The fungicide cymoxanil impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition.

Autor: Mendes F; CBMA - Centre of Molecular and Environmental Biology/ARNET - Aquatic Research Network, Department of Biology, School of Sciences, University of Minho, Braga, Portugal., Santos-Pereira C; CEB - Centre of Biological Engineering, University of Minho, Braga, Portugal.; LABBELS - Associate Laboratory, Braga, Portugal., Vieira TF; UCIBIO/REQUIMTE, BioSIM - Departamento de Medicina, Faculdade de Medicina da Universidade Do Porto, Portugal.; Associate Laboratory i4HB - Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, Portugal., Martins Pinto M; CNRS, UMR 5095, Institut de Biochimie et Génétique Cellulaires, Bordeaux, France., Castro BB; CBMA - Centre of Molecular and Environmental Biology/ARNET - Aquatic Research Network, Department of Biology, School of Sciences, University of Minho, Braga, Portugal.; IBS - Institute of Science and Innovation for Bio-Sustainability, School of Sciences, University of Minho, Braga, Portugal., Sousa SF; UCIBIO/REQUIMTE, BioSIM - Departamento de Medicina, Faculdade de Medicina da Universidade Do Porto, Portugal.; Associate Laboratory i4HB - Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, Portugal., Sousa MJ; CBMA - Centre of Molecular and Environmental Biology/ARNET - Aquatic Research Network, Department of Biology, School of Sciences, University of Minho, Braga, Portugal.; IBS - Institute of Science and Innovation for Bio-Sustainability, School of Sciences, University of Minho, Braga, Portugal., Devin A; CNRS, UMR 5095, Institut de Biochimie et Génétique Cellulaires, Bordeaux, France., Chaves SR; CBMA - Centre of Molecular and Environmental Biology/ARNET - Aquatic Research Network, Department of Biology, School of Sciences, University of Minho, Braga, Portugal.

Publikováno v: FEBS letters [FEBS Lett] 2024 Jul; Vol. 598 (13), pp. 1655-1666. Date of Electronic Publication: 2024 May 15.

Enhancement of Acetate-Induced Apoptosis of Colorectal Cancer Cells by Cathepsin D Inhibition Depends on Oligomycin A-Sensitive Respiration.

Autor: Alves S; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal., Santos-Pereira C; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal., Oliveira CSF; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal., Preto A; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal., Chaves SR; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal., Côrte-Real M; CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4710-057 Braga, Portugal.

Publikováno v: Biomolecules [Biomolecules] 2024 Apr 12; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 12.

Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells.

Autor: Ferreira D; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; LABBELS-Associate Laboratory, 4710-057 Braga, Portugal., Santos-Pereira C; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; LABBELS-Associate Laboratory, 4710-057 Braga, Portugal., Costa M; Life and Health Sciences Research Institute (ICVS), University of Minho, Campus of Gualtar, Braga, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Afonso J; Life and Health Sciences Research Institute (ICVS), University of Minho, Campus of Gualtar, Braga, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Yang S; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA., Hensel J; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA., McAndrews KM; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA., Longatto-Filho A; Life and Health Sciences Research Institute (ICVS), University of Minho, Campus of Gualtar, Braga, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo, Brazil; Laboratory of Medical Investigation (LIM 14), Faculty of Medicine, São Paulo State University, S. Paulo, Brazil., Fernandes R; HEMS-Histology and Electron Microscopy Service, IBMC/I3S, Universidade do Porto, 4200-135 Porto, Portugal., Melo JB; Cytogenetics and Genomics Laboratory, Faculty of Medicine, University of Coimbra, Portugal; Center of Investigation on Environment Genetics and Oncobiology, Faculty of Medicine, University of Coimbra, Portugal., Baltazar F; Life and Health Sciences Research Institute (ICVS), University of Minho, Campus of Gualtar, Braga, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Moreira JN; CNC-Center for Neurosciences and Cell Biology, Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Faculty of Medicine (Polo 1), Rua Larga, 3004-504 Coimbra, Portugal; Univ Coimbra-University of Coimbra, CIBB, Faculty of Pharmacy, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal., Kalluri R; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA; School of Bioengineering, Rice University, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Rodrigues LR; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; LABBELS-Associate Laboratory, 4710-057 Braga, Portugal. Electronic address: lrmr@deb.uminho.pt.

Publikováno v: Biomaterials advances [Biomater Adv] 2023 Nov; Vol. 154, pp. 213643. Date of Electronic Publication: 2023 Sep 28.

Bovine Lactoferrin-Loaded Plasmonic Magnetoliposomes for Antifungal Therapeutic Applications.

Autor: Pereira M; Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.; LaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal., Rodrigues ARO; Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.; LaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal., Amaral L; Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal., Côrte-Real M; Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal., Santos-Pereira C; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal., Castanheira EMS; Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.; LaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 Aug 19; Vol. 15 (8). Date of Electronic Publication: 2023 Aug 19.

Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase.

Autor: Santos-Pereira C; Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal; Centre of Biological Engineering (CEB), Department of Biological Engineering, University of Minho, 4710-057 Braga, Portugal; LABBELS - Associate Laboratory, Braga/Guimarães, Portugal., Guedes JP; Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal., Ferreira D; Centre of Biological Engineering (CEB), Department of Biological Engineering, University of Minho, 4710-057 Braga, Portugal; LABBELS - Associate Laboratory, Braga/Guimarães, Portugal., Rodrigues LR; Centre of Biological Engineering (CEB), Department of Biological Engineering, University of Minho, 4710-057 Braga, Portugal; LABBELS - Associate Laboratory, Braga/Guimarães, Portugal., Côrte-Real M; Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal. Electronic address: mcortereal@bio.uminho.pt.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2022 Nov 01; Vol. 220, pp. 1589-1604. Date of Electronic Publication: 2022 Sep 16.