Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sapna, Yadavilli"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In recent years, a set of immune receptors that interact with members of the nectin/nectin-like (necl) family has garnered significant attention as possible points of manipulation in cancer. Central to this axis, CD226, TIGIT, and CD96 represent liga
Externí odkaz:
https://doaj.org/article/de4cbba0e3fd4f49b752e681262c16cf
Autor:
Agathe Dubuisson, Jean‐Eudes Fahrner, Anne‐Gaëlle Goubet, Safae Terrisse, Nicolas Voisin, Charles Bayard, Sebastien Lofek, Damien Drubay, Delphine Bredel, Séverine Mouraud, Sandrine Susini, Alexandria Cogdill, Lucas Rebuffet, Elise Ballot, Nicolas Jacquelot, Vincent Thomas de Montpreville, Odile Casiraghi, Camélia Radulescu, Sophie Ferlicot, David J Figueroa, Sapna Yadavilli, Jeremy D Waight, Marc Ballas, Axel Hoos, Thomas Condamine, Bastien Parier, Christophe Gaudillat, Bertrand Routy, François Ghiringhelli, Lisa Derosa, Ingrid Breuskin, Mathieu Rouanne, Fabrice André, Cédric Lebacle, Hervé Baumert, Marie Wislez, Elie Fadel, Isabelle Cremer, Laurence Albiges, Birgit Geoerger, Jean‐Yves Scoazec, Yohann Loriot, Guido Kroemer, Aurélien Marabelle, Mélodie Bonvalet, Laurence Zitvogel
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Decision making in immuno‐oncology is pivotal to adapt therapy to the tumor microenvironment (TME) of the patient among the numerous options of monoclonal antibodies or small molecules. Predicting the best combinatorial regimen remains an
Externí odkaz:
https://doaj.org/article/67054ca5ed634665a330aa95af51b5fb
Autor:
Kieu-Suong Le, Patricia Amé-Thomas, Karin Tarte, Françoise Gondois-Rey, Samuel Granjeaud, Florence Orlanducci, Etienne D. Foucher, Florence Broussais, Reda Bouabdallah, Thierry Fest, Dominique Leroux, Sapna Yadavilli, Patrick A. Mayes, Luc Xerri, Daniel Olive
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1889-1900 (2018)
Abstract: A better characterization of T-cell subsets in the microenvironment of classical Hodgkin lymphoma (cHL) would help to develop immunotherapies. Using multicolor flow cytometry, we identified in 6 of 43 cHL tissue samples a previously unrecog
Externí odkaz:
https://doaj.org/article/9836bf4c7c5c4562a11be2b79c11a549
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c132032d92e87d5e6b477ea82f956e1
https://doi.org/10.1158/1078-0432.22461912
https://doi.org/10.1158/1078-0432.22461912
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Purpose: To assess the immunologic effects of dabrafenib and trametinib in vitro and to test whether trametinib potentiates or antagonizes the activity of immunomodulatory antibodies in vivo.Experimental Design: Immune effects of dabrafenib and trame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661aaed347926a54cf4ec666b3845e7f
https://doi.org/10.1158/1078-0432.c.6524868.v1
https://doi.org/10.1158/1078-0432.c.6524868.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary figure 2. Tumor gene expression changes measured by RT-PCR from mice treated with trametinib (T) in combination with the immunomodulator-targeting PD1 in the CT26 murine syngeneic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adc6344fb2c29f4cd0bb83e6b434a00
https://doi.org/10.1158/1078-0432.22461906.v1
https://doi.org/10.1158/1078-0432.22461906.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary figure 1. Tumor growth kinetics in individual mice treated with trametinib (T) in combination with the immunomodulator-targeting PD1 in the CT26 murine syngeneic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d034d716bb8479289c704eae1ae6b4
https://doi.org/10.1158/1078-0432.22461909.v1
https://doi.org/10.1158/1078-0432.22461909.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary tables S1-S6. Tumor gene expression data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49df5c367a4323164d8cf2bdc745816b
https://doi.org/10.1158/1078-0432.22461903.v1
https://doi.org/10.1158/1078-0432.22461903.v1
Autor:
Jong W Yu, Sabyasachi Bhattacharya, Niranjan Yanamandra, David Kilian, Hong Shi, Sapna Yadavilli, Yuliya Katlinskaya, Heather Kaczynski, Michael Conner, William Benson, Ashleigh Hahn, Laura Seestaller-Wehr, Meixia Bi, Nicholas J Vitali, Lyuben Tsvetkov, Wendy Halsey, Ashley Hughes, Christopher Traini, Hui Zhou, Junping Jing, Tae Lee, David J Figueroa, Sara Brett, Christopher B Hopson, James F Smothers, Axel Hoos, Roopa Srinivasan
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206223 (2018)
Mouse syngeneic tumor models are widely used tools to demonstrate activity of novel anti-cancer immunotherapies. Despite their widespread use, a comprehensive view of their tumor-immune compositions and their relevance to human tumors has only begun
Externí odkaz:
https://doaj.org/article/9e5e09f3952c4542877ca7afcf5e271e
Autor:
Jessica Perrin, Frank Wippich, Valeriia Sherina, Dmytro Dvornikov, Katharina Lupar, Murad M. Melhem, Patrick Hanafin, Jeremy Waight, Jong Yu, Sapna Yadavilli, Daniel Poeckel, Giovanna Bergamini
Publikováno v:
Cancer Research. 83:6647-6647
The ability to more faithfully mimic the tumor microenvironment (TME) of cancer patients offers a wide range of possibilities for non-clinical evaluation of anti-cancer therapeutics, including guidance for patient selection, dose, and combinations. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8675cb16c72ae4fc6d834b7c2b343101
https://doi.org/10.1158/1538-7445.am2023-6647
https://doi.org/10.1158/1538-7445.am2023-6647