Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Santina Chiechio"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12456 (2023)
Heat shock protein 60 (Hsp60) is a member of the chaperonin family of heat shock proteins (HSPs), primarily found in the mitochondrial matrix. As a molecular chaperone, Hsp60 plays an essential role in mediating protein folding and assembly, and toge
Externí odkaz:
https://doaj.org/article/5de32e2ac82e45ae949e9706c70b0d5d
Autor:
Annamaria Fidilio, Margherita Grasso, Rita Turnaturi, Giuseppe Caruso, Federica Maria Spitale, Nunzio Vicario, Rosalba Parenti, Salvatore Spoto, Nicolò Musso, Agostino Marrazzo, Santina Chiechio, Filippo Caraci, Lorella Pasquinucci, Carmela Parenti
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Neuropathic pain is one of the most disabling forms of chronic pain and it is characterized by hyperalgesia and allodynia linked to an aberrant processing of pain transmission and to neuroinflammation. Transforming growth factor-β1 (TGF-β1) is an a
Externí odkaz:
https://doaj.org/article/2a619d81aa474855b2154eabc90b5207
Autor:
Rita Turnaturi, Santina Chiechio, Lorella Pasquinucci, Salvatore Spoto, Giuliana Costanzo, Maria Dichiara, Silvia Piana, Margherita Grasso, Emanuele Amata, Agostino Marrazzo, Carmela Parenti
Publikováno v:
Molecules, Vol 27, Iss 16, p 5135 (2022)
Although opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common drugs used in persistent pain treatment; they have shown many side effects. The development of new analgesics endowed with mu opioid receptor/delta opioid receptor
Externí odkaz:
https://doaj.org/article/fa89ceaf72aa4b489cc7b67a2f3fc901
Autor:
Nunzio Vicario, Simona Denaro, Rita Turnaturi, Lucia Longhitano, Federica Maria Spitale, Salvatore Spoto, Agostino Marrazzo, Agata Zappalà, Daniele Tibullo, Giovanni Li Volti, Santina Chiechio, Lorella Pasquinucci, Rosalba Parenti, Carmela Parenti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5864 (2022)
Chronic neuropathic pain emerges from either central or peripheral lesions inducing spontaneous or amplified responses to non-noxious stimuli. Despite different pharmacological approaches to treat such a chronic disease, neuropathic pain still repres
Externí odkaz:
https://doaj.org/article/c23c60d891384fecb919d120f421c4b7
Autor:
Santina Chiechio, Magda Zammataro, Massimo Barresi, Margherita Amenta, Gabriele Ballistreri, Simona Fabroni, Paolo Rapisarda
Publikováno v:
Molecules, Vol 26, Iss 14, p 4291 (2021)
Citrus fruits are a rich source of high-value bioactive compounds and their consumption has been associated with beneficial effects on human health. Red (blood) oranges (Citrus sinensis L. Osbeck) are particularly rich in anthocyanins (95% of which a
Externí odkaz:
https://doaj.org/article/37cc30601e884e7abcab812cfe4d8d90
Autor:
Carmelo Puglia, Debora Santonocito, Angela Bonaccorso, Teresa Musumeci, Barbara Ruozi, Rosario Pignatello, Claudia Carbone, Carmela Parenti, Santina Chiechio
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 339 (2020)
Background: Capsaicin (CPS) is a highly selective agonist of the transient receptor potential vanilloid type 1 (TRPV1) with a nanomolar affinity. High doses or prolonged exposure to CPS induces TRPV1 defunctionalization and, although this effect is c
Externí odkaz:
https://doaj.org/article/d3de4d45373f40abba27c122dc8271fb
Autor:
Carmela Parenti, Giuseppina Aricò, Santina Chiechio, Giulia Di Benedetto, Rosalba Parenti, Giovanna M. Scoto
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 16758-16769 (2015)
Harpagophytum procumbens (H. procumbens), also known as Devil’s Claw, has been used to treat a wide range of pathological conditions, including pain, arthritis and inflammation. Inflammatory mediators, released at the site of injury, can sensitize
Externí odkaz:
https://doaj.org/article/95823ffa11a74848ab250301b5fd520a
Autor:
Magda Zammataro, Sara Merlo, Massimo Barresi, Carmela Parenti, Huijuan Hu, Maria A. Sortino, Santina Chiechio
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Gender and sex differences in pain recognition and drug responses have been reported in clinical trials and experimental models of pain. Among antidepressants, contradictory results have been observed in patients treated with selective serotonin reup
Externí odkaz:
https://doaj.org/article/58f767c821d449258ba3b7daa16fb630
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 11 (2017)
Current therapy of mood disorders has several limitations. Although a high number of drugs are clinically available, as of today, nearly two-thirds of individuals do not achieve full symptomatic remission after treatment with conventional antidepress
Externí odkaz:
https://doaj.org/article/9489fe0fe7ab4f9894f4af9872d2c511
Autor:
Lucia Montenegro, Lorella Pasquinucci, Agata Zappalà, Santina Chiechio, Rita Turnaturi, Carmela Parenti
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 48 (2017)
Although rosemary essential oil (EO) shows many biological activities, its topical benefits have not been clearly demonstrated. In this work, we assessed the effects on skin hydration and elasticity of rosemary EO after topical application via gel ve
Externí odkaz:
https://doaj.org/article/4a06fccf695b4133bc87e36a8b9232ea