Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Santiyagu M. Savarimuthu Francis"'
Autor:
Valentine Murigneux, J. Lynn Fink, Colm Keane, Oliver Weigert, Santiyagu M. Savarimuthu Francis, Frank Vari, Simone Birch, Maher K. Gandhi, Christian Steidl, Robert Kridel, Thanh Hoang, Wolfram Klapper, Li Huang, Nicholas Matigian, Li Li, Michelle N. Wykes, Laurie H. Sehn, Peter Mollee, Joshua W.D. Tobin, Sarah Haebe, Soi Cheng Law, Jay Gunawardana, Justina Lee, Vindi Jurinovic
Publikováno v:
Journal of Clinical Oncology
PURPOSE Understanding the immunobiology of the 15% to 30% of patients with follicular lymphoma (FL) who experience progression of disease within 24 months (POD24) remains a priority. Solid tumors with low levels of intratumoral immune infiltration ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9050ac90c771dd0d74aa693b2b9263db
http://europepmc.org/articles/PMC6881104
http://europepmc.org/articles/PMC6881104
Autor:
Casey M Wright, Santiyagu M Savarimuthu Francis, Maxine E Tan, Maria U Martins, Clay Winterford, Morgan R Davidson, Edwina E Duhig, Belinda E Clarke, Nicholas K Hayward, Ian A Yang, Rayleen V Bowman, Kwun M Fong
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34943 (2012)
Asbestos-related lung cancer accounts for 4-12% of lung cancers worldwide. We have previously identified ADAM28 as a putative oncogene involved in asbestos-related lung adenocarcinoma (ARLC-AC). We hypothesised that similarly gene expression profilin
Externí odkaz:
https://doaj.org/article/a142b77e627c484fad0b95b70032d5c8
Autor:
Krishna B Sriram, Jill E Larsen, Santiyagu M Savarimuthu Francis, Casey M Wright, Belinda E Clarke, Edwina E Duhig, Kevin M Brown, Nicholas K Hayward, Ian A Yang, Rayleen V Bowman, Kwun M Fong
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30398 (2012)
BACKGROUND: Primary tumor recurrence commonly occurs after surgical resection of lung squamous cell carcinoma (SCC). Little is known about the genes driving SCC recurrence. METHODS: We used array comparative genomic hybridization (aCGH) to identify g
Externí odkaz:
https://doaj.org/article/86b50eb5b8204bd892509c95a36c73b0
Autor:
Santiyagu M Savarimuthu Francis, Jill E Larsen, Sandra J Pavey, Edwina E Duhig, Belinda E Clarke, Rayleen V Bowman, Nick K Hayward, Kwun M Fong, Ian A Yang
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17442 (2011)
Chronic obstructive pulmonary disease (COPD) is a major public health problem with increasing prevalence worldwide. The primary aim of this study was to identify genes and gene ontologies associated with COPD severity. Gene expression profiling was p
Externí odkaz:
https://doaj.org/article/31ecb76500e64c55b42b386e447119d7
Publikováno v:
Respirology. 17:590-600
Adverse health effects from air pollutants remain important, despite improvement in air quality in the past few decades. The exact mechanisms of lung injury from exposure to air pollutants are not yet fully understood. Studying the genome (e.g. singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45a33ddd4d8d86a8b5f4bd5d441f69cf
https://doi.org/10.1111/j.1440-1843.2012.02164.x
https://doi.org/10.1111/j.1440-1843.2012.02164.x
Autor:
Annette Hernadez, Clare Gould, Joshua W.D. Tobin, Sara Gabreilli, Santiyagu M. Savarimuthu Francis, Simone Birch, Soi Cheng Law, William Stevenson, Anthony J. Gill, Mark P. Hertzberg, Robert Bird, Emad Uddin Abro, Sanjiv Jain, Colm Keane, Dipti Talaulikar, Sarah-Jane Halliday, Donna Cross, Maher K. Gandhi, Grace Gifford
Publikováno v:
Blood. 132:1576-1576
LAG3 is an immune checkpoint expressed on a variety of immune cells including a sub-population of 'exhausted' effector T cells and TREGs. Early-phase studies of anti-LAG3 mAb show promise in solid and haematological cancers. We have previously demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8632d5ce724be3c06c434c3115c5aa74
https://doi.org/10.1182/blood-2018-99-112830
https://doi.org/10.1182/blood-2018-99-112830
Autor:
M. E. Tan, Kwun M. Fong, Santiyagu M. Savarimuthu Francis, Rayleen V. Bowman, Ian A. Yang, Krishna B Sriram
Publikováno v:
Current Respiratory Medicine Reviews. 6:310-321
Non-small cell lung cancer [NSCLC] is a major cause of cancer related deaths in the world. In a significant proportion of NSCLC cases, the Epidermal Growth Factor Receptor [EGFR] is over-expressed prompting the development of anti-EGFR therapies. Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61059faa90a9947f89dd3fb4889700c3
https://doi.org/10.2174/157339810793563776
https://doi.org/10.2174/157339810793563776
Autor:
Peter Mollee, Maher K. Gandhi, Mohamed Shanavas, Emad Uddin Abro, Hyung Yoo, Frank Vari, Lynn Fink, Thanh Hoang, Joshua W.D. Tobin, Li Li, Jay Gunawardana, Ti Ma, Clare Gould, Santiyagu M. Savarimuthu Francis, Simone Birch, Valentine Murigneux, Colm Keane, Paul Anthony Scuffham, Nicholas Matigian
Publikováno v:
Blood. 130:728-728
Follicular Lymphoma (FL) is the most common indolent Non-Hodgkin Lymphoma. Despite generally favorable survival outcomes, 20% of FL patients experience 'Progression of Disease within 24 months' (POD24) and subsequently have poor long-term overall sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061e4a29915ca4498c0c37dd0c5cef92
https://doi.org/10.1182/blood.v130.suppl_1.728.728
https://doi.org/10.1182/blood.v130.suppl_1.728.728
Autor:
Rodney J. Hicks, Santiyagu M. Savarimuthu Francis, Mohamed Shanavas, John F. Seymour, Joshua W.D. Tobin, Maher K. Gandhi, Mark P. Hertzberg, Colm Keane, Frank Vari, Marina Mathews
Publikováno v:
Blood. 130:825-825
T-cell infiltration of the tumor microenvironment (TME) in DLBCL is a key determinant of response to chemo-immunotherapy (Keane, Lancet Haem 2015). We have previously shown that greater diversity of the T-cell receptor (TCR) repertoire within the TME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d36107e23cd4202e24dd221f2de933
https://doi.org/10.1182/blood.v130.suppl_1.825.825
https://doi.org/10.1182/blood.v130.suppl_1.825.825
Autor:
Leanne E. Morrison, Vandana Relan, Henry M. Marshall, Ian A. Yang, Santiyagu M. Savarimuthu Francis, Janet G. Shaw, Annalicia Vaughan, Kwun M. Fong, Phoebe E. O’Hare, Felicia Goh, Annette Dent, Rayleen V. Bowman, Amy Hsiao
Publikováno v:
Expert review of respiratory medicine. 7(6)
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by persistent airflow limitation. It is the third leading cause of death worldwide, and there are currently no curative strategies for this disease. Many factors co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91edca43947f9be800ae571e48d273d
https://pubmed.ncbi.nlm.nih.gov/24160750
https://pubmed.ncbi.nlm.nih.gov/24160750