Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Santosh K. Sahoo"'
Autor:
Yen-Ju Cheng, Santosh K. Sahoo, Hsiao Chieh Chou, Fong Yi Cao, Chia Wei Wang, Wen Ching Yin, Tze Gang Hsu, Ching Li Huang, Shao Ling Chang
Publikováno v:
Organic Letters. 23:1692-1697
We discovered a unique synthetic route to construct 2H-pyran-containing tetracyclic dithienocyclopentapyran (DTCP) and dibenzocyclopentapyran (DBCP) architectures. The synthesis involves an acid-induced dehydration cyclization followed by a [1,5] hyd
Publikováno v:
Organic Letters. 22:2318-2322
Pd(II)-catalyzed dehydrogenative Heck olefination of selenophenes with a broad olefinic substrate scope and high functional group tolerance is demonstrated. Carbonyl-substituted and phenyl-substituted olefins with electron-donating (D) and electron-a
Autor:
Santosh K. Sahoo, Siva N. R. Gajula, Mohammad N. Ahmad, Grace Kaul, Srinivas Nanduri, Rajesh Sonti, Arunava Dasgupta, Sidharth Chopra, Venkata M. Yaddanapudi
Publikováno v:
Archiv der Pharmazie. 355:2200168
The quinoline moiety remains a privileged antitubercular (anti-TB) pharmacophore, whereas 8-nitrobenzothiazinones are emerging potent antimycobacterial agents with two investigational candidates in the clinical pipeline. Herein, we report the synthes
Autor:
Claudiu T. Supuran, Abhishek Choli, Andrea Angeli, Priti Singh, Mohammed Arifuddin, Venkata Madhavi Yaddanapudi, Baijayantimala Swain, Santosh K. Sahoo
Publikováno v:
Archiv der Pharmazie. 355:2100333
Indole is a privileged moiety with a wide range of bioactivities, making it a popular scaffold in drug design and development studies as well as in synthetic chemistry. Here, novel urea derivatives of indole, containing sulfonamide at position-3 of i
Autor:
Santosh K. Sahoo, Venkata Madhavi Yaddanapudi, Arunava Dasgupta, Mohammad Naiyaz Ahmad, Srinivas Nanduri, G. Kaul, Bandela Rani, Nikhil Baliram Gaikwad, Manjulika Shukla, Sidharth Chopra
Publikováno v:
European Journal of Medicinal Chemistry. 222:113580
In search of novel therapeutic agents active against emerging drug-resistant Mycobacterium tuberculosis and to counter the long treatment protocol of existing drugs, herein we present synthesis and biological evaluation of a new series of 5-phenyl-3-
Autor:
Krishna Nirmale, Manjulika Shukla, Arunava Das Gupta, Sidharth Chopra, Madhavi Venkata Yaddanapudi, Grace Kaul, Mohammad N. Ahmad, Srinivas Nanduri, Santosh K. Sahoo, Nikhil Baliram Gaikwad
Publikováno v:
Archiv der Pharmazie. 354:2000349
Mycobacterium tuberculosis (Mtb) is one of the most dangerous pathogens affecting immunocompetent and immunocompromised patients worldwide. Novel molecules, which are efficient and can reduce the duration of therapy against drug-resistant strains, ar
Autor:
Santosh K. Sahoo
Publikováno v:
Tetrahedron Letters. 57:3476-3480
An unprecedented formation of benzylic sp(3)C-sp(3)C coupled dibenzylic products has been illustrated. The reactions have been carried out in the presence of three oxidizing reagents, i.e., diacetoxy-iodobenzene (IBDA), N-fluorobenzenesulfonimide (NF
Publikováno v:
ACS Catalysis. 6:3575-3579
Development of meta-C–H functionalization reactions at room temperature continues to be a tough challenge. Use of a phosphonate linkage allowed a Pd (II)-catalyzed meta-C–H functionalization at room temperature while incorporating a cyanophenol-b
Autor:
Santosh K. Sahoo
Publikováno v:
Journal of Chemical Sciences. 127:2151-2157
A relative synthetic strategy toward intermolecular oxidative C −Chalcogen bond formation of alkanes has been illustrated using both Cu(II) assisted vs Cu(II) free conditions. This led to construction of a comparative study of hydrocarbon benzylic
Publikováno v:
European Journal of Organic Chemistry. 2015:7534-7543
The in situ generated bis-thioureas obtained by treating aryl/alkyl isothiocyanates with aliphatic 1,2-diamines, upon treatment with CuI or CuII salts, depending on their quantity and the reaction conditions, furnished either imidazolidinecarbothioam