A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells

Autor: Martins Rafael M, Pesquero João B, Santos Edson L, Machado Joel, Silva Luis S, Pereira Felipe V, Rodrigues Tiago, Santana Débora P, Smaili Soraya S, Bechara Alexandre, Monteforte Priscila T, Matsuo Alisson L, Serrano Fabiana A, Travassos Luiz R, Caires Antonio CF, Rodrigues Elaine G

Publikováno v: BMC Cancer, Vol 11, Iss 1, p 296 (2011)

Abstract Background Systemic therapy for cancer metastatic lesions is difficult and generally renders a poor clinical response. Structural analogs of cisplatin, the most widely used synthetic metal complexes, show toxic side-effects and tumor cell re

Externí odkaz: https://doaj.org/article/cbcf7e9e4a11463ab15ecd1325c6aeea

Layering and wetting transitions for an interface model

Autor: Salvador Miracle Solé

Publikováno v: Non-Equilibrium Statistical Physics Today
11th Gra\-nada Seminar
11th Gra\-nada Seminar, 2010, La Herradura (Granada), Spain. pp.190-194

We study the solid-on-solid interface model above a horizontal wall in three dimensional space, with an attractive interaction when the interface is in contact with the wall, at low temperatures. The system presents a sequence of layering transitions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0a776404c6839ed2b5a021ba5c7554
https://doi.org/10.1063/1.3569499

Two-Phase Multiscale FEM Modelling of Macrosegregation Formation in Steel Slabs

Autor: Michel Bellet

Publikováno v: AIP Conference Proceedings
Numiform 2007, 9th International Conference on Numerical Methods in Industrial Forming Processes
Numiform 2007, 9th International Conference on Numerical Methods in Industrial Forming Processes, Jun 2007, Porto, Portugal. p. 1369-1374, ⟨10.1063/1.2741000⟩

International audience; The conservation equations of a coupled thermomechanical - solute transport model to be applied in mushy zones are first recalled. Then the numerical implementation is discussed, in the context of steel continuous casting mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf8de6fb9217862d2a3d242ea6f4dc6
https://doi.org/10.1063/1.2741000

Cross-environmental cycling of antimicrobial resistance in agricultural areas fertilized with poultry litter: A one health approach.

Autor: Lopes EDS; Laboratório de Genética Microbiana, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil., Ferreira Santaren KC; Laboratório de Genética Microbiana, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil., Araujo de Souza LC; Laboratório de Genética Microbiana, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil., Parente CET; Laboratório de Estudos Ambientais Olaf Malm, Instituto de Biofísica Carlos Chagas Filho, UFRJ, RJ, Brazil., Picão RC; Laboratório de Investigação em Microbiologia Médica, Instituto de Microbiologia Paulo de Góes, UFRJ, RJ, Brazil., Jurelevicius DA; Laboratório de Biotecnologia e Ecologia Microbiana, Instituto de Microbiologia Paulo de Góes, UFRJ, RJ, Brazil., Seldin L; Laboratório de Genética Microbiana, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil. Electronic address: lseldin@micro.ufrj.br.

Publikováno v: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2024 Dec 15; Vol. 363 (Pt 1), pp. 125177. Date of Electronic Publication: 2024 Oct 22.

Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction.

Autor: Costa RHSD; Veterinary Medicine Course, Maurício de Nassau University Center, Juazeiro do Norte 63010-475, CE, Brazil.; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil., Pessoa RT; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil., Silva EDS; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil., Araujo IM; Laboratory of Microbiology and Molecular Biology, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Crato 63105-000, CE, Brazil., Gonçalves SA; Laboratory of Microbiology and Molecular Biology, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Crato 63105-000, CE, Brazil., Rocha JE; Laboratory of Microbiology and Molecular Biology, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Crato 63105-000, CE, Brazil., Pereira Junior FN; Center for Agricultural and Biodiversity Sciences, Federal University of Cariri, Crato 63130-025, CE, Brazil., Oliveira NC; Department of Physics, Regional University of Cariri, Juazeiro do Norte 63041-145, CE, Brazil., Oliveira VM; Program in Natural Sciences, State University of Ceará, Fortaleza 60714-903, CE, Brazil., Rocha MND; Program in Natural Sciences, State University of Ceará, Fortaleza 60714-903, CE, Brazil., Marinho ES; Program in Natural Sciences, State University of Ceará, Fortaleza 60714-903, CE, Brazil., Kelly Gomes de Carvalho N; Laboratory of Research and Natural Product (LPPN), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil., Galberto Martins da Costa J; Laboratory of Research and Natural Product (LPPN), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil., Santos HSD; Center for Exact Sciences and Technology, Vale do Acaraú University, Sobral 62040-370, CE, Brazil., Menezes IRA; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, CE, Brazil.

Publikováno v: Pharmaceutics [Pharmaceutics] 2024 Nov 18; Vol. 16 (11). Date of Electronic Publication: 2024 Nov 18.