Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Saori Uematsu"'
Autor:
Yifei Pan, Atsushi Hatano, Satoshi Ohno, Keigo Morita, Toshiya Kokaji, Yunfan Bai, Hikaru Sugimoto, Riku Egami, Akira Terakawa, Dongzi Li, Saori Uematsu, Hideki Maehara, Suguru Fujita, Hiroshi Inoue, Yuka Inaba, Atsushi J. Nagano, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Hepatic glucose metabolism serves dual purposes: maintaining glucose homeostasis and converting glucose into energy sources; however, the underlying mechanisms are unclear. We quantitatively measured liver metabolites, gene expression, and p
Externí odkaz:
https://doaj.org/article/3fcfca786a744fb18cb58409de0c7eef
Autor:
Hideki Maehara, Toshiya Kokaji, Atsushi Hatano, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Riku Egami, Takaho Tsuchiya, Haruka Ozaki, Keigo Morita, Masaki Shirai, Dongzi Li, Akira Terakawa, Saori Uematsu, Ken-ichi Hironaka, Satoshi Ohno, Hiroyuki Kubota, Hiromitsu Araki, Fumihito Miura, Takashi Ito, Shinya Kuroda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Each tissue has a dominant set of functional proteins required to mediate tissue-specific functions. Epigenetic modifications, transcription, and translational efficiency control tissue-dominant protein production. However, the coordination
Externí odkaz:
https://doaj.org/article/98436c9b09ae438fad492d1943038991
Autor:
Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-ichi Hironaka, Yuki Ito, Riku Egami, Saori Uematsu, Akira Terakawa, Yifei Pan, Hideki Maehara, Dongzi Li, Yunfan Bai, Takaho Tsuchiya, Haruka Ozaki, Hiroshi Inoue, Hiroyuki Kubota, Yutaka Suzuki, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Metabolic regulation in skeletal muscle is essential for blood glucose homeostasis. Obesity causes insulin resistance in skeletal muscle, leading to hyperglycemia and type 2 diabetes. In this study, we performed multiomic analysis of the ske
Externí odkaz:
https://doaj.org/article/dd5db8b9f47843dbacf9bbaaf001a016
Autor:
Saori Uematsu, Satoshi Ohno, Kaori Y. Tanaka, Atsushi Hatano, Toshiya Kokaji, Yuki Ito, Hiroyuki Kubota, Ken-ichi Hironaka, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103787- (2022)
Summary: Glucose homeostasis is maintained by modulation of metabolic flux. Enzymes and metabolites regulate the involved metabolic pathways. Dysregulation of glucose homeostasis is a pathological event in obesity. Analyzing metabolic pathways and th
Externí odkaz:
https://doaj.org/article/45123136428f459f9e3a0b9ac88e2a87
Autor:
Riku Egami, Toshiya Kokaji, Atsushi Hatano, Katsuyuki Yugi, Miki Eto, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-ichi Hironaka, Saori Uematsu, Akira Terakawa, Yunfan Bai, Yifei Pan, Takaho Tsuchiya, Haruka Ozaki, Hiroshi Inoue, Shinsuke Uda, Hiroyuki Kubota, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102217- (2021)
Summary: Systemic metabolic homeostasis is regulated by inter-organ metabolic cycles involving multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic diseases. The systemic landscape of dysregulated inter-organ metaboli
Externí odkaz:
https://doaj.org/article/16277b1822a647cf9a657d68049c4b26
Publikováno v:
The Biochemical journal. 479(6)
Cells change their metabolism in response to internal and external conditions by regulating the trans-omic network, which is a global biochemical network with multiple omic layers. Metabolic flux is a direct measure of the activity of a metabolic rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e7089b458a27378a656d39a92ce463
https://pubmed.ncbi.nlm.nih.gov/35356967
https://pubmed.ncbi.nlm.nih.gov/35356967
Autor:
Saori Uematsu, Satoshi Ohno, Kaori Y. Tanaka, Atsushi Hatano, Toshiya Kokaji, Yuki Ito, Hiroyuki Kubota, Ken-ichi Hironaka, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103787-(2022)
Summary: Glucose homeostasis is maintained by modulation of metabolic flux. Enzymes and metabolites regulate the involved metabolic pathways. Dysregulation of glucose homeostasis is a pathological event in obesity. Analyzing metabolic pathways and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1290727c22abe918fbb2495660d482a4
https://pubmed.ncbi.nlm.nih.gov/35243212
https://pubmed.ncbi.nlm.nih.gov/35243212
Autor:
Kaori Y. Tanaka, Toshiya Kokaji, Yutaka Suzuki, Satoshi Ohno, Shinya Kuroda, Yuki Ito, Keiichi I. Nakayama, Masaki Matsumoto, Saori Uematsu, Akiyoshi Hirayama, Hiroyuki Kubota, Ken-ichi Hironaka, Tomoyoshi Soga, Atsushi Hatano
SUMMARYGlucose homeostasis is maintained by modulation of metabolic flux. Enzymes and metabolites regulate the involved metabolic pathways. Dysregulation of glucose homeostasis is a pathological event in obesity. Analyzing metabolic pathways and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85ffb0726b8e0bb2bc794749411c93e
https://doi.org/10.1101/2021.06.21.449220
https://doi.org/10.1101/2021.06.21.449220
Autor:
Akira Terakawa, Satoshi Ohno, Katsuyuki Yugi, Haruka Ozaki, Yutaka Suzuki, Tomoyoshi Soga, Atsushi Hatano, Shinsuke Uda, Hiroyuki Kubota, Toshiya Kokaji, Akiyoshi Hirayama, Riku Egami, Takaho Tsuchiya, Masaki Matsumoto, Miki Eto, Keigo Morita, Yunfan Bai, Keiichi I. Nakayama, Masashi Fujii, Yifei Pan, Ken-ichi Hironaka, Saori Uematsu, Shinya Kuroda, Hiroshi Inoue
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102217-(2021)
iScience, Vol 24, Iss 3, Pp 102217-(2021)
Summary Systemic metabolic homeostasis is regulated by inter-organ metabolic cycles involving multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic diseases. The systemic landscape of dysregulated inter-organ metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb24a622c5f051b9b36972473d7cde0
https://pubmed.ncbi.nlm.nih.gov/33748705
https://pubmed.ncbi.nlm.nih.gov/33748705