Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Saori Otoguro"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:352-359
Petrolatum ointment, which is an oleaginous ointment, is generally produced through manufacturing processes such as melting, mixing, and cooling. In this type of semisolid formulation, the manufacturing conditions of each process are empirically know
Publikováno v:
YAKUGAKU ZASSHI. 137:757-762
The purpose of this study was to determine the density distribution of scored and round-faced tablets using synchrotron X-ray computed tomography. The tablets were made by direct compression of standard formulations. The density distribution of score
Autor:
Kozo Takayama, Yoshinori Onuki, Shunichi Utsumi, Naoto Uehara, Saori Otoguro, Yoshihiro Hayashi, Takahiro Miura, Yasuko Obata
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 63:890-900
The stress distribution of tablets after compression was simulated using a finite element method, where the powder was defined by the Drucker-Prager cap model. The effect of tablet shape, identified by the surface curvature, on the residual stress di
Autor:
Yasuko Obata, Yoshinori Onuki, Yoshihiro Hayashi, Saori Otoguro, Kozo Takayama, Hiroshi Mochida, Naoto Uehara
Publikováno v:
Drug development and industrial pharmacy. 42(1)
Background: Granule characteristics are some of the important intermediate qualities that determine tablet properties. However, the relationships between granule and tablet characteristics are poorly understood. The aim of this study was to elucidate
Autor:
Takahiro Miura, Yasuko Obata, Yoshinori Onuki, Yoshihiro Hayashi, Kozo Takayama, Saori Otoguro
Publikováno v:
Chemicalpharmaceutical bulletin. 62(11)
A multivariate statistical technique was applied to clarify the causal correlation between variables in the manufacturing process and the residual stress distribution of tablets. Theophylline tablets were prepared according to a Box-Behnken design us