Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sapna Vijayakumar"'
Autor:
Kelly Blinzler, Martine C. Maculaitis, Sapna Vijayakumar, Jingyan Yang, Joshua Lankin, Ahmed Shelbaya
Publikováno v:
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 36(1)
The adoption of oncology biosimilars has been slow in the USA, which may be attributed in part to stakeholder perceptions and lack of operational guidance that supports favorable access to biosimilars. Our objective was to understand the real-world i
Autor:
Robert A. Chong, Horacio Nastri, Guizhong Liu, Gadi Gazit Bornstein, Sapna Vijayakumar, Zhen-Qiang Pan, Huei-Chi Wen, Stuart A. Aaronson, Yaa Abu
Publikováno v:
Genes & Cancer
The LOW-density lipoprotein related protein 6 (LRP6) receptor is an important effector of canonical Wnt signaling, a developmental pathway, whose dysregulation has been implicated in various diseases including cancer. The membrane proximal low-densit
Autor:
Yan Chen, Luca Grumolato, Stuart A. Aaronson, Guizhong Liu, Gal Akiri, Shen Yao, Sapna Vijayakumar, Ioana A. Rus
Publikováno v:
Cancer Cell. 19(5):601-612
SummaryWnt canonical signaling is critical for normal development as well as homeostasis of several epithelial tissues, and constitutive activation of this pathway is commonly observed in carcinomas. We show here that 50% of human sarcomas (n = 45) a
Publikováno v:
Oncogene
Human gastric carcinomas are among the most treatment-refractory epithelial malignancies. Increased understanding of the underlying molecular aberrations in such tumors could provide insights leading to improved therapeutic approaches. In this study,
Autor:
Guizhong Liu, Sapna Vijayakumar, HuiFang Qiao, Stuart A. Aaronson, Randy Arroyave, Luca Grumolato, Gal Akiri
Publikováno v:
The Journal of Cell Biology
Genetic evidence indicates that Wnt signaling is critically involved in bone homeostasis. In this study, we investigated the functions of canonical Wnts on differentiation of adult multipotent human mesenchymal stem cells (hMSCs) in vitro and in vivo
Autor:
Sabrina Rotolo, Anna Bafico, Sapna Vijayakumar, Teresa Villanueva de la Torre, Zahid Hussain Khan
Publikováno v:
Molecular and Cellular Biology. 27:7291-7301
The canonical Wnt pathway plays a crucial role in embryonic development, and its deregulation is involved in human diseases. The LRP6 single-span transmembrane coreceptor is essential for transmission of canonical Wnt signaling. However, due to the l
Autor:
Aris N. Economides, Randy Arroyave, Phyllus Mong, Raksha Mudbhary, Sapna Vijayakumar, Romi Biswas, Stuart A. Aaronson, Luca Grumolato, Guizhong Liu
Wnt ligands signal through β-catenin and are critically involved in cell fate determination and stem/progenitor self-renewal. Wnts also signal through β-catenin-independent or noncanonical pathways that regulate crucial events during embryonic deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e91e06df03c606ac3486ef1c21432a
https://europepmc.org/articles/PMC2975928/
https://europepmc.org/articles/PMC2975928/
Autor:
Dawn Garcia, Chuck H. Hensel, Jacob Kagan, Todd Bracht, RuiHua Xiang, Mohua Banerjee, Sapna Vijayakumar, Susan L. Naylor
Publikováno v:
Genes, chromosomescancer. 44(4)
The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known w
Autor:
Sapna Vijayakumar, Luca Grumolato, Stefania Asciutti, Phyllus Mong, Gal Akiri, Stuart A. Aaronson
Publikováno v:
Gastroenterology. 142:S-327
Autor:
Sapna Vijayakumar, Dawn Garcia, Chuck H. Hensel, Mohua Banerjee, Todd Bracht, RuiHua Xiang, Jacob Kagan, Susan L. Naylor
Publikováno v:
Genes, Chromosomes & Cancer; Dec2005, Vol. 44 Issue 4, p365-372, 0p