Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Saori Ohmae"'
Autor:
Muneyoshi Futami, Keisuke Suzuki, Satomi Kato, Saori Ohmae, Yoshio Tahara, Masanori Nojima, Yoichi Imai, Takayuki Mimura, Yoshihiro Watanabe, Arinobu Tojo
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231896 (2020)
Cancer immunotherapy using chimeric antigen receptor-armed T (CAR T) cells have been shown to improve outcomes significantly in patients with hematological malignancies. However, cytokine release syndrome (CRS) remains a risk. CRS is characterized by
Externí odkaz:
https://doaj.org/article/cd02f8fc793149a99c6411bd33e19ae9
Autor:
Kenji Takemoto, Etsuro Hatano, Keiko Iwaisako, Masatoshi Takeiri, Naruto Noma, Saori Ohmae, Kan Toriguchi, Kazutaka Tanabe, Hirokazu Tanaka, Satoru Seo, Kojiro Taura, Keigo Machida, Norihiko Takeda, Shigehira Saji, Shinji Uemoto, Masataka Asagiri
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 777-787 (2014)
Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown t
Externí odkaz:
https://doaj.org/article/02e5661a7a984915b39c5072518433d7
Publikováno v:
Biochemical and biophysical research communications. 615
Age-associated increase in ectopic fat degeneration and fibrosis in the skeletal muscle contribute to muscle degradation and weakness. Quercetin is a bioactive flavonoid with anti-inflammatory and anti-obesity effects. Thus, we aimed to investigate t
Autor:
Hiroaki Fuji, Kazuya Izumi, Mineyoshi Aoyama, Masataka Asagiri, Masatoshi Takeiri, Moe Ito, Masayasu Toyomoto, Kojiro Taura, Kenji Takemoto, Hideto Yasutomi, Etsuro Hatano, Yasushi Ishihama, Norihiko Takeda, Naruto Noma, Saori Ohmae, Soichiro Iwaki, Shigeaki Hida, Masatoshi Hagiwara, Keiko Iwaisako, Shinji Uemoto, Satoru Seo
Publikováno v:
Biochemical and biophysical research communications. 503(2)
Osteoclasts play a crucial role in osteolytic bone diseases, such as osteoporosis, rheumatoid arthritis, periodontitis, Paget's disease of bone and bone metastatic tumors. Therefore, controlling osteoclast differentiation and function has been consid
Autor:
Mari Maeda-Yamamoto, Keiko Iwaisako, Kazuo Umezawa, Masataka Asagiri, Kenji Takemoto, Saori Ohmae, Nagahiro Minato, Naruto Noma, Siro Simizu, Masatoshi Takeiri
Publikováno v:
International Archives of Allergy and Immunology. 166:84-90
Background: Stimulation with antigen and IgE is known to activate NF-κB in mast cells. In the present research, we studied the role of NF-κB on cellular migration in mast cell-like RBL-2H3 cells and bone marrow-derived mast cells (BMMCs) using the
Autor:
Yasushi Ishihama, Naruto Noma, Masahiro Shinohara, Makoto Kawatani, Saori Ohmae, Kenji Takemoto, Hiroaki Fuji, Masatoshi Takeiri, Mineyoshi Aoyama, Masatoshi Hagiwara, Tomoko Fujita, Masayasu Toyomoto, Keiko Iwaisako, Norihiko Takeda, Masataka Asagiri
Publikováno v:
Scientific Reports
Osteoclasts degrade bone matrix proteins via the secretion of lysosomal enzymes. However, the precise mechanisms by which lysosomal components are transported and fused to the bone-apposed plasma membrane, termed ruffled border membrane, remain elusi
Autor:
Norihiko Takeda, Kenji Takemoto, Saori Ohmae, Satoru Seo, Shinji Uemoto, Masataka Asagiri, Hirokazu Tanaka, Naruto Noma, Shigehira Saji, Keigo Machida, Kazutaka Tanabe, Masatoshi Takeiri, Kojiro Taura, Etsuro Hatano, Keiko Iwaisako, Kan Toriguchi
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 777-787 (2014)
FEBS Open Bio, Vol 4, Iss C, Pp 777-787 (2014)
Graphical abstract
Highlights • RIPK-dependent necrosis is involved in acetaminophen (APAP)-induced hepatotoxicity. • Necrostatin-1 (Nec-1) protects mice against APAP-induced acute liver damage. • Nec-1 suppresses APAP-induced ROS generati
Highlights • RIPK-dependent necrosis is involved in acetaminophen (APAP)-induced hepatotoxicity. • Necrostatin-1 (Nec-1) protects mice against APAP-induced acute liver damage. • Nec-1 suppresses APAP-induced ROS generati
Autor:
Noriko Takegahara, Saori Ohmae, Toshihiko Toyofuku, Dong-Ju You, Myoung Ho Jang, Satoshi Nojima, Hyota Takamatsu, Tetsuya Kimura, Daisuke Ito, Yuji Yoshida, Tatsusada Okuno, Sujin Kang, Atsushi Kumanogoh
Publikováno v:
The Journal of Immunology. 188:1108-1116
The intestinal immune system is constantly challenged by commensal bacteria; therefore, it must maintain quiescence via several regulatory mechanisms. Although intestinal macrophages (Mϕs) have been implicated in repression of excessive inflammation
Autor:
Naruto, Noma, Masataka, Asagiri, Masatoshi, Takeiri, Saori, Ohmae, Kenji, Takemoto, Keiko, Iwaisako, Nagahiro, Minato, Mari, Maeda-Yamamoto, Siro, Simizu, Kazuo, Umezawa
Publikováno v:
International archives of allergy and immunology. 166(2)
Stimulation with antigen and IgE is known to activate NF-κB in mast cells. In the present research, we studied the role of NF-κB on cellular migration in mast cell-like RBL-2H3 cells and bone marrow-derived mast cells (BMMCs) using the NF-κB inhib