Výsledky vyhledávání - "Santos-Moore A"

Modulation of bleomycin-induced pulmonary toxicity in the hamster by the antioxidant amifostine

Autor: Charles Kuhn, B S Anabela Santos-Moore, Paul Calabresi, Linda Nici

Publikováno v: Cancer. 83:2008-2014

BACKGROUND Bleomycin produces lung fibrosis in a wide variety of species. In humans, it can cause significant morbidity and mortality when used to treat malignancies such as lymphoma and testicular carcinoma. In rodents, it has been extensively used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeb4b9d05836e668d4e6f817f48616e
https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<2008::aid-cncr18>3.0.co

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1α,25-dihydroxy-24-oxo-16-ene vitamin D3, a metabolite of a synthetic vitamin D3 analog, 1α,25-dihydroxy-16-ene vitamin D3, is equipotent to its parent in modulating growth and differentiation of human leukemic cells

Autor: Anabela Santos-Moore, Mei-Ling Siu-Caldera, G. Satyanarayana Reddy, Yan Yun Liu, Sara Peleg, Milan R. Uskokovic, Surendra Sharma, Jeffrey Clark

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 59:405-412

1alpha,25(OH)2-16-ene-D3, a synthetic analog of the steroid hormone, 1alpha,25(OH)2D3, has great potential to become a drug in the treatment of leukemia and other proliferative disorders, because of its minimal in vivo calcemic activity associated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d057047e4025d45820e9470ca7fbcba9
https://doi.org/10.1016/s0960-0760(96)00134-3

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Characterization of a vitamin D3-resistant human chronic myelogenous leukemia cell line

Autor: Abbey L. Maizel, Jeffrey Clark, Marshall R. Posner, Varman Samuel, Stephen R. Lasky, Keigo Iwata, Anabel Santos-Moore, Andrew Yen

Publikováno v: Blood. 84:4283-4294

A variant of the chronic myelogenous leukemia cell line, RWLeu-4, that is resistant to the antiproliferative effects of vitamin D3 was established. Although RWLeu-4 proliferation is inhibited by 1 nmol/L vitamin D3, the resistant cells (JMRD3) contin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::208ed05cf7cbb6f60af1d2eef3dfac38
https://doi.org/10.1182/blood.v84.12.4283.bloodjournal84124283

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Metabolism and biological activity of 1,25(OH)2D2 and its metabolites in a chronic myelogenous leukemia cell line, rwleu-4

Autor: S. Lasky, C. Eil, G.P. Reddy, G.S. Reddy, K.F. Wankadiya, Jeffrey Clark, K-Y. Tserng, Ronald L. Horst, A. Santos-Moore, Milan R. Uskokovic

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 3:1873-1878

We previously described the metabolism of 1,25(OH)2D2 into various side chain hydroxylated metabolites formed as a result of C-24, C-26 and C-28 hydroxylations in rat kidney24. We now demonstrate c-24 hydroxylation of 1,25(OH)2D2 in human leukemic ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e0bf28c02dd0ec6cb998a9827d93463
https://doi.org/10.1016/s0960-894x(00)80123-7

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Human rights clauses : unraveling the pattern of implementation

Autor: SANTOS MOORE, Carla

Defence date: 20 October 2006 Supervisor: T. Risse PDF of thesis uploaded from the Library digitised archive of EUI PhD theses completed between 2013 and 2017

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______151::1bbe2143c0dfba20f089c06faead3c13
https://hdl.handle.net/1814/6351

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Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the ras signaling pathway

Autor: J W, Clark, A, Santos-Moore, L E, Stevenson, A R, Frackelton

Publikováno v: International journal of cancer. 65(2)

Breast cancers frequently over-express a number of growth factor receptors. In addition, elevated src family kinase activity is present in a percentage of these neoplasms and has been implicated in signal transduction in these cells. Therefore, inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d320847562fc4517532b414423523146
https://pubmed.ncbi.nlm.nih.gov/8567115

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