Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Saori TAKAHASHI"'
Publikováno v:
International Journal of Agricultural Sustainability (2024)
The concept of Globally Important Agricultural Heritage Systems (GIAHS) evolved as a global collaborative endeavour to identify and protect a mosaic of traditional agro-ecosystems and landscapes that are rich in biodiversity and have both cultural an
Externí odkaz:
https://doaj.org/article/05c7abfa64db4dcfade854f746235c17
Autor:
Tomokazu Yamaguchi, Midori Hoshizaki, Takafumi Minato, Satoru Nirasawa, Masamitsu N. Asaka, Mayumi Niiyama, Masaki Imai, Akihiko Uda, Jasper Fuk-Woo Chan, Saori Takahashi, Jianbo An, Akari Saku, Ryota Nukiwa, Daichi Utsumi, Maki Kiso, Atsuhiro Yasuhara, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Yuji Fujino, Satoru Motoyama, Satoshi Nagata, Josef M. Penninger, Haruhiko Kamada, Kwok-Yung Yuen, Wataru Kamitani, Ken Maeda, Yoshihiro Kawaoka, Yasuhiro Yasutomi, Yumiko Imai, Keiji Kuba
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Endogenous ACE2 is a receptor for SARS-CoV-2 and a recombinant soluble ACE2 protein can inhibit SARS-CoV-2 infection acting as a decoy. Here the authors show that B38-CAP, an ACE2-like enzyme but not a decoy for the virus, is protective against SARS-
Externí odkaz:
https://doaj.org/article/37a0f877c7f0425f889b230ea8fdf522
Autor:
Maiko Abumiya, Naoto Takahashi, Saori Takahashi, Tomoko Yoshioka, Yoshihiro Kameoka, Masatomo Miura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The purpose of this study was to investigate the effects of SLC22A2 808G>T polymorphism and trough concentrations (C0) of bosutinib on serum creatinine in 28 patients taking bosutinib. At 1, 3, 6, 12, 24, and 36 months after administration,
Externí odkaz:
https://doaj.org/article/cddf7025ea95456eac4b8a2a0965cf7f
Autor:
Takafumi Minato, Satoru Nirasawa, Teruki Sato, Tomokazu Yamaguchi, Midori Hoshizaki, Tadakatsu Inagaki, Kazuhiko Nakahara, Tadashi Yoshihashi, Ryo Ozawa, Saki Yokota, Miyuki Natsui, Souichi Koyota, Taku Yoshiya, Kumiko Yoshizawa-Kumagaye, Satoru Motoyama, Takeshi Gotoh, Yoshikazu Nakaoka, Josef M. Penninger, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi, Keiji Kuba
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The enzyme ACE2 is involved in cardiac pathology and can counteract heart failure and other cardio-pulmonary diseases. Here the authors show that bacteria produce an ACE2-like enzyme that is effective in suppressing cardiac hypertrophy and fibrosis i
Externí odkaz:
https://doaj.org/article/d26136e7b956463b9d355114f88c8f40
Autor:
Takafumi Minato, Tomokazu Yamaguchi, Midori Hoshizaki, Satoru Nirasawa, Jianbo An, Saori Takahashi, Josef M Penninger, Yumiko Imai, Keiji Kuba
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270920 (2022)
Angiotensin-converting enzyme 2 (ACE2) is the carboxypeptidase to degrade angiotensin II (Ang II) to angiotensin 1-7 (Ang 1-7) and improves the pathologies of cardiovascular disease and acute respiratory distress syndrome (ARDS)/acute lung injury. B3
Externí odkaz:
https://doaj.org/article/e0e9f7bbbeab446c833a438f989f5bdb
Autor:
Xieyi Zhang, Wangyang Liu, Kazue Edaki, Yuta Nakazawa, Saori Takahashi, Hiroki Sunakawa, Kenta Mizoi, Takuo Ogihara
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 806 (2022)
Transcriptional factors, such as Snail, Slug, and Smuc, that cause epithelial-mesenchymal transition are thought to regulate the expression of Ezrin, Radixin, and Moesin (ERM proteins), which serve as anchors for efflux transporters on the plasma mem
Externí odkaz:
https://doaj.org/article/a4a1b3bb298f40b18e7b3a2e2217690e
Autor:
Tatsuya Ohhata, Kazuki Yamazawa, Asuka Miura-Kamio, Saori Takahashi, Satoshi Sakai, Yuka Tamura, Chiharu Uchida, Kyoko Kitagawa, Hiroyuki Niida, Ichiro Hiratani, Hisato Kobayashi, Hiroshi Kimura, Anton Wutz, Masatoshi Kitagawa
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108912- (2021)
Summary: The fine-scale dynamics from euchromatin (EC) to facultative heterochromatin (fHC) has remained largely unclear. Here, we focus on Xist and its silencing initiator Tsix as a paradigm of transcription-mediated conversion from EC to fHC. In mo
Externí odkaz:
https://doaj.org/article/4b9d9f2858de47159760643071866902
Autor:
Akiko Mita, Maiko Abumiya, Masatomo Miura, Takenori Niioka, Saori Takahashi, Tomoko Yoshioka, Yoshihiro Kameoka, Naoto Takahashi
Publikováno v:
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-8 (2018)
Abstract Purpose To investigate the exposure-toxicity relationship of bosutinib and to identify the target trough plasma concentration (C0). Methods The toxicity and C0 of bosutinib in Japanese chronic myeloid leukemia (CML) patients were monitored e
Externí odkaz:
https://doaj.org/article/63174987a30d4d5abe4393225503964d
Autor:
Shin-ichiro Takebayashi, Tyrone Ryba, Kelsey Wimbish, Takuya Hayakawa, Morito Sakaue, Kenji Kuriya, Saori Takahashi, Shin Ogata, Ichiro Hiratani, Katsuzumi Okumura, Masaki Okano, Masato Ogata
Publikováno v:
Cells, Vol 10, Iss 2, p 266 (2021)
Multiple epigenetic pathways underlie the temporal order of DNA replication (replication timing) in the contexts of development and disease. DNA methylation by DNA methyltransferases (Dnmts) and downstream chromatin reorganization and transcriptional
Externí odkaz:
https://doaj.org/article/34deeb6edbe3441688a6f882879d3d02
Autor:
Naoto Takahashi, Kaichi Nishiwaki, Chiaki Nakaseko, Nobuyuki Aotsuka, Koji Sano, Chikako Ohwada, Jun Kuroki, Hideo Kimura, Michihide Tokuhira, Kinuko Mitani, Kazuhisa Fujikawa, Osamu Iwase, Kohshi Ohishi, Fumihiko Kimura, Tetsuya Fukuda, Sakae Tanosaki, Saori Takahashi, Yoshihiro Kameoka, Hiroyoshi Nishikawa, Hisashi Wakita
Publikováno v:
Haematologica, Vol 103, Iss 11 (2018)
The purpose of this trial was to evaluate the efficacy of 2-year consolidation therapy with nilotinib, at a dose of 300 mg twice daily, for achieving treatment-free remission in chronic myeloid leukemia patients with a deep molecular response (BCR-AB
Externí odkaz:
https://doaj.org/article/d270522d9d4c488f9dc35f3bb6c9b3ce