Case Report: Coinfection of Leprosy and Chronic Mucocutaneous Candidiasis in a Family with STAT1 Gain-of-Function Mutation.

Autor: de Oliveira Rekowski LL; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Caldas GC; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Menezes-Silva L; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Santos CNO; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Magalhães LS; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Institute of Biological and Health Sciences, Federal University of Alagoas, Maceió, Brazil., Cazzaniga RA; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil., Dos Santos NA; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Santos PL; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Louzada da Silva RL; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil., da Silva AM; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Holland SM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., de Jesus AR; Laboratory of Immunology and Molecular Biology, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil.

Publikováno v: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Nov 05. Date of Electronic Publication: 2024 Nov 05.

FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design.

Autor: Ng WH; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia.; Global Virus Network (GVN) Centre of Excellence in Arboviruses, Griffith University, Gold Coast, QLD, Australia.; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia., Liu X; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia.; Global Virus Network (GVN) Centre of Excellence in Arboviruses, Griffith University, Gold Coast, QLD, Australia.; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia., Ling ZL; Viral Immunopathology Laboratory, Infection, Immunity and Inflammation Research Theme, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2006, Australia.; Sydney Institute for Infectious Diseases, Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia., Santos CNO; Division of Immunology and Molecular Biology Laboratory, University Hospital/EBSERH, Federal University of Sergipe (UFS), Aracaju, Brazil., Magalhães LS; Division of Immunology and Molecular Biology Laboratory, University Hospital/EBSERH, Federal University of Sergipe (UFS), Aracaju, Brazil., Kueh AJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, 3050, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, 3050, Australia., Taylor A; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia.; Global Virus Network (GVN) Centre of Excellence in Arboviruses, Griffith University, Gold Coast, QLD, Australia.; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia., Freitas JR; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia.; Global Virus Network (GVN) Centre of Excellence in Arboviruses, Griffith University, Gold Coast, QLD, Australia.; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia., Koit S; Institute of Technology, University of Tartu, Tartu, Estonia., Wang S; Institute of Technology, University of Tartu, Tartu, Estonia., Lloyd AR; Viral Immunology Systems Program, Kirby Institute, University of New South Wales, Kensington, NSW, Australia., Teixeira MM; Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Merits A; Institute of Technology, University of Tartu, Tartu, Estonia., Almeida RP; Division of Immunology and Molecular Biology Laboratory, University Hospital/EBSERH, Federal University of Sergipe (UFS), Aracaju, Brazil., King NJC; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia.; Viral Immunopathology Laboratory, Infection, Immunity and Inflammation Research Theme, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2006, Australia.; Sydney Institute for Infectious Diseases, Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia., Mahalingam S; Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, 4222, Australia. s.mahalingam@griffith.edu.au.; Global Virus Network (GVN) Centre of Excellence in Arboviruses, Griffith University, Gold Coast, QLD, Australia. s.mahalingam@griffith.edu.au.; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia. s.mahalingam@griffith.edu.au.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 26; Vol. 14 (1), pp. 6605. Date of Electronic Publication: 2023 Oct 26.

sTREM-1 and TNF-α levels are associated with the clinical outcome of leprosy patients.

Autor: Bezerra-Santos M; Centro de Ciências Médicas e Enfermagem, Universidade Federal de Alagoas, Maceió, Brazil.; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Bomfim LGS; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Santos CNO; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Cunha MWN; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil., de Moraes EJR; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil., Cazzaniga RA; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Tenório MDL; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.; Departamento de Dermatologia, Hospital Universitário, Universidade Federal de Sergipe, Aracaju, Brazil., Araujo JMS; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.; Departamento de Dermatologia, Hospital Universitário, Universidade Federal de Sergipe, Aracaju, Brazil., Menezes-Silva L; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil., Magalhães LS; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Barreto AS; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., Reed SG; Host Directed Therapeutics (HDT) Bio Corp, Seattle, WA, United States., Duthie MS; Host Directed Therapeutics (HDT) Bio Corp, Seattle, WA, United States., Lipscomb MW; Department of Pharmacology, University of Minnesota, Minneapolis, MN, United States., de Almeida RP; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.; Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, Brazil.; Instituto de Investigação em Imunologia (III), Institutos Nacionais de Ciência e Tecnologia (INCTs), Conselho Nacional de Pesquisa e Tecnologia (CNPq), São Paulo, Brazil., de Moura TR; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil., de Jesus AR; Laboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.; Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, Brazil.; Instituto de Investigação em Imunologia (III), Institutos Nacionais de Ciência e Tecnologia (INCTs), Conselho Nacional de Pesquisa e Tecnologia (CNPq), São Paulo, Brazil.

Publikováno v: Frontiers in medicine [Front Med (Lausanne)] 2023 Jun 29; Vol. 10, pp. 1177375. Date of Electronic Publication: 2023 Jun 29 (Print Publication: 2023).

Use of N-acetylcysteine as treatment adjuvant regulates immune response in visceral leishmaniasis: Pilot clinical trial and in vitro experiments.

Autor: Magalhães LS; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Sector of Parasitology and Pathology, Biological and Health Sciences Institute, Federal University of Alagoas, Maceió, Brazil., Melo EV; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil., Damascena NP; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil., Albuquerque ACB; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil., Santos CNO; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil., Rebouças MC; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Bezerra MO; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil., Louzada da Silva R; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Department of Health Education, Federal University of Sergipe, Lagarto, Brazil., de Oliveira FA; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Santos PL; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Health Education, Federal University of Sergipe, Lagarto, Brazil., da Silva JS; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Lipscomb MW; Department of Pharmacology, University of Minnesota, Minneapolis, MN, United States., da Silva ÂM; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil., de Jesus AR; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil.; Immunology Institute of Investigation (iii), National Institute of Science and Technology (INCT), Brazilian Research and Technology Council (CNPq), São Paulo, Brazil., de Almeida RP; Laboratory of Immunology and Molecular Biology, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital-Empresa Brasileira de Serviços Hospitalares (EBSERH), Federal University of Sergipe, Aracaju, Brazil.; Immunology Institute of Investigation (iii), National Institute of Science and Technology (INCT), Brazilian Research and Technology Council (CNPq), São Paulo, Brazil.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Nov 24; Vol. 12, pp. 1045668. Date of Electronic Publication: 2022 Nov 24 (Print Publication: 2022).

Association of IL-9, IL-10, and IL-17 Cytokines With Hepatic Fibrosis in Human Schistosoma mansoni Infection.

Autor: Franco KGS; Image and Graphic Methods Unit, University Hospital, Federal Sergipe University, Aracaju, Brazil.; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil., de Amorim FJR; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., Santos MA; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Rollemberg CVV; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., de Oliveira FA; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., França AVC; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Hepatology Service, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Santos CNO; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., Magalhães LS; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., Cazzaniga RA; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil., de Lima FS; Hepatology Service, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Benevides L; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Carregaro V; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Silva JS; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Brito HLF; Division of Pathology, University Hospital, Federal University of Sergipe, Aracaju, Brazil., Fernandes DA; Image and Graphic Methods Unit, University Hospital, Federal Sergipe University, Aracaju, Brazil., da Silva ÂM; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Infectology Service, University Hospital, Federal University of Sergipe, Sergipe, Brazil., de Almeida RP; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Immunology Institute of Investigation (III), National Institute of Science and Technology (INCT), Brazilian Research and Technology Council (CNPq), São Paulo, Brazil., Bezerra-Santos M; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil.; Department of Morphology, Federal University of Sergipe, São Cristóvão, Brazil., de Jesus AR; Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.; Laboratory of Molecular Biology, University Hospital, Federal Sergipe University, Aracaju, Brazil.; Department of Medicine, University Hospital, Federal University of Sergipe, Aracaju, Brazil.; Immunology Institute of Investigation (III), National Institute of Science and Technology (INCT), Brazilian Research and Technology Council (CNPq), São Paulo, Brazil.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Dec 14; Vol. 12, pp. 779534. Date of Electronic Publication: 2021 Dec 14 (Print Publication: 2021).