Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Saqib Kidwai"'
Autor:
Tannu Priya Gosain, Saurabh Chugh, Zaigham Abbas Rizvi, Neeraj Kumar Chauhan, Saqib Kidwai, Krishan Gopal Thakur, Amit Awasthi, Ramandeep Singh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The genome of Mycobacterium tuberculosis encodes for a large repertoire of toxin-antitoxin systems. In the present study, MenT3 and MenT4 toxins belonging to MenAT subfamily of TA systems have been functionally characterized. We demonstrate
Externí odkaz:
https://doaj.org/article/1cfe23946fcc4272ad091ea4e17742c3
Autor:
Deepika Chaudhary, Avantika Singh, Mardiana Marzuki, Abhirupa Ghosh, Saqib Kidwai, Tannu Priya Gosain, Kiran Chawla, Sonu Kumar Gupta, Nisheeth Agarwal, Sudipto Saha, Yashwant Kumar, Krishan Gopal Thakur, Amit Singhal, Ramandeep Singh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract There is an urgent need to validate new drug targets and identify small molecules that possess activity against both drug-resistant and drug-sensitive bacteria. The enzymes belonging to amino acid biosynthesis have been shown to be essential
Externí odkaz:
https://doaj.org/article/e0e05820dad245dc96c503e9bde585fa
Autor:
Amritansh Bhanot, Ajitesh Lunge, Naresh Kumar, Saqib Kidwai, Ramandeep Singh, Sandeep Sundriyal, Nisheeth Agarwal
Publikováno v:
Results in Chemistry, Vol 5, Iss , Pp 100904- (2023)
The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) in humans, is a primary reason for treatment failure. Currently, only limited options are available for the management of multi-drug
Externí odkaz:
https://doaj.org/article/20092200e685447cb071d22f95a302ff
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/0bcb6640bbc5471dbd6c3ae6b31a16b5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/711a56ebff03475fbde6c0ebf0c18363
Autor:
Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, Ravi P. Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S. Rawat, Ramandeep Singh
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compati
Externí odkaz:
https://doaj.org/article/bd7c19cd90944030be789debdd42df2c
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Bacterial citrate lyase activity has been demonstrated in various eukaryotes, bacteria and archaea, underscoring their importance in energy metabolism of the cell. While the bacterial citrate lyase comprises of three different subunits, M. tuberculos
Externí odkaz:
https://doaj.org/article/414cf3eddce64e059de0fa7b1c241ad5
Publikováno v:
Journal of Porphyrins and Phthalocyanines.
Autor:
Kondreddy Shivaprasad, Saqib Kidwai, Sumanth Gopavaram, Surbhi Mahender Saini, Krishna Reddy, Saurabh Chugh, Ramandeep Singh, Sandeep Chandrashekharappa
Publikováno v:
Journal of Molecular Structure. 1284:135439
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 36
A series of 2,5-disubstituted benzimidazole derivatives was synthesized with the aim to identify compounds with potent anti-TB activity. All the compounds were screened in vitro against cultured Mycobacterium tuberculosis H