Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Santosh L. Vishwakarma"'
Autor:
Dinesh Thiagaraj, Sridharan Rajagopal, Rudresh G, Prasanthi Daram, Mohd Zainuddin, Naveen Sadhu, Chandru G, Amir Siddiqui, Neha Ks, Basava Prabhu, Subramanyam J Tantry, Santosh L. Vishwakarma, Saif wahid, Sreekala Nair, Krishnakumar, Sivanandhan Dhanalakshmi
Publikováno v:
Blood. 136:29-29
Introduction: Lysine specific demethylase 1 (LSD1) and histone deacetylases (HDACs) are known to modulate the expression of several disease specific genes as part of repressor complexes, including CoREST. In addition, they also have complex mutually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9af4ae3c111ccb48b58ab4edbc27b6e
https://doi.org/10.1182/blood-2020-142685
https://doi.org/10.1182/blood-2020-142685
Autor:
Santosh L. Vishwakarma, G Vijaykant, Pranesha Shetty, Shridhar Narayanan, Uma Maheswari Krishnan, J. Raghul, Nagaraj M. Kulkarni, Yeshwant Kurhe, Shilpee Chaudhary, Jeyamurugan Mookkan, Mallikarjun S Jaji, B Navin Rajesh
Publikováno v:
Pharmaceutical Biology. 53:1110-1117
Metabolic syndrome and non-alcoholic fatty liver disease (NAFLD) are the emerging co-morbidities of skin inflammation. Occurrence of skin inflammation such as psoriasis is substantially higher in NAFLD patients than normal. Currently, there are no an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31146dd63ff75c63a9389c73cfbe33b9
https://doi.org/10.3109/13880209.2014.960944
https://doi.org/10.3109/13880209.2014.960944
Autor:
Ganapavarapu Veera Ragh Sharma, Sanjeev Saxena, Narasimhan Kilambi, Lavanya Andiappan, C.V. Srinivasan, Gopalan Balasubramanian, Saravanakumar Natarajan, Shridhar Narayanan, Santosh L. Vishwakarma, Fakrudeen Ali Ahamed Nazumudeen, Thirunavukkarasu Sappanimuthu, Sukunath Narayanan, Sridharan Rajagopal, Saravanan Thirunavukkarasu, Shamundeeswari Sundaram, Naresh Sivaraman
Publikováno v:
Bioorganicmedicinal chemistry. 24(22)
Herein we report the synthesis, PDE-4B and TNF-α inhibitory activities of a few dibenzo[b,d]furan-1-yl-thiazole derivatives. The hydroxycyclohexanol amide derivatives 14, 18, 24, 29, 31 and 33 exhibited promising in vitro PDE-4B and TNF-α inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9aabc52be0786b4cf96bb8f1e2b96c
https://pubmed.ncbi.nlm.nih.gov/27713015
https://pubmed.ncbi.nlm.nih.gov/27713015
Autor:
Anjana A. Adhyapak, Suraj Tubachi, Vijay Benade, Vijay Hebballi, Santosh L. Vishwakarma, Nagaraj M. Kulkarni, Saudagar Mohammad Ashfaque, B.S. Thippeswamy, Farhin R. Khan, Mahamad Yunnus A. Mahat, Basangouda M. Patil
Publikováno v:
European Journal of Pharmacology. 642:169-176
Kaempferol has been reported to inhibit nitric oxide synthase and cyclooxygenase enzymes in animal models. The present study was designed to investigate whether kaempferol modulates the cyclooxygenase pathway via inhibition of nitric oxide production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ddac9cf8cce3fe53032a9452856047
https://doi.org/10.1016/j.ejphar.2010.05.062
https://doi.org/10.1016/j.ejphar.2010.05.062
Publikováno v:
Journal of Planar Chromatography – Modern TLC. 17:128-131
Swertiamarin is a secoiridoid glucoside present in members of the Gentianaceae family, including Swertia chirata (Wall) Clarke, S. japonica Makino, S. angustifolia Buch.-Ham.ex D. Don, and Enicostemma littorale Blume. It has antidepressant and antich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c2236652d0567e218884283192fbadf
https://doi.org/10.1556/jpc.17.2004.2.8
https://doi.org/10.1556/jpc.17.2004.2.8
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:101-105
The fresh and dried rhizome of Zingiber officinale Roscoe (commonly known as ginger) is widely used in traditional medicine. We have studied the effect of the juice of Z. officinale (4 mL kg−1, p.o. daily) for 6 weeks on streptozotocin (STZ)-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47029b5df2526919acc13df54b0a886
https://doi.org/10.1211/0022357022403
https://doi.org/10.1211/0022357022403
Publikováno v:
Pharmaceutical Biology. 42:400-403
We report a simple method for the isolation of swertiamarin, a secoiridoid glycoside, from the whole plant of Enicostemma littorale Blume. Methanol extract of defatted plant material when treated with diethyl ether gave a precipitate containing swert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee31b15be3397fadaf563f941cdf7581
https://doi.org/10.1080/13880200490885095
https://doi.org/10.1080/13880200490885095
Publikováno v:
Oriental Pharmacy and Experimental Medicine. 3:196-204
Aqueous extract of Enicostemma littorale is reported to have antidiabetic activity. In the present investigation, we studied the effect of aqueous extract of E. littorale and its different fractions i.e., toluene, chloroform, ethyl acetate, n-butanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd81303492f80a7b5b7ab406fbfdb0c2
https://doi.org/10.3742/opem.2003.3.4.196
https://doi.org/10.3742/opem.2003.3.4.196
Autor:
G. Vijaykanth, Uma Maheswari Krishnan, J. Raghul, Santosh L. Vishwakarma, Nagaraj M. Kulkarni, Milind M. Muley, Neetin Kumar D. Reddy, Jeyamurugan Mookkan, Navin B. Rajesh, Shridhar Narayanan, Mallikarjun S Jaji
Publikováno v:
Archives of pharmacal research. 38(6)
Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor used in the treatment of atherosclerosis and dyslipidemia. Studies have evaluated the utility of statins in the treatment of skin inflammation but with varied results. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed77f802608bac3b8b9dfb6745c868f
https://pubmed.ncbi.nlm.nih.gov/25311664
https://pubmed.ncbi.nlm.nih.gov/25311664
Autor:
Shridhar Narayanan, Arun Shastry, Santosh L. Vishwakarma, Jayanarayan Kulathingal, J. Raghul, Virendra Kachhadia, Navin B. Rajesh, Sridharan Rajgopal, Milind M. Muley, Gopalan Balasubramanian, Narasimhan Kilambi, Ambrish Saxena, G. Vijaykanth, Pankaj Singh, Suresh Rathinasamy, Lakshmi R. Iyer
Publikováno v:
International immunopharmacology. 16(1)
Epigenetic modifications represent a promising new approach to modulate cell functions as observed in autoimmune diseases. Emerging evidence suggests the utility of HDAC inhibitors in the treatment of chronic immune and inflammatory disorders. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e885a38b6c412d1de4f724dd532cc202
https://pubmed.ncbi.nlm.nih.gov/23541634
https://pubmed.ncbi.nlm.nih.gov/23541634