An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction

Autor: Santoscoy, Miguel C., Espinoza, Paula, De La Cruz, Demitri, Mahamdeh, Mohammed, Starr, Jacqueline R., Patel, Nikita, Maguire, Casey A.

Publikováno v: In Molecular Therapy - Methods & Clinical Development 8 June 2023 29:532-540

A systematic framework for using membrane metrics for strain engineering

Autor: Santoscoy, Miguel C., Jarboe, Laura R.

Publikováno v: In Metabolic Engineering July 2021 66:98-113

Allelic variation of Escherichia coli outer membrane protein A: Impact on cell surface properties, stress tolerance and allele distribution.

Autor: Liao, Chunyu¹ (AUTHOR), Santoscoy, Miguel C.² (AUTHOR), Craft, Julia³ (AUTHOR), Anderson, Chiron³ (AUTHOR), Soupir, Michelle L.⁴ (AUTHOR), Jarboe, Laura R.^1,2 (AUTHOR) ljarboe@iastate.edu

Publikováno v: PLoS ONE. 10/13/2022, Vol. 17 Issue 10, p1-21. 21p.

Distinguishing between metabolically active and dormant bacteria on paper.

Autor: Hice, Stephanie A.¹, Santoscoy, Miguel C.², Soupir, Michelle L.³, Cademartiri, Rebecca^2,4 rcademar@iastate.edu

Publikováno v: Applied Microbiology & Biotechnology. Jan2018, Vol. 102 Issue 1, p367-375. 9p.

Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice.

Autor: Santoscoy MC; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116., Espinoza P; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116., Hanlon KS; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116.; University College London, London, United Kingdom., Yang L; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Havard Medical School, Boston, MA 02121., Nieland L; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Department of Neurosurgery, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Ng C; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116., Badr CE; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116., Hickman S; Department of Medicine, Center for Immunology and Inflammatory Disease, Massachusetts General Hospital, Boston, USA., de la Cruz D; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116., Griciuc A; Genetics and Aging Research Unit, McCance Center for Brain Health, Mass General Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Elkhoury J; Department of Medicine, Center for Immunology and Inflammatory Disease, Massachusetts General Hospital, Boston, USA., Bennett RE; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Harvard Medical School, Boston, MA, 02116., Shen S; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Havard Medical School, Boston, MA 02121., Maguire CA; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115.; Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA, 02129.; Harvard Medical School, Boston, MA, 02116.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27.