Transcriptome analysis reveals tumor microenvironment changes in glioblastoma

Autor: Youri Hoogstrate, Kaspar Draaisma, Santoesha A. Ghisai, Levi van Hijfte, Nastaran Barin, Iris de Heer, Wouter Coppieters, Thierry P.P. van den Bosch, Anne Bolleboom, Zhenyu Gao, Arnaud J.P.E. Vincent, Latifa Karim, Manon Deckers, Martin J.B. Taphoorn, Melissa Kerkhof, Astrid Weyerbrock, Marc Sanson, Ann Hoeben, Slávka Lukacova, Giuseppe Lombardi, Sieger Leenstra, Monique Hanse, Ruth E.M. Fleischeuer, Colin Watts, Nicos Angelopoulos, Thierry Gorlia, Vassilis Golfinopoulos, Vincent Bours, Martin J. van den Bent, Pierre A. Robe, Pim J. French

Publikováno v: Cancer Cell, 41(4)
Cancer Cell, 41(4), 678-692.e7. Cell Press
Hoogstrate, Y, Draaisma, K, Ghisai, S A, van Hijfte, L, Barin, N, de Heer, I, Coppieters, W, van den Bosch, T P P, Bolleboom, A, Gao, Z, Vincent, A J P E, Karim, L, Deckers, M, Taphoorn, M J B, Kerkhof, M, Weyerbrock, A, Sanson, M, Hoeben, A, Lukacova, S, Lombardi, G, Leenstra, S, Hanse, M, Fleischeuer, R E M, Watts, C, Angelopoulos, N, Gorlia, T, Golfinopoulos, V, Bours, V, van den Bent, M J, Robe, P A & French, P J 2023, ' Transcriptome analysis reveals tumor microenvironment changes in glioblastoma ', Cancer Cell, vol. 41, no. 4, pp. 678-692.e7 . https://doi.org/10.1016/j.ccell.2023.02.019

A better understanding of transcriptional evolution of IDH-wild-type glioblastoma may be crucial for treatment optimization. Here, we perform RNA sequencing (RNA-seq) (n = 322 test, n = 245 validation) on paired primary-recurrent glioblastoma resecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb4d868c4967f080400fdfa01b352cb
https://doi.org/10.1016/j.ccell.2023.02.019