Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Santos de Dios, Eugenio"'
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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© 2021 by the authors. Recent reports have identified rare, biallelic damaging variants of the AGTPBP1 gene that cause a novel and documented human disease known as childhood-onset neurodegeneration with cerebellar atrophy (CONDCA), linking loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::67ebab82c94dcdc8c1f85ac9617c4339
http://hdl.handle.net/10261/262243
http://hdl.handle.net/10261/262243
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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© 2021 by the authors. The SOS family of Ras-GEFs encompasses two highly homologous and widely expressed members, SOS1 and SOS2. Despite their similar structures and expression patterns, early studies of constitutive KO mice showing that SOS1-KO mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::b6e2f5bc0cd6903486981200e355fe7f
http://hdl.handle.net/10261/262153
http://hdl.handle.net/10261/262153
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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© 2020 The Author(s). SOS1 and SOS2 are the most universal and widely expressed family of guanine exchange factors (GEFs) capable or activating RAS or RAC1 proteins in metazoan cells. SOS proteins contain a sequence of modular domains that are respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::02838de700bc6657927a8d5b41462d45
http://hdl.handle.net/10261/226555
http://hdl.handle.net/10261/226555
Autor:
Santos de Dios, Eugenio, Crespo, Piero
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Data accumulated over more than three decades demonstrate that the assembly of macrocomplexes, mainly of dimers, is widespread among the members of the different tiers that constitute the RAS-ERK pathway. In this issue of Science Signaling, Yuan et a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::a2e56f27588b4ef029b6057dfccd74f6
http://hdl.handle.net/10261/245403
http://hdl.handle.net/10261/245403
Autor:
Fuentes Mateos, Rocío, Jimeno, David, Gómez, Carmela, Santos de Dios, Eugenio, Fernández-Medarde, Alberto
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Resumen del póster presentado al XXXIX Congreso de la Sociedad Española de Bioquímica y Biología Molecular, celebrado en Salamanca del 5 al 8 de septiembre de 2016.
The canonical members of the Ras gene family (H-ras, N-ras, and K-ras) encod
The canonical members of the Ras gene family (H-ras, N-ras, and K-ras) encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cb8429607c85b2ed1a2d73e465f21355
http://hdl.handle.net/10261/169481
http://hdl.handle.net/10261/169481
Autor:
Jimeno, David, Gómez, Carmela, Calzada, Nuria, Villa, Pedro de la, Lillo, Concepción, Santos de Dios, Eugenio
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Resumen del póster presentado al XXXIX Congreso de la Sociedad Española de Bioquímica y Biología Molecular, celebrado en Salamanca del 5 al 8 de septiembre de 2016.
Analyses of RasGRF1 knockout (GRF1-KO), GRF2-KO and the GRF1/2 double-KO mou
Analyses of RasGRF1 knockout (GRF1-KO), GRF2-KO and the GRF1/2 double-KO mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b3199f4a60c720ffd216eb9cfc1c4a43
http://hdl.handle.net/10261/169554
http://hdl.handle.net/10261/169554
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8229 (2009)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
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PLoS ONE; Vol 4
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
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PLoS ONE; Vol 4
[Background]: Vav1 and RasGRF2 are GDP/GTP exchange factors for Ras superfamily GTPases with roles in the development and/or effector functions of T–lymphocytes. [Methodology/Principal Findings]: Given that the phenotype of Vav1–/–, Rasgrf2–/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefb47f3bd31ebe9da6ad8d6609b5afa
http://europepmc.org/articles/PMC2788417?pdf=render
http://europepmc.org/articles/PMC2788417?pdf=render
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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[EN] The present invention lies in the field of biotechnology. It relates to a method for evaluating whether a compound is effective in the prevention and/or treatment of a disease asssociated with T-cell lymphomas.
[ES] La presente invención s
[ES] La presente invención s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cdc61bb354697810ed8e91a24c790260
http://hdl.handle.net/10261/28553
http://hdl.handle.net/10261/28553
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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[EN] The present invention lies in the field of biotechnology. It relates to a method for evaluating whether a compound is effective in the prevention and/or treatment of a disease asssociated with T-cell lymphomas. [ES] La presente invención se enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::6d83be9c135de3e45dfb1a7c2e2a4f03
http://hdl.handle.net/10261/26437
http://hdl.handle.net/10261/26437
Autor:
Esteban, Luis Miguel, Fernández-Medarde, Alberto, López, Eva, Tessarollo, Lino, Santos de Dios, Eugenio, Guerrero Arroyo, María del Carmen
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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The mammalian sos1 and sos2 genes encode highly homologous members of the Son-of-sevenless family of guanine nucleotide exchange factors. They are ubiquitously expressed and play key roles in transmission of signals initiated by surface protein tyros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::acb7aa406906c7cbf224ed5a3329300a
http://hdl.handle.net/10261/5144
http://hdl.handle.net/10261/5144