Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Sara, Bravaccini"'
Autor:
Alessandra Virga, Caterina Gianni, Michela Palleschi, Davide Angeli, Filippo Merloni, Roberta Maltoni, Paola Ulivi, Giovanni Martinelli, Ugo De Giorgi, Sara Bravaccini
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2183 (2024)
Background: Patients with hormone receptor-positive (HR+)/HER2- metastatic breast cancer (mBC) generally receive hormonal therapy (HT) combined with CDK4/6 inhibitors (CDK4/6i). Despite this treatment, resistance mechanisms to CDK4/6i emerge and the
Externí odkaz:
https://doaj.org/article/b4f6e5029c6b49319727b60fcd9c8bfa
Autor:
Roberta Maltoni, Andrea Roncadori, William Balzi, Massimiliano Mazza, Fabio Nicolini, Michela Palleschi, Paola Ulivi, Sara Bravaccini
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 498 (2024)
Background: Cyclin-dependent kinase 4 and 6 (CDK4 and CDK6) inhibitors have changed the therapeutic management of hormone receptor-positive (HR+) metastatic breast cancer (mBC) by targeting the cell cycle machinery and overcoming endocrine resistance
Externí odkaz:
https://doaj.org/article/25d2bd4c7187465ba0c974d9e4b44c1d
Autor:
Giacomo Miserocchi, Martine Bocchini, Michela Cortesi, Chiara Arienti, Alessandro De Vita, Chiara Liverani, Laura Mercatali, Sara Bravaccini, Paola Ulivi, Michele Zanoni
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumors are complex and heterogeneous diseases characterized by an intricate milieu and dynamically in connection with surrounding and distant tissues. In the last decades, great efforts have been made to develop novel preclinical models able to recap
Externí odkaz:
https://doaj.org/article/542c254467e344c8a7a6a08ef6c58f1f
Autor:
Roberta Maltoni, William Balzi, Tania Rossi, Francesco Fabbri, Sara Bravaccini, Maria Teresa Montella, Ilaria Massa, Lucia Bertoni, Fabio Falcini, Mattia Altini
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 433-438 (2022)
The risk of relapse for early breast cancer (BC) patients persists even after decades and to date, no specific and sensitive effective circulating biomarker for recurrence prediction has been identified yet. The international guidelines do not recomm
Externí odkaz:
https://doaj.org/article/bfdd26a08f7c46bbbf80dabff4687db6
Autor:
Francesca Pirini, Michela Cortesi, Maria Maddalena Tumedei, Michele Zanoni, Sara Ravaioli, Sara Bravaccini
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
The role of the intestinal microbiota in the promotion, progression, and response to therapies is gaining importance, but recent studies confirm the presence of microbiota also in the tumor, thus becoming a component of the tumor microenvironment. Th
Externí odkaz:
https://doaj.org/article/10c53cf28db24a9fa541ac26dc8f12bc
Autor:
Sara Bravaccini, Fabio Nicolini, Michele Zanoni, Anna Gaimari, Claudio Cerchione, Roberta Maltoni, Francesca Pirini, Lucia Mazzotti, Michela Cortesi, Sara Ravaioli, Maria Maddalena Tumedei, Massimiliano Mazza
Publikováno v:
Translational Oncology, Vol 26, Iss , Pp 101541- (2022)
Zhang et al. reported the impact of different risk factors and comorbidities in COVID-19 lethality. The authors observed that the odds of dying by COVID-19 in cancer patients decrease with age and cancer becomes a non-significant factor above 80 year
Externí odkaz:
https://doaj.org/article/5f27b11055b943d494e3bc8c52f95648
Autor:
Maria Maddalena Tumedei, Filippo Piccinini, Irene Azzali, Francesca Pirini, Sara Bravaccini, Serena De Matteis, Claudio Agostinelli, Gastone Castellani, Michele Zanoni, Michela Cortesi, Barbara Vergani, Biagio Eugenio Leone, Simona Righi, Anna Gazzola, Beatrice Casadei, Davide Gentilini, Luciano Calzari, Francesco Limarzi, Elena Sabattini, Andrea Pession, Marcella Tazzari, Clara Bertuzzi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9909 (2023)
The majority of patients with Follicular Lymphoma (FL) experience subsequent phases of remission and relapse, making the disease “virtually” incurable. To predict the outcome of FL patients at diagnosis, various clinical-based prognostic scores h
Externí odkaz:
https://doaj.org/article/ef89bf2c43a241479541142460aa2176
Autor:
Sara Ravaioli, Roberta Maltoni, Barbara Pasculli, Paola Parrella, Anna Maria Giudetti, Daniele Vergara, Maria Maddalena Tumedei, Francesca Pirini, Sara Bravaccini
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Androgen receptor (AR) is expressed in 60-70% of breast cancers (BCs) and the availability of anti-AR compounds, currently used for treating prostate cancer, paves the way to tackle specifically AR-positive BC patients. The prognostic and predictive
Externí odkaz:
https://doaj.org/article/b67955f818b24cc7a58287a220eb2ff7
Autor:
Chengzhi Zhou, Yilin Yang, Xinqing Lin, Nianxin Fang, Likun Chen, Juhong Jiang, Haiyi Deng, Yu Deng, Minghui Wan, Guihuan Qiu, Ni Sun, Di Wu, Xiang Long, Changhao Zhong, Xiaohong Xie, Zhanhong Xie, Ming Liu, Ming Ouyang, Yinyin Qin, Francesco Petrella, Alfonso Fiorelli, Sara Bravaccini, Yuki Kataoka, Satoshi Watanabe, Taichiro Goto, Piergiorgio Solli, Hitoshi Igai, Yuichi Saito, Nikolaos Tsoukalas, Takeo Nakada, Shiyue Li, Rongchang Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundCheckpoint inhibitor–related pneumonitis (CIP) is a lethal immune-related adverse event. However, the development process of CIP, which may provide insight into more effective management, has not been extensively examined.MethodsWe conduc
Externí odkaz:
https://doaj.org/article/55d8fcbc06d446b1bcfde80d09759586
Autor:
Maria Maddalena Tumedei, Sara Ravaioli, Federica Matteucci, Monica Celli, Ugo De Giorgi, Roberta Gunelli, Maurizio Puccetti, Giovanni Paganelli, Sara Bravaccini
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Bladder cancer (BCa) patients are diagnosed by cytology and cystoscopy. However, these diagnostic tests bear some limitations. We sought for reliable biomarkers to better determine BCa extension. Prostate-specific membrane antigen (PSMA) app
Externí odkaz:
https://doaj.org/article/9e48e4bb4424421c8efc0070bd91a8d6