Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Saori Umeki"'
Autor:
Chung Chew Hwang, Saori Umeki, Masahito Kubo, Toshiharu Hayashi, Hiroshi Shimoda, Masami Mochizuki, Ken Maeda, Kenji Baba, Hiroko Hiraoka, Matt Coffey, Masaru Okuda, Takuya Mizuno
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73555 (2013)
The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutane
Externí odkaz:
https://doaj.org/article/f31d735bb2544fa8b15245950e11dad8
Autor:
Manabu Shirai, Hirotsugu Tsuchimochi, Takeshi Ogo, Yasushi Sakata, Tadakatsu Inagaki, Yusuke Manabe, Hatsue Ishibashi-Ueda, Takeshi Masaki, Manami Nishimura, Saori Umeki-Mizushima, James T. Pearson, Akiko Yamagishi, Yoshikazu Nakaoka, Tadamitsu Kishimoto, Atsushi Kumanogoh, Tomohiko Ishibashi, Ryotaro Asano, Makoto Okazawa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Inflammatory signals are thought to be crucial for the pathogenesis of PAH; however, the underlying mechanism is still largely unknown. In this study, we demonstrate that AHR makes a causal contribution to the pathogenesis of PAH, activa
Autor:
Takuma Yanase, Yoshiho Takeda, Takuya Mizuno, Masaya Igase, Yasuo Ema, Masaru Okuda, Saori Umeki, Hiroko Hiraoka
Publikováno v:
Veterinary and Comparative Oncology. 14:95-106
The cyclin-dependent kinase (CDK) inhibitor, flavopiridol, was tested as a potential new cancer therapeutic agent to treat canine lymphoma by examining its effect on cell growth of canine lymphoma cell lines in vitro. Flavopiridol induced profound ce
Autor:
Takeshi Masaki, Makoto Okazawa, Ryotaro Asano, Tadakatsu Inagaki, Tomohiko Ishibashi, Akiko Yamagishi, Saori Umeki-Mizushima, Manami Nishimura, Yusuke Manabe, Hatsue Ishibashi-Ueda, Manabu Shirai, Hirotsugu Tsuchimochi, Pearson, James T., Atsushi Kumanogoh, Yasushi Sakata, Takeshi Ogo, Tadamitsu Kishimoto, Yoshikazu Nakaoka
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/16/2021, Vol. 118 Issue 11, p1-12, 12p
Autor:
Saori Umeki, Shunsuke Noguchi, Masaru Okuda, Chung Chew Hwang, Masaya Igase, Matthew C. Coffey, Takuya Mizuno
Publikováno v:
Veterinary and Comparative Oncology. 14:61-73
Reovirus is a potent oncolytic virus in many human neoplasms that has reached phase II and III clinical trials. Our laboratory has previously reported the oncolytic effects of reovirus in canine mast cell tumour (MCT). In order to further explore the
Autor:
Masaru Okuda, Ryoichi Suzuki, Yasuo Ema, Yorihiro Nishimura, Takuya Mizuno, Saori Umeki, Masayuki Shimojima
Publikováno v:
Journal of Cellular Biochemistry. 114:1271-1285
P-selectin glycoprotein ligand-1 (PSGL-1) is an adhesive molecule that is known to be a ligand for P-selectin. An anti-adhesive property of PSGL-1 has not been previously reported. In this study, we show that PSGL-1 expression is anti-adhesive for ad
Autor:
Masaru Okuda, Saori Umeki, Yasuo Ema, Takuma Yanase, Hiroyuki Iwata, Takuya Mizuno, Masayuki Shimojima, Ryoichi Suzuki
Publikováno v:
Veterinary Immunology and Immunopathology. 142:119-125
Thirteen different monoclonal antibodies against canine P-selectin glycoprotein ligand-1 (cPSGL-1) were obtained by immunization of rats with cells of a canine lymphoma cell line (Ema). O-sialoglycoprotein endopeptidase treatment of Ema cells showed
Autor:
Hiroko Hiraoka, Masahito Kubo, Saori Umeki, Chung Chew Hwang, Toshiharu Hayashi, Masaru Okuda, Kenji Baba, Hiroshi Shimoda, Matthew C. Coffey, Masami Mochizuki, Ken Maeda, Takuya Mizuno
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73555 (2013)
PLoS ONE
PLoS ONE
The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutane
Autor:
Kenji Tani, Toshiharu Hayashi, Masahito Kubo, Jumpei Yamazaki, Takuya Mizuno, Masaru Okuda, Hajime Tsujimoto, Yasuo Ema, Saori Umeki, Yasuhiko Okamura, Ryoichi Suzuki, Hiroko Hiraoka
Publikováno v:
The Journal of veterinary medical science. 75(4)
Five novel, canine lymphoma cell lines (Ema, CLC, CLK, Nody-1 and UL-1) were established from dogs suffering from lymphoma and characterized in vitro and in vivo. All cell lines, except CLC, were characterized with T-cell phenotypes, by flow cytometr
Autor:
Takako Shimokawa Miyama, Saori Umeki, Masaharu Hisasue, Kenji Baba, Hiroko Hiraoka, Kumiko Sada, Hisashi Inokuma, Yasuyuki Endo, Takuya Mizuno, Masaru Okuda
Publikováno v:
The Journal of veterinary medical science. 73(10)
A 4-year-old, intact male Shiba dog was referred to Yamaguchi University Animal Medical Center, Yamaguchi, Japan, for the following complaints: anorexia, lethargy, intermittent fever, gingival bleeding and abdominal purpura. The dog presented with pe