Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sara, Biagiotti"'
Autor:
Sara Biagiotti, Barbara Canonico, Mattia Tiboni, Faiza Abbas, Elena Perla, Mariele Montanari, Michela Battistelli, Stefano Papa, Luca Casettari, Luigia Rossi, Michele Guescini, Mauro Magnani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Extracellular vesicles (EVs) are promising natural nanocarriers for the delivery of therapeutic agents. As with any other kind of cell, red blood cells (RBCs) produce a limited number of EVs under physiological and pathological conditions. T
Externí odkaz:
https://doaj.org/article/bb826e0143ea47b5a5eb27d8dc5b53fe
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a07e9559db6a4bb691f769175ea70302
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
This review focuses on the role of human red blood cells (RBCs) as drug carriers. First, a general introduction about RBC physiology is provided, followed by the presentation of several cases in which RBCs act as natural carriers of drugs. This is du
Externí odkaz:
https://doaj.org/article/50b1217d45ab446a9d7691927f0fc81e
Autor:
Alessandro Bregalda, Claudia Carducci, Maria Teresa Viscomi, Francesca Pierigè, Sara Biagiotti, Michele Menotta, Federica Biancucci, Tiziana Pascucci, Vincenzo Leuzzi, Mauro Magnani, Luigia Rossi
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106093- (2023)
Untreated phenylketonuria (PKU) patients and PKU animal models show hypomyelination in the central nervous system and white matter damages, which are accompanied by myelin basic protein (MBP) impairment. Despite many assumptions, the primary explanat
Externí odkaz:
https://doaj.org/article/ea2f98d722914820afd10ddc5e353fa0
Autor:
Sara Biagiotti, Faiza Abbas, Mariele Montanari, Chiara Barattini, Luigia Rossi, Mauro Magnani, Stefano Papa, Barbara Canonico
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 365 (2023)
The article is divided into several sections, focusing on extracellular vesicles’ (EVs) nature, features, commonly employed methodologies and strategies for their isolation/preparation, and their characterization/visualization. This work aims to gi
Externí odkaz:
https://doaj.org/article/378029e8d7694bedb53493216d73e34e
Autor:
Sara Biagiotti, Ambra Barone, Mattia Paolo Aliano, Giulia Federici, Marco Malatesta, Caterina Caputi, Silvia Soddu, Vincenzo Leuzzi, Luciana Chessa, Mauro Magnani
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Most of the ATM variants associated with Ataxia Telangiectasia are still classified as variants with uncertain significance. Ataxia Telangiectasia is a multisystemic disorder characterized by “typical” and “atypical” phenotypes, with early-on
Externí odkaz:
https://doaj.org/article/b15e92c56b87431ca9e113d9d536b17a
Autor:
Irene Bagaloni, Axel Visani, Sara Biagiotti, Annamaria Ruzzo, Mohsen Navari, Maryam Etebari, Lucia Mundo, Massimo Granai, Stefano Lazzi, Alessandro Isidori, Federica Loscocco, Jiejin Li, Lorenzo Leoncini, Giuseppe Visani, Mauro Magnani, Pier Paolo Piccaluga
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Altered cellular energetic metabolism has recently emerged as important feature of neoplastic cells. Indeed, interfering with cancer cell metabolism might represent a suitable therapeutic strategy. In this study, we aimed to assess glucose metabolism
Externí odkaz:
https://doaj.org/article/305e9d07524b48dba08c61891a543639
Autor:
Michele Menotta, Sara Biagiotti, Chiara Spapperi, Sara Orazi, Luigia Rossi, Luciana Chessa, Vincenzo Leuzzi, Daniela D’Agnano, Annarosa Soresina, Roberto Micheli, Mauro Magnani
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-7 (2017)
Abstract Background Ataxia Telangiectasia (AT) is a rare incurable genetic disease, caused by biallelic mutations in the Ataxia Telangiectasia-Mutated (ATM) gene. Treatment with glucocorticoid analogues has been shown to improve the neurological symp
Externí odkaz:
https://doaj.org/article/e8db8bd3c8c94f99bffffefa4e97cd51
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216668 (2019)
Oxidative stress has been shown to play a crucial role in the pathophysiology of the neurodegenerative disease Ataxia Telangiectasia. We have recently demonstrated that Dexamethasone treatment is able to counteract the oxidative state by promoting nu
Externí odkaz:
https://doaj.org/article/fa0b08b0369d4b678fc9620590b45b53
Autor:
Stefano Francini, Alberto Scotti Del Greco, Michele Marconcini, Daniele Di Benedetto, Tomasz Jurek, Sara Biagiotti, Vittorio Michelassi
Publikováno v:
Journal of Turbomachinery. 144
This paper describes a coupled experimental and computational fluid dynamics (CFD) campaign conducted on a 1.5 intermediate turbine stage in the full range of operating conditions, from start-up to design point under variable expansion ratio and phys