Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Santie, Li"'
Autor:
Gaozan Tong, Yiming Chen, Xixi Chen, Junfu Fan, Kunxuan Zhu, ZiJing Hu, Santie Li, Junjie Zhu, Jianjun Feng, Zhaohang Wu, Zhenyu Hu, Bin Zhou, Litai Jin, Hui Chen, Jingling Shen, Weitao Cong, XiaoKun Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Hepatic ischemia-reperfusion injury (IRI) is a common complication occurs during hepatic resection and transplantation. However, the mechanisms underlying hepatic IRI have not been fully elucidated. Here, we aim to explore the role of fibrob
Externí odkaz:
https://doaj.org/article/f0b2e98807a84295b6b663d8e6dc7733
Autor:
Santie, Li, Bin, Zhou, Mei, Xue, Junjie, Zhu, Gaozan, Tong, Junfu, Fan, Kunxuan, Zhu, Zijing, Hu, Rui, Chen, Yonggan, Dong, Yiming, Chen, Kwang Youl, Lee, Xiaokun, Li, Litai, Jin, Weitao, Cong
Publikováno v:
Hepatology. 77:816-833
Chronic liver diseases are associated with the development of liver fibrosis. Without treatment, liver fibrosis commonly leads to cirrhosis and HCC. FGF12 is an intracrine factor belonging to the FGF superfamily, but its role in liver homeostasis is
Autor:
Santie Li, Zhongxin Zhu, Mei Xue, Xuebo Pan, Gaozan Tong, Xinchu Yi, Junfu Fan, Yuankuan Li, Wanqian Li, Yetong Dong, Enzhao Shen, Wenjie Gong, Xuejiao Wang, Ying Yu, Yoo Jae Maeng, Xiaokun Li, Kwang Youl Lee, Litai Jin, Weitao Cong
Publikováno v:
Redox Biology, Vol 40, Iss , Pp 101859- (2021)
Hepatic ischemia-reperfusion injury (IRI) is a major complication of liver surgery and transplantation. IRI leads to hepatic parenchymal cell death, resulting in liver failure, and lacks effective therapeutic approaches. Fibroblast growth factor 10 (
Externí odkaz:
https://doaj.org/article/15aa55f4b14c46dfa089cf3d39c2f941
Autor:
Santie Li, Myeong-Ji Kim, Sung-Ho Lee, Litai Jin, Weitao Cong, Hye-Gwang Jeong, Kwang-Youl Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4312 (2021)
Metallothioneins (MTs) are intracellular cysteine-rich proteins, and their expressions are enhanced under stress conditions. MTs are recognized as having the ability to regulate redox balance in living organisms; however, their role in regulating ost
Externí odkaz:
https://doaj.org/article/31bd3ff7560e4807b88c0fb6270422ab
Autor:
Weitao Cong, Gaozan Tong, Yiming Chen, Xixi Chen, junfu fan, Kunxuan Zhu, Zijing hu, Santie Li, junjie zhu, jianjun feng, zhaohang wu, zhenyu hu, bin zhou, litai jin, jingling shen, Xiaokun Li
Hepatic ischemia-reperfusion injury (IRI) is a common complication that occurs during hepatic resection and liver transplantation. However, the mechanisms underlying hepatic IRI have not been fully elucidated. Here, we aimed to explore the role of fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea69e89640eaa92c6b56c3d90be94d23
https://doi.org/10.21203/rs.3.rs-2339357/v1
https://doi.org/10.21203/rs.3.rs-2339357/v1
Autor:
Junfu Fan, Gaozan Tong, Xixi Chen, Santie Li, Ying Yu, Shunan Zhu, Kunxuan Zhu, Zijing Hu, Yonggan Dong, Rui Chen, Junjie Zhu, Wenjie Gong, Zhicheng Hu, Bin Zhou, Yiming Chen, Litai Jin, Weitao Cong
Publikováno v:
British journal of pharmacologyREFERENCES.
Liver fibrosis is a serious cause of morbidity and mortality worldwide characterized by accumulation of extracellular matrix produced by hepatic stellate cells (HSCs). The protein kinase CK2 is a pro-survival kinase overexpressed in human tumours. Ho
Publikováno v:
Journal of Cellular and Molecular Medicine
Myocardial infarction (MI) commonly leads to cardiomyocyte apoptosis and heart failure. Mangiferin is a natural glucosylxanthone extracted from mango fruits and leaves, which has anti‐apoptotic and anti‐inflammatory properties in experimental car
Autor:
Gaozan Tong, Xixi Chen, Jongsuk Lee, Junfu Fan, Santie Li, Kunxuan Zhu, Zijing Hu, Lin Mei, Yanru Sui, Yonggan Dong, Rui Chen, Zhouxiang Jin, Bin Zhou, Xiaokun Li, Xu Wang, Weitao Cong, Peijun Huang, Litai Jin
Publikováno v:
Pharmacological research. 178
Liver fibrosis, which is characterized by excessive accumulation of extracellular matrix (ECM) primarily produced by hepatic stellate cells (HSCs), can eventually lead to cirrhosis. Fibroblast growth factor 18 (FGF18) mediates various biological acti
Autor:
Litai Jin, Yingjie Shen, Santie Li, Lu Cai, Gen Chen, Xu Wang, Yangzhi Liang, Young A Joo, Weitao Cong, Chao Niu, Zhiwei Chen, Xinchu Yi, Weijian Ye, Mei Xue
Publikováno v:
Antioxidants & Redox Signaling. 31:403-419
Aims: Cardiac-specific overexpression of metallothionein (MT) has been shown to be beneficial in ischemic heart disease, but the detailed mechanisms through which MT protects against myocardial infarction (MI) remain unknown. This study assessed the
Autor:
Yingjie Shen, Jiaojiao Liang, Mei Xue, Congcong Zhao, Litai Jin, Yangzhi Liang, Santie Li, Weitao Cong, Chao Niu, Zhongxin Zhu, Gen Chen, Hongping Zhang, Jiayong Zheng, Yang Wang, Xinchu Yi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1241-1252
Aims This study investigated the mechanism through which fibroblast growth factor 21 (FGF21) protects against angiotensin II (Ang II)-induced cardiac hypertrophy and dysfunction. Methods Male silent information regulator 1 (SIRT1) flox/flox and cardi