Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Santosh K, Dasari"'
Autor:
Christopher J. LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S. Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K. Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B. Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J. Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K. Sood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Antiangiogenic treatment targeting the vascular endothelial growth factor (VEGF) pathway is a powerful tool to combat tumor growth and progression; however, drug resistance frequently emerges. We identify CD5L (CD5 antigen-like precursor) as
Externí odkaz:
https://doaj.org/article/a4cffeff90ca418b8ed9c213a7bf3531
Autor:
Michael H. McGuire, Shelley M. Herbrich, Santosh K. Dasari, Sherry Y. Wu, Ying Wang, Rajesha Rupaimoole, Gabriel Lopez-Berestein, Keith A. Baggerly, Anil K. Sood
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 127-137 (2019)
Background: Investigations into the function of non-promoter DNA methylation have yielded new insights into the epigenetic regulation of gene expression. However, integrated genome-wide non-promoter DNA methylation and gene expression analyses across
Externí odkaz:
https://doaj.org/article/b4067c0beb384d1fb79d6c599e204a48
Autor:
Shaolin Ma, Michael H. McGuire, Lingegowda S. Mangala, Sanghoon Lee, Elaine Stur, Wen Hu, Emine Bayraktar, Alejandro Villar-Prados, Cristina Ivan, Sherry Y. Wu, Akira Yokoi, Santosh K. Dasari, Nicholas B. Jennings, Jinsong Liu, Gabriel Lopez-Berestein, Prahlad Ram, Anil K. Sood
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108726- (2021)
Summary: Tumor and stromal interactions consist of reciprocal signaling through cytokines, growth factors, direct cell-cell interactions, and extracellular vesicles (EVs). Small EVs (≤200 nm) have been considered critical messengers of cellular com
Externí odkaz:
https://doaj.org/article/3d6a230927204553ac2d7099cfaf159f
Autor:
Yang Li, Shanshan Yang, Nouara C. Sadaoui, Wei Hu, Santosh K. Dasari, Lingegowda S. Mangala, Yunjie Sun, Shuangtao Zhao, Linghua Wang, Yuan Liu, Lois M. Ramondetta, Ke Li, Chong Lu, Yu Kang, Steve W. Cole, Susan K. Lutgendorf, Anil K. Sood
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101289- (2020)
Summary: Chronic stress-related hormones modulate tumor pathogenesis at multiple levels; however, the molecular pathways involved in stress and cervical cancer progression are not well understood. We established a preclinical orthotopic mouse model o
Externí odkaz:
https://doaj.org/article/aafb654e476b47ddb4c1d3c01818360f
Autor:
Anil K. Sood, Prahlad T. Ram, Shannon N. Westin, Yosef Landesman, Robert L. Coleman, Clifford Stephan, Paola Amero, Yunfei Wen, Deanna Glassman, Sujanitha Umamaheswaran, Mark Kim, Cristina Ivan, Mary Sobieski, Reid T. Powell, Nghi Nguyen, Santosh K. Dasari, Emine Bayraktar, Robiya Joseph, Elaine Stur, Shaolin Ma, Cristian Rodriguez-Aguayo, Katelyn F. Handley
CRM1 inhibitors have demonstrated antitumor effects in ovarian and other cancers; however, rational combinations are largely unexplored. We performed a high-throughput drug library screen to identify drugs that might combine well with selinexor in ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa7fbe99d046f9834b99cb2a0e34ac
https://doi.org/10.1158/1535-7163.c.6543538.v1
https://doi.org/10.1158/1535-7163.c.6543538.v1
Autor:
Anil K. Sood, Keith A. Baggerly, Jing Wang, Menashe Bar-Eli, Eric Jonasch, Sherry Y. Wu, Einav Shoshan, Cristina Ivan, Wencai Ma, Emine Bayraktar, Lingegowda S. Mangala, Yunfei Wen, Hui Yao, Santosh K. Dasari, Michael H. McGuire
Investigations into the function of nonpromoter DNA methylation have yielded new insights into epigenetic regulation of gene expression. Previous studies have highlighted the importance of distinguishing between DNA methylation in discrete functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f4684c8362c9bb9e84df783de7f162
https://doi.org/10.1158/1541-7786.c.6545165.v1
https://doi.org/10.1158/1541-7786.c.6545165.v1
Autor:
Anil K. Sood, Keith A. Baggerly, Jing Wang, Menashe Bar-Eli, Eric Jonasch, Sherry Y. Wu, Einav Shoshan, Cristina Ivan, Wencai Ma, Emine Bayraktar, Lingegowda S. Mangala, Yunfei Wen, Hui Yao, Santosh K. Dasari, Michael H. McGuire
Supplementary Table from Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54afb9e21c5106c451038fac2137de92
https://doi.org/10.1158/1541-7786.22526654
https://doi.org/10.1158/1541-7786.22526654
Autor:
Anil K. Sood, Prahlad T. Ram, Shannon N. Westin, Yosef Landesman, Robert L. Coleman, Clifford Stephan, Paola Amero, Yunfei Wen, Deanna Glassman, Sujanitha Umamaheswaran, Mark Kim, Cristina Ivan, Mary Sobieski, Reid T. Powell, Nghi Nguyen, Santosh K. Dasari, Emine Bayraktar, Robiya Joseph, Elaine Stur, Shaolin Ma, Cristian Rodriguez-Aguayo, Katelyn F. Handley
Revised Supplementary Data Demonstrating All Supplementary Figures 1-6 and Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b392d6003debfc0c061f1af4e291b028
https://doi.org/10.1158/1535-7163.22522975.v1
https://doi.org/10.1158/1535-7163.22522975.v1
Autor:
Yutuan Wu, Nicholas B. Jennings, Yunjie Sun, Santosh K. Dasari, Emine Bayraktar, Sara Corvigno, Elaine Stur, Deanna Glassman, Lingegowda S. Mangala, Adrian Lankenau Ahumada, Shannon N. Westin, Anil K. Sood, Wei Hu
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:803-821
Purpose Tumor-associated macrophages (TAMs) are known to contribute to adaptive resistance to anti-vascular endothelial growth factor (VEGF) antibody (AVA) therapy in ovarian cancer. BET (bromodomain and extra-terminal domain) inhibitors (BETi) may h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a6678cc91f12018bd6ecf568470d548
https://doi.org/10.1007/s00432-021-03885-z
https://doi.org/10.1007/s00432-021-03885-z
Autor:
Santosh K. Dasari, Robiya Joseph, Sujanitha Umamaheswaran, Lingegowda S. Mangala, Emine Bayraktar, Cristian Rodriguez-Aguayo, Yutuan Wu, Nghi Nguyen, Reid T. Powell, Mary Sobieski, Yuan Liu, Mamur A. Chowdhury, Paola Amero, Clifford Stephan, Gabriel Lopez-Berestein, Shannon N. Westin, Anil K. Sood
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3915
Volume 24
Issue 4
Pages: 3915
EphA2 tyrosine kinase is upregulated in many cancers and correlated with poor survival of patients, including those with endometrial cancer. EphA2-targeted drugs have shown modest clinical benefit. To improve the therapeutic response to such drugs, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5cc622b462a9693e1d680e23442560