Zobrazeno 1 - 10
of 903
pro vyhledávání: '"Saponaro P"'
Autor:
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mammalian DNA replication relies on various DNA helicase and nuclease activities to ensure accurate genetic duplication, but how different helicase and nuclease activities are properly directed remains unclear. Here, we identify the ubiquiti
Externí odkaz:
https://doaj.org/article/28ce5cbc0af0403c82bcaf2f474d55ce
Autor:
Maria Colomba Comes, Livia Fucci, Sabino Strippoli, Samantha Bove, Gerardo Cazzato, Carmen Colangiuli, Ivana De Risi, Ileana De Roma, Annarita Fanizzi, Fabio Mele, Maurizio Ressa, Concetta Saponaro, Clara Soranno, Rosita Tinelli, Michele Guida, Alfredo Zito, Raffaella Massafra
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Risk stratification and treatment benefit prediction models are urgent to improve negative sentinel lymph node (SLN-) melanoma patient selection, thus avoiding costly and toxic treatments in patients at low risk of recurrence. To
Externí odkaz:
https://doaj.org/article/95ad4c7525344afab6eec62c16a1a0f7
Autor:
Annarita Fanizzi, Maria Colomba Comes, Samantha Bove, Elisa Cavalera, Paola de Franco, Alessia Di Rito, Angelo Errico, Marco Lioce, Francesca Pati, Maurizio Portaluri, Concetta Saponaro, Giovanni Scognamillo, Ippolito Troiano, Michele Troiano, Francesco Alfredo Zito, Raffaella Massafra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Several studies have emphasised how positive and negative human papillomavirus (HPV+ and HPV−, respectively) oropharyngeal squamous cell carcinoma (OPSCC) has distinct molecular profiles, tumor characteristics, and disease outcomes. Differ
Externí odkaz:
https://doaj.org/article/3a58af39bb7947f98b520802b8a424b4
Autor:
Patricia Rojas, Jianming Wang, Giovanni Guglielmi, Martina Mustè Sadurnì, Lucas Pavlou, Geoffrey Ho Duen Leung, Vijay Rajagopal, Fabian Spill, Marco Saponaro
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background DNA replication progression can be affected by the presence of physical barriers like the RNA polymerases, leading to replication stress and DNA damage. Nonetheless, we do not know how transcription influences overall DNA replicat
Externí odkaz:
https://doaj.org/article/072a3bf961d1417a9d243d2700149b95
Autor:
Alessandro Porro, Andrea Saponaro, Roberta Castelli, Bianca Introini, Anahita Hafez Alkotob, Golnaz Ranjbari, Uta Enke, Jana Kusch, Klaus Benndorf, Bina Santoro, Dario DiFrancesco, Gerhard Thiel, Anna Moroni
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Binding of cAMP to Hyperpolarization activated cyclic nucleotide gated (HCN) channels facilitates pore opening. It is unclear why the isolated cyclic nucleotide binding domain (CNBD) displays in vitro lower affinity for cAMP than the full-le
Externí odkaz:
https://doaj.org/article/54ee296cfd5a4b9b8c10a343ba531e63
Autor:
Sara Saponaro, Francesca Lizzi, Giacomo Serra, Francesca Mainas, Piernicola Oliva, Alessia Giuliano, Sara Calderoni, Alessandra Retico
Publikováno v:
Brain Informatics, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Background: The integration of the information encoded in multiparametric MRI images can enhance the performance of machine-learning classifiers. In this study, we investigate whether the combination of structural and functional MRI might im
Externí odkaz:
https://doaj.org/article/95e49b4b3f694885875c848e78650032
Autor:
Luisa Galati, Purnima Gupta, Antonio Tufaro, Mariarosaria Marinaro, Concetta Saponaro, David Israel Escobar Marcillo, Donato Loisi, Rajdip Sen, Alexis Robitaille, Rosario N. Brancaccio, Cyrille Cuenin, Sandrine McKay-Chopin, Angelo Virgilio Paradiso, Václav Liška, Pavel Souček, Francesco Alfredo Zito, David J. Hughes, Massimo Tommasino, Tarik Gheit
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-7 (2023)
Abstract Background Although the role of viral agents, such as human papillomavirus (e.g. HPV16, HPV18) in colorectal cancer (CRC) has been previously investigated, results remain inconclusive. Methods To further evaluate the involvement of oncogenic
Externí odkaz:
https://doaj.org/article/6b68842a603b48a9ac7b98a65fce0ab6
Autor:
Michele Sanza, Matteo Monzio Compagnoni, Giulia Caggiu, Liliana Allevi, Angelo Barbato, Jeannette Campa, Flavia Carle, Barbara D’avanzo, Teresa Di Fiandra, Lucia Ferrara, Andrea Gaddini, Alessio Saponaro, Salvatore Scondotto, Valeria D Tozzi, Stefano Lorusso, Cristina Giordani, Giovanni Corrao, Antonio Lora
Publikováno v:
International Journal of Mental Health Systems, Vol 17, Iss 1, Pp 1-13 (2023)
Abstract Background Italy can be viewed as a laboratory to assess the quality of mental healthcare delivered in a community-oriented system, especially for severe mental disorders, such as personality disorders. Although initiatives based on clinical
Externí odkaz:
https://doaj.org/article/d56b034accb046b9839d81785146415b
Autor:
Valeria D. Tozzi, Helen Banks, Lucia Ferrara, Angelo Barbato, Giovanni Corrao, Barbara D’avanzo, Teresa Di Fiandra, Andrea Gaddini, Matteo Monzio Compagnoni, Michele Sanza, Alessio Saponaro, Salvatore Scondotto, Antonio Lora
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Mental health (MH) care often exhibits uneven quality and poor coordination of physical and MH needs, especially for patients with severe mental disorders. This study tests a Population Health Management (PHM) approach to identify
Externí odkaz:
https://doaj.org/article/7e9d7960635a4e15be0ef414fe2f12c0
Autor:
Vittorio Saponaro, Clémence Mey, Irène Vonfeld, Antoine Chamagne, Maria‐Paz Alvarado, Jean‐luc Cadoré, Valérie Chetboul, Loïc Desquilbet
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 5, Pp 1679-1684 (2023)
Abstract Background Third heart sounds in cats frequently are associated with hypertrophic cardiomyopathy (HCM) but their exact characterization and timing within the cardiac cycle remains unknown. Objectives Characterize third heart sounds in cats b
Externí odkaz:
https://doaj.org/article/78d0a16c1d0744f0b303f4031a2225b9