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pro vyhledávání: '"Santosh C. Hodawadekar"'
Autor:
Santosh C. Hodawadekar, Pawel Bieganowski, P.N. Garrison, Gérard Faye, Charles Brenner, Larry D. Barnes
Publikováno v:
Journal of Biological Chemistry. 277:10852-10860
The histidine triad superfamily of nucleotide hydrolases and nucleotide transferases consists of a branch of proteins related to Hint and Aprataxin, a branch of Fhit-related hydrolases, and a branch of galactose-1-phosphate uridylyltransferase (GalT)
Publikováno v:
Journal of Biological Chemistry. 275:4555-4560
Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins, binds and cleaves diadenosine polyphosphates and functions as a tumor suppressor in human epithelial cancers. Function of Fhit in tumor suppression does not require dia