A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosis.

Autor: Santos-Júnior PFDS; Pharmaceutical Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, Sergipe 49100-001, Brazil., Batista VM; Research Group of Biological and Molecular Chemistry, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões campus, 57072-970 Alagoas, Maceió, Brazil., Nascimento IJDS; Post-Graduation Program of Pharmaceutical Sciences, Pharmacy Department, State University of Paraíba, Campina Grande, Brazil., Nunes IC; Research Group of Biological and Molecular Chemistry, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões campus, 57072-970 Alagoas, Maceió, Brazil., Silva LR; Research Group of Biological and Molecular Chemistry, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões campus, 57072-970 Alagoas, Maceió, Brazil., Costa CACB; Department of Chemistry, Federal Institute of Alagoas, Maceió campus, Mizael Domingues Street, 57020-600 Maceió, Alagoas, Brazil., Freitas JD; Department of Chemistry, Federal Institute of Alagoas, Maceió campus, Mizael Domingues Street, 57020-600 Maceió, Alagoas, Brazil., Quintans-Júnior LJ; Pharmaceutical Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, Sergipe 49100-001, Brazil., Araújo-Júnior JX; Laboratory of Medicinal Chemistry, Institute of Pharmaceutical Sciences, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões campus, 57072-970 Alagoas, Maceió, Brazil., Freitas MEG; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China., Green KD; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, 40536-0596, United States., Garneau-Tsodikova S; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, 40536-0596, United States., Mendonça-Júnior FJB; Post-Graduation Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba, João Pessoa, Brazil., Rodrigues-Junior VS; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil; Post-Graduation Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba, João Pessoa, Brazil., Silva-Júnior EFD; Research Group of Biological and Molecular Chemistry, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões campus, 57072-970 Alagoas, Maceió, Brazil. Electronic address: edeildo.junior@iqb.ufal.br.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Jun 15; Vol. 108, pp. 117774. Date of Electronic Publication: 2024 May 26.

Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.

Autor: Nascimento IJDS; Chemistry and Biotechnology Institute, Federal University of Alagoas, Maceió, Brazil., Santos-Júnior PFDS; Chemistry and Biotechnology Institute, Federal University of Alagoas, Maceió, Brazil., Aquino TM; Chemistry and Biotechnology Institute, Federal University of Alagoas, Maceió, Brazil., Araújo-Júnior JX; Laboratory of Medicinal Chemistry, Pharmaceutical Sciences Institute, Federal University of Alagoas, Maceió, Brazil., Silva-Júnior EFD; Chemistry and Biotechnology Institute, Federal University of Alagoas, Maceió, Brazil. Electronic address: edeildo.junior@iqb.ufal.br.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2021 Nov 15; Vol. 224, pp. 113698. Date of Electronic Publication: 2021 Jul 13.