Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Santosh Viswakarma"'
Autor:
Luca Rastelli, Sridharan Rajagopal, Chandru Gajendran, Naveen M. Sadhu, Zainuddin Mohd, Ramachandraiah Gosu, Dinorah Friedmann-Morvinski, Saravanan Kandan, Swarnakumari Birudukota, Srinivasan S, Krishnakumar V, Saif Wahid, Amir Siddiqui, Santosh Viswakarma, Ashwini Narayan, Rudresh G, Sadanand R. Mullurwar, Divsha Sher, Shahar Mansur, Dhanalakshmi Sivanandhan
Publikováno v:
Journal of Clinical Oncology. 40:2597-2597
2597 Background: Programmed Cell Death 1 (PD-1) protein plays a key role in inhibiting immune responses and enhancing self-tolerance via modulation of T-cell activity, inducing T-cell apoptosis and inhibiting apoptosis of regulatory T cells. PD-L1 al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::249387cb19bad3ea1b7c5187e58ab3c5
https://doi.org/10.1200/jco.2022.40.16_suppl.2597
https://doi.org/10.1200/jco.2022.40.16_suppl.2597
Autor:
Sreekala Nair, Mohd Zainuddin, Prashanthi Daram, Sridharan Rajagopal, Rudresh G, Basavaprabhu B, Amir Siddiqui, Reshma Dhkar, Dhanalakshmi Sivanandhan, Sunil Mohire, Krishnakumar, Santosh Viswakarma
Publikováno v:
Cancer Research. 80:1756-1756
Introduction: Lysine Specific Demethylase 1 (LSD1) is over-expressed in many cancers and down-regulation of LSD1 has been shown to effectively treat cancers by inducing re-expression of aberrantly silenced genes. Studies have shown that LSD1 may cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23939e83d5bfb60b45f2a8da6d757ad6
https://doi.org/10.1158/1538-7445.am2020-1756
https://doi.org/10.1158/1538-7445.am2020-1756
Publikováno v:
Journal of Medicinal Chemistry. 54:1191-1201
Synthesis and biological evaluation of orally active prodrugs (1a-d) of indomethacin are described. Prodrugs 1a-c showed a similar degree of anti-inflammatory activity, and prodrug 1d was found to be less potent than the parent drug indomethacin (1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d1e9fe66d4ff91544adfa43a4a6e8f
https://doi.org/10.1021/jm101085j
https://doi.org/10.1021/jm101085j
Publikováno v:
Journal of Medicinal Chemistry; Mar2011, Vol. 54 Issue 5, p1202-1210, 9p
Publikováno v:
Journal of Medicinal Chemistry; Mar2011, Vol. 54 Issue 5, p1191-1201, 11p