Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome.

Autor: Leiding JW; Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore; Johns Hopkins All Children's Institute for Clinical and Translational Research, Johns Hopkins All Children's Hospital, St Petersburg. Electronic address: jleidin1@jhmi.edu., Vogel TP; Department of Pediatrics, Baylor College of Medicine and William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston., Santarlas VGJ; Lake Erie College of Osteopathic Medicine, Erie., Mhaskar R; Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa., Smith MR; Department of Pediatrics, Baylor College of Medicine and William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston., Carisey A; Department of Cell and Molecular Biology, St Jude Children's Research Hospital, Memphis., Vargas-Hernández A; Department of Pediatrics, Baylor College of Medicine and William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston., Silva-Carmona M; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston., Heeg M; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg., Rensing-Ehl A; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg., Neven B; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM UMR 1163-Institut Imagine, Paris., Hadjadj J; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM UMR 1163-Institut Imagine, Paris., Hambleton S; Newcastle University Translational and Clinical Research Institute, Newcastle (United Kingdom)., Ronan Leahy T; Children's Health Ireland at Crumlin, Dublin., Meesilpavikai K; Department of Internal Medicine, Division of Clinical Immunology and Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Cunningham-Rundles C; Department of Medicine, Mount Sinai School of Medicine, New York., Dutmer CM; Children's Hospital Colorado, University of Colorado School of Medicine, Aurora., Sharapova SO; Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk., Taskinen M; New Children's Hospital, Pediatric Research Center, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Turku and Kuopio, Finland., Chua I; Department of Rheumatology, Immunology and Allergy, Christchurch Hospital, Christchurch; Clinical Immunogenomics Research Consortium of Australasia (CIRCA)., Hague R; Royal Hospital for Children, Glasgow., Klemann C; Department of Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School, Hannover., Kostyuchenko L; Center of Pediatric Immunology, Western Ukrainian Specialized Children's Medical Centre, Lviv., Morio T; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo., Thatayatikom A; Division of Pediatric Allergy/Immunology/Rheumatology, Shands Children's Hospital, University of Florida, Gainesville., Ozen A; School of Medicine, Pediatric Allergy and Immunology, Marmara University, Istanbul., Scherbina A; Dmitry Rogachev National Medical and Research Center for Pediatric Hematology, Oncology and Immunology, Moscow., Bauer CS; Division of Allergy and Immunology, Phoenix Children's Hospital, Phoenix., Flanagan SE; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter., Gambineri E; Department of NEUROFARBA, Section of Children's Health, University of Florence, Anna Meyer Children's Hospital, Florence., Giovannini-Chami L; Pediatric Pulmonology Department, Hôpitaux pédiatriques de Nice CHU-Lenval, Nice., Heimall J; Perelman School of Medicine at University of Pennsylvania, Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia., Sullivan KE; Perelman School of Medicine at University of Pennsylvania, Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia., Allenspach E; Pediatric Immunology/Rheumatology, University of Washington, Seattle; Seattle Children's Hospital, Seattle., Romberg N; Perelman School of Medicine at University of Pennsylvania, Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia., Deane SG; Department of Allergy, The Permanente Medical Group, Sacramento, and the Division of Rheumatology/Allergy and Clinical Immunology, University of California, Davis, School of Medicine, Sacramento., Prince BT; Nationwide Children's Hospital Department of Allergy and Immunology, Columbus; College of Medicine, The Ohio State University, Columbus., Rose MJ; College of Medicine, The Ohio State University, Columbus; Division of Pediatric Hematology-Oncology, Nationwide Children's Hospital, Columbus., Bohnsack J; Department of Pediatrics, University of Utah, Salt Lake City., Mousallem T; Duke Department of Pediatric Allergy and Immunology, Durham., Jesudas R; Department of Hematology, St Jude Children's Research Hospital, Memphis., Santos Vilela MMD; Pediatric Allergy and Immunology/Center of Investigation in Pediatrics, Faculty of Medical Sciences, State University of Campinas-Unicamp, São Paulo., O'Sullivan M; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Immunology Department, Perth Children's Hospital, Nedlands., Pachlopnik Schmid J; Division of Immunology, University Children's Hospital Zurich, Children's Research Center (CRC), Zurich., Průhová Š; Department of Pediatrics, Charles University in Prague, Second Faculty of Medicine and University Hospital Motol, Prague., Klocperk A; Department of Immunology, Second Faculty of Medicine and University Hospital Motol, Charles University in Prague, Prague., Rees M; Department of Hematology, St Jude Children's Research Hospital, Memphis., Su H; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda., Bahna S; Allergy and Immunology Section, Louisiana State University Health Sciences Center, Shreveport., Baris S; School of Medicine, Pediatric Allergy and Immunology, Marmara University, Istanbul., Bartnikas LM; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston., Chang Berger A; Division of Hospital Medicine, Department of Medicine, University of California, San Francisco., Briggs TA; Division of Evolution and Genomic Sciences, School of Biological Sciences, University of Manchester, Manchester; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester., Brothers S; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Starship Children's Hospital, Auckland., Bundy V; Allergy and Immunology, University of California, Los Angeles., Chan AY; Department of Medicine, University of California, San Francisco., Chandrakasan S; Division of Bone Marrow Transplant, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta., Christiansen M; Department of Clinical Immunology, AUH, Aarhus., Cole T; Department of Allergy and Immunology, The Royal Children's Hospital, Melbourne., Cook MC; Department of Immunology and Infectious Diseases, John Curtin School of Medical Research, Australian National University, Canberra., Desai MM; Bai Jerbai Wadia Children Hospital, Mumbai, Parel., Fischer U; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich-Heine-University, Düsseldorf., Fulcher DA; Department of Immunology and Infectious Diseases, John Curtin School of Medical Research, Australian National University, Canberra., Gallo S; Department of Pediatrics, Immunology and Rheumatology Section, Puerto Montt Hospital, Puerto Montt., Gauthier A; Department of Allergy and Immunology, CHU de Québec-CHUL, Laval University Hospital Center, Laval University, Quebec City., Gennery AR; Newcastle University Translational and Clinical Research Institute, Newcastle (United Kingdom)., Gonçalo Marques J; Infectious Diseases and Immunodeficiencies Unit, Department of Pediatrics, Hospital de Santa Maria-CHULN and Faculdade de Medicina, Universidade de Lisboa, Lisbon., Gottrand F; University Lille, Inserm, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille., Grimbacher B; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg., Grunebaum E; Division of Immunology and Allergy, and the Department of Pediatrics, Developmental and Stem Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto., Haapaniemi E; Centre for Molecular Medicine Norway, Oslo; Department of Pediatric Research, Oslo., Hämäläinen S; Department of Medicine, Kuopio University Hospital, Kuopio., Heiskanen K; New Children's Hospital, Pediatric Research Center, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Turku and Kuopio, Finland., Heiskanen-Kosma T; Department of Pediatrics, Rare Diseases Unit, Kuopio University Hospital, Kuopio., Hoffman HM; Department of Pediatrics, University of California San Diego, La Jolla; Rady Children's Hospital San Diego, Division of Pediatric Allergy, Immunology, and Rheumatology, San Diego., Gonzalez-Granado LI; Pediatrics Department, University Hospital 12 de Octubre, Research Institute Hospital, School of Medicine Complutense University, Madrid., Guerrerio AL; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore., Kainulainen L; Department of Pediatrics and Medicine, Turku University Hospital, University of Turku, Turku, Finland., Kumar A; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati., Lawrence MG; University of Virginia Health, Charlottesville., Levin C; Pediatric Hematology Unit, Emek Medical Centre, Afula, and the Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa., Martelius T; Adult Immunodeficiency Unit, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki., Neth O; Pediatric Infectious Diseases, Rheumatology and Immunology Unit, Hospital Universitario Virgen del Rocio, Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain., Olbrich P; Pediatric Infectious Diseases, Rheumatology and Immunology Unit, Hospital Universitario Virgen del Rocio, Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain., Palma A; Servicio de Immunología y Reumatología, Hospital Nacional de Pediatría Prof Dr Juan P. Garrahan, Buenos Aires., Patel NC; Division of Allergy and Immunology, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta., Pozos T; Department of Clinical Immunology, Children's Minnesota, Minneapolis., Preece K; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Department of Paediatric Immunology, John Hunter Children's Hospital, Newcastle (Australia)., Lugo Reyes SO; Immunodeficiencies Research Unit, National Institute of Pediatrics, Coyoacan, Mexico City., Russell MA; University of Exeter Medical School, Exeter., Schejter Y; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Ein-Kerem Medical Center and Faculty of Medicine, Hebrew University, Jerusalem., Seroogy C; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison., Sinclair J; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Starship Children's Hospital, Auckland., Skevofilax E; Department of Pediatric Hematology-Oncology (TAO) and First Department of Pediatrics, Aghia Sophia Children's Hospital, Athens., Suan D; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Garvan Institute of Medical Research, Darlinghurst; Westmead Clinical School, University of Sydney, Westmead., Suez D; Allergy, Asthma & Immunology Clinic, PA, Irving., Szabolcs P; University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh., Velasco H; Division of Allergy and Clinical Immunology, Moinhos de Vento Hospital, Porto Alegre., Warnatz K; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg., Walkovich K; Department of Pediatrics, C. S. Mott Children's Hospital, Michigan Medicine, Ann Arbor., Worth A; Great Ormond Street Hospital for Children, London., Seppänen MRJ; Rare Disease Center, Children's Hospital, and Adult Primary Immunodeficiency Outpatient Clinic, Inflammation Center, University of Helsinki and Helsinki University Hospital, Helsinki., Torgerson TR; Allen Institute, Seattle., Sogkas G; Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hanover., Ehl S; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg., Tangye SG; Clinical Immunogenomics Research Consortium of Australasia (CIRCA); Garvan Institute of Medical Research, Darlinghurst; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney., Cooper MA; Department of Pediatrics, Division of Rheumatology and Immunology, Washington University School of Medicine, St Louis., Milner JD; Department of Pediatrics, Division of Allergy and Immunology, Columbia University, New York Presbyterian Hospital, New York., Forbes Satter LR; Department of Pediatrics, Baylor College of Medicine and William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston. Electronic address: lisa.forbes@bcm.edu.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Apr; Vol. 151 (4), pp. 1081-1095. Date of Electronic Publication: 2022 Oct 11.