Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Saori Tsuji"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Primary human hepatocytes are necessary to evaluate cytotoxicity, drug metabolism, and drug–drug interactions for candidate compounds in early-phase drug discovery and development. However, these analyses are often hampered by limited reso
Externí odkaz:
https://doaj.org/article/586c1d68c8994fc387df6a32a7dc4378
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156202 (2016)
The elimination of unfavorable chemicals from our environment and commercial products requires a sensitive and high-throughput in vitro assay system for drug-induced hepatotoxicity. Some previous methods for evaluating hepatotoxicity measure the amou
Externí odkaz:
https://doaj.org/article/eed92ebe609f4fe081c1c1e8c6cf7e5b
Autor:
Saori Tsuji, Fumihiko Kawamura, Musashi Kubiura, Ayaka Hayashi, Tetsuya Ohbayashi, Yasuhiro Kazuki, Christophe Chesné, Mitsuo Oshimura, Masako Tada
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104123 (2014)
Human adult hepatocytes expressing CYP3A4, a major cytochrome P450 enzyme, are required for cell-based assays to evaluate the potential risk of drug-drug interactions caused by transcriptional induction of P450 enzymes in early-phase drug discovery a
Externí odkaz:
https://doaj.org/article/49c39f1fa3b24521b3a0c4238e38bbb7
Publikováno v:
Proceedings of the 10th International Conference on Human-Agent Interaction.
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Laparoscopic surgery is less invasive but leads to a peculiar recurrence pattern. • Aspiration biopsy provides limited diagnostic accuracy in some cases. • Preoperative histological diagnosis should always be confirmed with D&C.
This study explores students’ perceptions about using Automated Writing Evaluation (AWE), Grammarly (a paid version), as a complementary instructional tool to teach and support writing from sources. Participants were second-year students (n=37) at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f54a1fbda809b37173d0ac4cd1961483
https://doi.org/10.14705/rpnet.2020.48.1186
https://doi.org/10.14705/rpnet.2020.48.1186
Autor:
Andrew Thompson, Saori Tsuji
The purpose of this pilot study was to investigate (1) students’ interest in reading English books, (2) students’ interest in using an online Virtual Library (VL), and (3) students’ experiences and preferences relating to the implementation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7fbffd90f3e1dc42c267978095ba9a
https://doi.org/10.14705/rpnet.2020.48.1209
https://doi.org/10.14705/rpnet.2020.48.1209
Autor:
Tomohiko, Takei, Erika, Takaki, Saori, Tsuji, Masayo, Onoue, Michiko, Yamashita, Emi, Yoshioka, Mayako, Goto, Lina, Tashima, Kimihiko, Ito, Kensuke, Hori
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(10)
We reviewed our clinical experience of olaparib treatment for patients with platinum-sensitive recurrent ovarian, fallopian tube, and peritoneal cancer. Of the 10 cases, the primary sites of cancer were the ovaries, fallopian tubes, and peritoneum in
Autor:
Fumihiko Kawamura, Yasuhiro Kazuki, Mitsuo Oshimura, Masako Tada, Hiroyuki Kugoh, Shota Okuyama, Mitsuhiko Osaki, Musashi Kubiura, Saori Tsuji
Publikováno v:
Pharmacology Research & Perspectives
The fields of drug discovery and regenerative medicine require large numbers of adult human primary hepatocytes. For this purpose, it is desirable to use hepatocyte‐like cells (HLCs) differentiated from human pluripotent stem cells (PSCs). Prematur
Autor:
Takafumi Ueyama, Keiko Ooeda, Mao Yamashita, Musashi Kubiura-Ichimaru, Shota Okuyama, Masako Tada, Fumihiko Kawamura, Akari Mine, Saori Tsuji
Publikováno v:
Pharmacology Research & Perspectives
Cytochrome P450 enzymes (CYP) function in drug metabolism in the liver. To evaluate numerous drug candidates, a high‐content screening (HCS) system with hepatocyte‐like cells (HLCs) that can replace adult human hepatocytes is required. Human hepa