Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Saparna Pai"'
Autor:
Tammy Allen, Maria Eugenia Castellanos, Paul Giacomin, Nadira D. Karunaweera, Andreas Kupz, Juan Carlos Lol, Dileep Sharma, Suchandan Sikder, Bemnet Tedla, Liza van Eijk, Danica Vojisavljevic, Guangzu Zhao, Saparna Pai
Publikováno v:
International Journal of Infectious Diseases, Vol 143, Iss , Pp 107014- (2024)
Tropical infectious diseases inflict an unacceptable burden of disease on humans living in developing countries. Although anti-pathogenic drugs have been widely used, they carry a constant threat of selecting for resistance. Vaccines offer a promisin
Externí odkaz:
https://doaj.org/article/e967e76a9cd94a109368f6690799a557
Autor:
Jim Qin, Michael D Lovelace, Andrew J Mitchell, Tania deKoning‐Ward, Georges ER Grau, Saparna Pai
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Objectives The immunologic events that build up to the fatal neurological stage of experimental cerebral malaria (ECM) are incompletely understood. Here, we dissect immune cell behaviour occurring in the central nervous system (CNS) when Pla
Externí odkaz:
https://doaj.org/article/95160bb3811246bfa4c106db3c59bd47
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract The global prevalence of respiratory infectious and inflammatory diseases remains a major public health concern. Prevention and management strategies have not kept pace with the increasing incidence of these diseases. The airway mucosa is th
Externí odkaz:
https://doaj.org/article/a694b16abfdb432abfccd56e0f37cf90
Autor:
Harindra D. Sathkumara, Saparna Pai, Michel de Jesús Aceves-Sánchez, Natkunam Ketheesan, Mario Alberto Flores-Valdez, Andreas Kupz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Tuberculosis (TB) is a major global public health problem causing significant mortality and morbidity. In addition to ~10.4 million cases of active TB annually, it is estimated that about two billion people are latently infected with Mycobacterium tu
Externí odkaz:
https://doaj.org/article/3b20906509e1489f8c7dbfd3a612cbf4
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/cac11924ca184ab0945f495cd481f6b2
Current evidence for a role of the Kynurenine pathway of tryptophan metabolism in Multiple Sclerosis
Autor:
Michael D. Lovelace, Bianca Varney, Gayathri Sundaram, Nunzio Franco, Mei Li Ng, Saparna Pai, Chai K. Lim, Bruce J. Brew
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The kynurenine pathway (KP) is the major metabolic pathway of the essential amino acid tryptophan (TRP). Stimulation by inflammatory molecules such as interferon-γ (IFN-γ) is the trigger for induction of the KP, driving a complex cascade of product
Externí odkaz:
https://doaj.org/article/f63391ce6f844246b57557d64f8d872e
Autor:
Saparna Pai, Jim Qin, Lois Cavanagh, Andrew Mitchell, Fatima El-Assaad, Rohit Jain, Valery Combes, Nicholas H Hunt, Georges E R Grau, Wolfgang Weninger
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004236 (2014)
During experimental cerebral malaria (ECM) mice develop a lethal neuropathological syndrome associated with microcirculatory dysfunction and intravascular leukocyte sequestration. The precise spatio-temporal context in which the intravascular immune
Externí odkaz:
https://doaj.org/article/4440c7935f8b4968b212bdb451ffca8b
Autor:
Yide Wong, Oyelola A. Adegboye, Matthew A. Field, Andreas Kupz, Dileep Sharma, Claire Loiseau, Michael J. Smout, Phurpa Wangchuk, Saparna Pai
Publikováno v:
Clin Microbiol Rev
About half of the world’s population and 80% of the world’s biodiversity can be found in the tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by endemic bacteria, viruses, parasites, and fungi. Such diseases ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b277976f7720953b0f570d60a1a1ca34
https://europepmc.org/articles/PMC8673330/
https://europepmc.org/articles/PMC8673330/
Autor:
Andrew J. Mitchell, Jim S. Qin, Saparna Pai, Michael D. Lovelace, Tania F. de Koning-Ward, Georges Er Grau
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Objectives: The immunologic events that build up to the fatal neurological stage of experimental cerebral malaria (ECM) are incompletely understood. Here, we dissect immune cell behaviour occurring in the central nervous system (CNS) when Plasmodium
Autor:
Jim, Qin, Michael D, Lovelace, Andrew J, Mitchell, Tania, de Koning-Ward, Georges Er, Grau, Saparna, Pai
Publikováno v:
Clinical & Translational Immunology
Objectives The immunologic events that build up to the fatal neurological stage of experimental cerebral malaria (ECM) are incompletely understood. Here, we dissect immune cell behaviour occurring in the central nervous system (CNS) when Plasmodium b