Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Santiago Rodriguez Ospina"'
Autor:
Marangelie Criado-Marrero, Danielle M. Blazier, Lauren A. Gould, Niat T. Gebru, Santiago Rodriguez Ospina, Debra S. Armendariz, April L. Darling, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tau accumulation and progressive loss of neurons are associated with Alzheimer’s disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While E
Externí odkaz:
https://doaj.org/article/64dff707852e4d75bac6a3dfb818855a
Autor:
Santiago Rodriguez Ospina, Danielle M. Blazier, Marangelie Criado-Marrero, Lauren A. Gould, Niat T. Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 851 (2022)
The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), ca
Externí odkaz:
https://doaj.org/article/2ece1a9b1c4a46c8bd5a5ee4da623119
Autor:
Daniel R. Dempsey, Derek A. Nichols, Matthew R. Battistini, Orville Pemberton, Santiago Rodriguez Ospina, Xiujun Zhang, Anne-Marie Carpenter, Brian G. O’Flynn, James W. Leahy, Ankush Kanwar, Eric M. Lewandowski, Yu Chen, David J. Merkler
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Agmatine N-acetyltransferase (AgmNAT) catalyzes the formation of N-acetylagmatine from acetyl-CoA and agmatine. Herein, we provide evidence that Drosophila melanogaster AgmNAT (CG15766) catalyzes the formation of N-acetylagmatine using an or
Externí odkaz:
https://doaj.org/article/b2083b0e3aaf4cd49387f1ef030550cb
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 79 (2018)
The hypothalamus-pituitary-adrenal (HPA) axis directly controls the stress response. Dysregulation of this neuroendocrine system is a common feature among psychiatric disorders. Steroid hormone receptors, like glucocorticoid receptor (GR), function a
Externí odkaz:
https://doaj.org/article/123beaf70fde4170a83a45b3de04c0e8
Autor:
Shannon E. Hill, David Beaulieu-Abdelahad, Andrea Lemus, Jack M. Webster, Santiago Rodriguez Ospina, April L. Darling, Mackenzie D. Martin, Shreya Patel, Liznair Bridenstine, Ronald Swonger, Steven Paul, Roy Blackburn, Laurent Calcul, Chad A. Dickey, James W. Leahy, Laura J. Blair
Publikováno v:
ACS Chemical Biology. 18:1124-1135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6129a08167a81c8a896513b79849deb0
https://doi.org/10.1021/acschembio.2c00919
https://doi.org/10.1021/acschembio.2c00919
Autor:
Thibault Viennet, Santiago Rodriguez Ospina, Yunqi Lu, Anna Cui, Haribabu Arthanari, Daniel R. Dempsey
Publikováno v:
Methods in Enzymology ISBN: 9780443185922
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67397ed3d727531ad46d4d43616f9e94
https://doi.org/10.1016/bs.mie.2022.09.007
https://doi.org/10.1016/bs.mie.2022.09.007
Autor:
Shannon E. Hill, Abigail R. Esquivel, Santiago Rodriguez Ospina, Lauren M. Rahal, Chad A. Dickey, Laura J. Blair
Publikováno v:
Protein Science. 31
Tauopathies, such as Alzheimer's disease, are characterized by the misfolding and progressive accumulation of the microtubule associated protein tau. Chaperones, tasked with maintaining protein homeostasis, can become imbalanced with age and contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9379724db868fe122a5474e69aa032f9
https://doi.org/10.1002/pro.4448
https://doi.org/10.1002/pro.4448
Autor:
Marangelie, Criado-Marrero, Danielle M, Blazier, Lauren A, Gould, Niat T, Gebru, Santiago, Rodriguez Ospina, Debra S, Armendariz, April L, Darling, David, Beaulieu-Abdelahad, Laura J, Blair
Publikováno v:
Scientific reports. 12(1)
Tau accumulation and progressive loss of neurons are associated with Alzheimer's disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While ER stress an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf5260f98c64dff8aea81ea036faea3f
https://pubmed.ncbi.nlm.nih.gov/35513476
https://pubmed.ncbi.nlm.nih.gov/35513476
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 79 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The hypothalamus-pituitary-adrenal (HPA) axis directly controls the stress response. Dysregulation of this neuroendocrine system is a common feature among psychiatric disorders. Steroid hormone receptors, like glucocorticoid receptor (GR), function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760b3e9ef2a760bc63edb5493c631897
http://www.mdpi.com/1422-0067/20/1/79
http://www.mdpi.com/1422-0067/20/1/79
Autor:
Danielle C. Coleman, Santiago Rodriguez Ospina, Jamie E. Meegan, Xiaoyuan Yang, Sarah Y. Yuan, Melanie Jannaway
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d2f3d3c1d8f59e67511a2ae273e059
https://doi.org/10.1096/fasebj.2018.32.1_supplement.706.1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.706.1