Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Sanz-Clemente A"'
Autor:
Andrew M. Chiu, Jiejie Wang, Michael P. Fiske, Pavla Hubalkova, Levi Barse, John A. Gray, Antonio Sanz-Clemente
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 332-341.e5 (2019)
Summary: In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are conne
Externí odkaz:
https://doaj.org/article/73f76fc17f9a441ead351253b1e1f347
Autor:
Sáenz Sanz, Clemente
Publikováno v:
Archivo Digital UPM
Universidad Politécnica de Madrid
Universidad Politécnica de Madrid
La habitación rupestre en la Península Ibérica conforma un amplio conjunto de manifestaciones cuyos orígenes son difíciles de dilucidar. Existen conjuntos primitivos, posiblemente horadados durante la Antigüedad Clásica y Tardía, y otros que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7eb4eec487c34034e3e02060fb0b1ae
https://doi.org/10.20868/upm.thesis.30318
https://doi.org/10.20868/upm.thesis.30318
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 607-614 (2013)
Synaptic activity triggers a profound reorganization of the molecular composition of excitatory synapses. For example, NMDA receptors are removed from synapses in an activity- and calcium-dependent manner, via casein kinase 2 (CK2) phosphorylation of
Externí odkaz:
https://doaj.org/article/1d36bef6b1e9466fbad22174eb7a5252
Autor:
Bo-Shiun Chen, John A. Gray, Antonio Sanz-Clemente, Zhe Wei, Eleanor V. Thomas, Roger A. Nicoll, Katherine W. Roche
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1120-1128 (2012)
Membrane-associated guanylate kinases (MAGUKs) are the major family of scaffolding proteins at the postsynaptic density. The PSD-MAGUK subfamily, which includes PSD-95, PSD-93, SAP97, and SAP102, is well accepted to be primarily involved in the synap
Externí odkaz:
https://doaj.org/article/fb714d238a724fab8a66524b370c6ebe
Akademický článek
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Autor:
M Dolores, Martín-de-Saavedra, Marc, Dos Santos, Lorenza, Culotta, Olga, Varea, Benjamin P, Spielman, Euan, Parnell, Marc P, Forrest, Ruoqi, Gao, Sehyoun, Yoon, Emmarose, McCoig, Hiba A, Jalloul, Kristoffer, Myczek, Natalia, Khalatyan, Elizabeth A, Hall, Liam S, Turk, Antonio, Sanz-Clemente, Davide, Comoletti, Stefan F, Lichtenthaler, Jeffrey S, Burgdorf, Maria V, Barbolina, Jeffrey N, Savas, Peter, Penzes
Publikováno v:
Neuron
While many neuronal, membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF) an
Autor:
M. Dolores Martín-de-Saavedra, Marc Dos Santos, Lorenza Culotta, Olga Varea, Benjamin P. Spielman, Euan Parnell, Marc P. Forrest, Ruoqi Gao, Sehyoun Yoon, Emmarose McCoig, Hiba A. Jalloul, Kristoffer Myczek, Natalia Khalatyan, Elizabeth A. Hall, Liam S. Turk, Antonio Sanz-Clemente, Davide Comoletti, Stefan F. Lichtenthaler, Jeffrey S. Burgdorf, Maria V. Barbolina, Jeffrey N. Savas, Peter Penzes
Publikováno v:
Neuron 110(4), 627-643.e9 (2022). doi:10.1016/j.neuron.2021.11.025
Although many neuronal membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF)
Akademický článek
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Autor:
Shuxi Liu, Marta Vieira, Antonio Sanz-Clemente, John D. Badger, Stephen F. Traynelis, Liang Zhou, Hongjie Yuan, Wei Lu, Katherine W. Roche
Publikováno v:
The Journal of Neuroscience. 37:4093-4102
NMDA receptors (NMDARs) are ionotropic glutamate receptors that are crucial for neuronal development and higher cognitive processes. NMDAR dysfunction is involved in a variety of neurological and psychiatric diseases; however, the mechanistic link be