alessio Ottaviani 6, Giulia Lanzilli 6, Mario Roselli 4, Sara Caratelli 6, Carlo Cenciarelli 6*, Giuseppe Sconocchia 6*/titolo:Recent perspective on CAR and Fcgamma-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes/doi:10.1016%2Fj.bcp.2019.06.002/rivista:Biochemical pharmacology/anno:2019/pagina_da:335/pagina_a:346/intervallo_pagine:335–346/volume:166
The chimeric antigen receptor T cell (CAR-T cell) immunotherapy currently represents a hot research trend and it is expected to revolutionize the field of cancer therapy. Promising outcomes have been achieved using CAR-T cell therapy for haematologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d039f4d49e6169c4859867b4839f91a1
https://pubmed.ncbi.nlm.nih.gov/31176617
https://pubmed.ncbi.nlm.nih.gov/31176617
Autor:
Giuseppe Sconocchia, Soldano Ferrone, Giulia Lanzilli, Alessio Ottaviani, Mario Roselli, Giulio C. Spagnoli, Carlo Cenciarelli, Gianpietro Dotti, Giandomenica Iezzi, Roberto Arriga, Tommaso Sconocchia, Sara Caratelli, Davide Lauro
KRAS mutation hinders the therapeutic efficacy of epidermal-growth-factor-receptor (EGFR) mAb (cetuximab and panitumumab)-based immunotherapy of EGFR+ cancers. Although, cetuximab controls KRAS-mutated cancer cell growthin vitroutilizing a NK cell-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84e9498302713b893e06199c15f5734
Autor:
Soldano Ferrone, Roberto Arriga, Donatella Pastore, Giuseppe Sconocchia, Davide Lauro, Maria Ilaria Del Principe, Giulia Lanzilli, Gianpietro Dotti, Alessio Ottaviani, Tommaso Sconocchia, Carlo Cenciarelli, Hongwei Du, Adriano Venditti, Elisa Landoni, Sara Caratelli, Barbara Savoldo
Publikováno v:
Int J Cancer
International journal of cancer (Online) (2019). doi:10.1002/ijc.32663
info:cnr-pdr/source/autori:Caratelli S1, Arriga R2, Sconocchia T3, Ottaviani A1, Lanzilli G1, Pastore D2, Cenciarelli C1, Venditti A4, Del Principe MI4, Lauro D2, Landoni E5, Du H5, Savoldo B5, Ferrone S6, Dotti G5, Sconocchia G1./titolo:In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab/doi:10.1002%2Fijc.32663/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
International journal of cancer (Online) (2019). doi:10.1002/ijc.32663
info:cnr-pdr/source/autori:Caratelli S1, Arriga R2, Sconocchia T3, Ottaviani A1, Lanzilli G1, Pastore D2, Cenciarelli C1, Venditti A4, Del Principe MI4, Lauro D2, Landoni E5, Du H5, Savoldo B5, Ferrone S6, Dotti G5, Sconocchia G1./titolo:In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab/doi:10.1002%2Fijc.32663/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Cetuximab and panitumumab bind the human epidermal growth factor receptor (EGFR). Although the chimeric cetuximab (IgG1) triggers antibody-dependent-cellular-cytotoxicity (ADCC) of EGFR positive target cells, panitumumab (a human IgG2) does not. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f869bac4c77ba93c3b44ad481eeeb743
https://pubmed.ncbi.nlm.nih.gov/31479522
https://pubmed.ncbi.nlm.nih.gov/31479522